PDB: 5S77 — TKL ACVR1_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 5S77B
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL ACVR1 ACVR1_HUMAN 5S77B Q04771 205 499 509.0 LU8:501 Type1 Inactive DFGin 7.0308 13.4527 BLAminus -124.57, 162.89 76.44, 87.16 -99.57, 19.41 300.08, 174.78 -68.76, -14.31 in-out in 8.8527 Saltbr-out 4.6527 HRD-in -77.29, -55.2 78.52, -0.63 out-in-out SNCoio in-out ActLoopNT-in 2.946 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iooi APE10-dihe-na -121.24, 166.6 APE9-dihe-na -61.81, 164.74 APE8-dihe-in -60.61, 127.64 APE8-rot-in 298.26 APE67-dihe-in -59.97, -28.12 -61.67, -40.13 APE12-dist-in 10.3703 APE11-dist-out 6.2089 APE10-dist-out 8.9958 APE9-dist-in 3.8238 Q207D None None XRAY 1.31 0.166 0.185 B 301.0 292.0 3 32 32 0 [[207, 497]] 1.0 5s77 TKL_ACVR1_HUMAN TKL 1.9e-85 292.5 2.0 267.0 266.0 353 354 355 357 359 235 248 252 333 335 334 336.0 403 385 380 379 378 377 376 375 374 284 Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 5S77A Q04771 202 499 509.0 LU8:501,LU8:508,LU8:509,BAQ:510 Type1,Allosteric,Allosteric,Allosteric Inactive DFGin 8.3912 13.2913 BLAminus -123.97, 162.56 76.16, 90.86 -104.32, 25.92 302.2, 176.49 -70.33, -17.0 in-out in 9.1926 Saltbr-out 6.1664 HRD-in -75.36, -54.06 76.91, 1.59 out-in-out SNCoio in-out ActLoopNT-in 2.9281 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_nooi APE10-dihe-na -123.85, 171.29 APE9-dihe-na -63.22, 166.14 APE8-dihe-in -65.07, 121.84 APE8-rot-in 300.34 APE67-dihe-in -56.11, -31.98 -61.83, -38.01 APE12-dist-none 999.0 APE11-dist-out 6.3001 APE10-dist-out 8.8524 APE9-dist-in 3.638 Q207D None None XRAY 1.31 0.166 0.185 A 301.0 283.0 15 32 19 13 [[207, 497]] 1.0 5s77 TKL_ACVR1_HUMAN TKL 1.9e-85 292.5 2.0 267.0 266.0 353 354 355 357 359 235 248 252 333 335 334 336.0 403 385 380 379 378 377 376 375 374 284 Activin receptor type-1

PDB: 5S77 — TKL ACVR1_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 5S77B
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL ACVR1 ACVR1_HUMAN 5S77B Q04771 205 499 509.0 LU8:501 Type1 Inactive DFGin 7.0308 13.4527 BLAminus -124.57, 162.89 76.44, 87.16 -99.57, 19.41 300.08, 174.78 -68.76, -14.31 in-out in 8.8527 Saltbr-out 4.6527 HRD-in -77.29, -55.2 78.52, -0.63 out-in-out SNCoio in-out ActLoopNT-in 2.946 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iooi APE10-dihe-na -121.24, 166.6 APE9-dihe-na -61.81, 164.74 APE8-dihe-in -60.61, 127.64 APE8-rot-in 298.26 APE67-dihe-in -59.97, -28.12 -61.67, -40.13 APE12-dist-in 10.3703 APE11-dist-out 6.2089 APE10-dist-out 8.9958 APE9-dist-in 3.8238 Q207D None None XRAY 1.31 0.166 0.185 B 301.0 292.0 3 32 32 0 [[207, 497]] 1.0 5s77 Homo sapiens TKL_ACVR1_HUMAN TKL 1.9e-85 292.5 2.0 267.0 266.0 353 354 355 357 359 235 248 252 333 335 334 336.0 403 385 380 379 378 377 376 375 374 284 Activin receptor type-1
TKL ACVR1 ACVR1_HUMAN 5S77A Q04771 202 499 509.0 LU8:501,LU8:508,LU8:509,BAQ:510 Type1,Allosteric,Allosteric,Allosteric Inactive DFGin 8.3912 13.2913 BLAminus -123.97, 162.56 76.16, 90.86 -104.32, 25.92 302.2, 176.49 -70.33, -17.0 in-out in 9.1926 Saltbr-out 6.1664 HRD-in -75.36, -54.06 76.91, 1.59 out-in-out SNCoio in-out ActLoopNT-in 2.9281 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_nooi APE10-dihe-na -123.85, 171.29 APE9-dihe-na -63.22, 166.14 APE8-dihe-in -65.07, 121.84 APE8-rot-in 300.34 APE67-dihe-in -56.11, -31.98 -61.83, -38.01 APE12-dist-none 999.0 APE11-dist-out 6.3001 APE10-dist-out 8.8524 APE9-dist-in 3.638 Q207D None None XRAY 1.31 0.166 0.185 A 301.0 283.0 15 32 19 13 [[207, 497]] 1.0 5s77 Homo sapiens TKL_ACVR1_HUMAN TKL 1.9e-85 292.5 2.0 267.0 266.0 353 354 355 357 359 235 248 252 333 335 334 336.0 403 385 380 379 378 377 376 375 374 284 Activin receptor type-1

PDB: 5S77 — TKL ACVR1_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name