PDB: 5S78 — TKL ACVR1_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 5S78B
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL ACVR1 ACVR1_HUMAN 5S78B Q04771 208 499 509.0 LU8:501 Type1 Inactive DFGin 6.9916 13.4038 BLAminus -126.64, 164.14 74.77, 87.97 -101.18, 22.29 302.33, 177.25 -70.25, -15.52 in-out in 8.8007 Saltbr-out 4.6843 HRD-in -78.72, -53.62 78.73, -3.65 out-in-out SNCoio in-out ActLoopNT-in 2.9471 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iooi APE10-dihe-na -118.7, 165.64 APE9-dihe-na -61.72, 165.79 APE8-dihe-in -60.78, 129.07 APE8-rot-in 300.39 APE67-dihe-in -58.83, -27.2 -62.73, -40.71 APE12-dist-in 10.2054 APE11-dist-out 6.245 APE10-dist-out 9.0468 APE9-dist-in 3.86 Q207D None None XRAY 1.3 0.16 0.177 B 301.0 292.0 0 32 32 0 [[207, 497]] 1.0 5s78 TKL_ACVR1_HUMAN TKL 1.9e-85 292.5 2.0 267.0 266.0 353 354 355 357 359 235 248 252 333 335 334 336.0 403 385 380 379 378 377 376 375 374 284 Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 5S78A Q04771 202 499 509.0 LU8:501,LU8:506,LU8:507,XGV:508,XGV:509,XGV:510 Type1,Allosteric,Allosteric,Allosteric,Allosteric,Type1 Inactive DFGin 8.3242 13.3553 BLAminus -121.42, 162.3 75.56, 91.97 -103.54, 25.72 302.81, 1.93 -71.55, -16.97 in-out in 9.2716 Saltbr-out 6.2967 HRD-in -75.89, -55.37 78.61, -0.74 out-in-out SNCoio in-out ActLoopNT-in 2.905 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iooi APE10-dihe-na -123.0, 170.53 APE9-dihe-na -61.1, 164.91 APE8-dihe-in -65.24, 123.82 APE8-rot-in 300.79 APE67-dihe-in -58.43, -30.55 -62.87, -37.3 APE12-dist-in 9.447 APE11-dist-out 6.1418 APE10-dist-out 8.9017 APE9-dist-in 3.6758 Q207D None None XRAY 1.3 0.16 0.177 A 301.0 285.0 13 32 21 11 [[207, 497]] 1.0 5s78 TKL_ACVR1_HUMAN TKL 1.9e-85 292.5 2.0 267.0 266.0 353 354 355 357 359 235 248 252 333 335 334 336.0 403 385 380 379 378 377 376 375 374 284 Activin receptor type-1

PDB: 5S78 — TKL ACVR1_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 5S78B
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL ACVR1 ACVR1_HUMAN 5S78B Q04771 208 499 509.0 LU8:501 Type1 Inactive DFGin 6.9916 13.4038 BLAminus -126.64, 164.14 74.77, 87.97 -101.18, 22.29 302.33, 177.25 -70.25, -15.52 in-out in 8.8007 Saltbr-out 4.6843 HRD-in -78.72, -53.62 78.73, -3.65 out-in-out SNCoio in-out ActLoopNT-in 2.9471 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iooi APE10-dihe-na -118.7, 165.64 APE9-dihe-na -61.72, 165.79 APE8-dihe-in -60.78, 129.07 APE8-rot-in 300.39 APE67-dihe-in -58.83, -27.2 -62.73, -40.71 APE12-dist-in 10.2054 APE11-dist-out 6.245 APE10-dist-out 9.0468 APE9-dist-in 3.86 Q207D None None XRAY 1.3 0.16 0.177 B 301.0 292.0 0 32 32 0 [[207, 497]] 1.0 5s78 Homo sapiens TKL_ACVR1_HUMAN TKL 1.9e-85 292.5 2.0 267.0 266.0 353 354 355 357 359 235 248 252 333 335 334 336.0 403 385 380 379 378 377 376 375 374 284 Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 5S78A Q04771 202 499 509.0 LU8:501,LU8:506,LU8:507,XGV:508,XGV:509,XGV:510 Type1,Allosteric,Allosteric,Allosteric,Allosteric,Type1 Inactive DFGin 8.3242 13.3553 BLAminus -121.42, 162.3 75.56, 91.97 -103.54, 25.72 302.81, 1.93 -71.55, -16.97 in-out in 9.2716 Saltbr-out 6.2967 HRD-in -75.89, -55.37 78.61, -0.74 out-in-out SNCoio in-out ActLoopNT-in 2.905 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iooi APE10-dihe-na -123.0, 170.53 APE9-dihe-na -61.1, 164.91 APE8-dihe-in -65.24, 123.82 APE8-rot-in 300.79 APE67-dihe-in -58.43, -30.55 -62.87, -37.3 APE12-dist-in 9.447 APE11-dist-out 6.1418 APE10-dist-out 8.9017 APE9-dist-in 3.6758 Q207D None None XRAY 1.3 0.16 0.177 A 301.0 285.0 13 32 21 11 [[207, 497]] 1.0 5s78 Homo sapiens TKL_ACVR1_HUMAN TKL 1.9e-85 292.5 2.0 267.0 266.0 353 354 355 357 359 235 248 252 333 335 334 336.0 403 385 380 379 378 377 376 375 374 284 Activin receptor type-1

PDB: 5S78 — TKL ACVR1_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name