| Group | Gene | SwissprotID | PDB | UniprotID | First_obs_res | Last_obs_res | Length_Unp | Ligand | Ligand_type | Activity_label | Spatial_label | Phe_Glu4_dis | Phe_Lys_dis | Dihedral_label | XDFG φ,ψ |
DFG-Asp φ,ψ |
DFG-Phe φ,ψ |
DFG-Phe χ1,χ2 |
DFG-Gly φ,ψ |
ChelixSaltbr_label | Chelix_label | Lys_Glu_dis | Saltbr_label | LysNZ_GluOE_dis | HRD_label | His φ,ψ | Arg φ,ψ | SNC_label | SNCpymol_label | ActLoop_label | ActLoopNT_label | DFG6_XHRD_dis | ActLoopCT_label | APEtype | APEdihe_label | APEdist_label | APE10_dihe_label | APE10 φ,ψ | APE9_dihe_label | APE9 φ,ψ | APE8_dihe_label | APE8 φ,ψ | APE8_rotamer_label | APE8 χ1 | APE67_label | APE6 φ,ψ | APE7 φ,ψ | APE12_dist_label | APE12_DFG4_dis | APE11_dist_label | APE11_DFG4_dis | APE10_dist_label | APE10_DFG4_dis | APE9_dist_label | APE9_Arg_dis | Chain_mut | Chain_phos | Modified_aa | Method | Resolution | Rvalue | FreeRvalue | Chain_id | ChainLen | Ordered_residues | DomainBreak | ActLoopLength | ActLoopResolvedResidues | ActLoopDisorderedResidues | Kinase_domains_Unp | N_Kinase_domains_Unp | pdb | Kincore_name | hmm | Evalue | Score | hmmbeg | hmmend | hmmlen | XDFGnum | DFGnum | PHEnum | DFG4num | DFG6num | LYSnum | GLUnum | GLU4num | XHRDnum | ARGnum | HRDnum | HRDaspnum | aFaspnum | APEnum | APE6num | APE7num | APE8num | APE9num | APE10num | APE11num | APE12num | Hinge1num | Protein_name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| CAMK | CHEK1 | CHK1_HUMAN | 5OORA | O14757 | 3 | 283 | 476.0 | STU:301 | Type1 | Inactive | DFGin | 7.1962 | 13.6031 | BLAminus | -121.08, 157.07 | 78.53, 94.76 | -101.65, 21.08 | 291.71, 78.34 | -70.5, -20.28 | in-out | in | 9.325 | Saltbr-out | 5.3808 | HRD-in | -78.63, -43.76 | 73.29, -4.94 | out-in-in | SNCoii | in-in | ActLoopNT-in | 2.9061 | ActLoopCT-in | nonTYR | APEdihe_aaiii | APEdist_iiii | APE10-dihe-na | -155.81, 173.83 | APE9-dihe-na | 115.52, -146.73 | APE8-dihe-in | -140.31, 116.76 | APE8-rot-in | 299.43 | APE67-dihe-in | -68.59, -17.99 | -48.27, -41.97 | APE12-dist-in | 9.1544 | APE11-dist-in | 11.7443 | APE10-dist-in | 6.2959 | APE9-dist-in | 3.5968 | N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S | None | None | XRAY | 1.9 | 0.167 | 0.208 | A | 297.0 | 273.0 | 8 | 30 | 30 | 0 | [[9, 265]] | 1.0 | 5oor | CAMK_CHEK1_HUMAN | CAMK | 4.8e-69 | 238.4 | 2.0 | 256.0 | 255.0 | 147 | 148 | 149 | 151 | 153 | 38 | 55 | 59 | 127 | 129 | 128 | 130.0 | 190 | 177 | 172 | 171 | 170 | 169 | 168 | 167 | 166 | 85 | Serine/threonine-protein kinase Chk1 |
| Group | Gene | SwissprotID | PDB | UniprotID | First_obs_res | Last_obs_res | Length_Unp | Ligand | Ligand_type | Activity_label | Spatial_label | Phe_Glu4_dis | Phe_Lys_dis | Dihedral_label | XDFG φ,ψ |
DFG-Asp φ,ψ |
DFG-Phe φ,ψ |
DFG-Phe χ1,χ2 |
DFG-Gly φ,ψ |
ChelixSaltbr_label | Chelix_label | Lys_Glu_dis | Saltbr_label | LysNZ_GluOE_dis | HRD_label | His φ,ψ | Arg φ,ψ | SNC_label | SNCpymol_label | ActLoop_label | ActLoopNT_label | DFG6_XHRD_dis | ActLoopCT_label | APEtype | APEdihe_label | APEdist_label | APE10_dihe_label | APE10 φ,ψ | APE9_dihe_label | APE9 φ,ψ | APE8_dihe_label | APE8 φ,ψ | APE8_rotamer_label | APE8 χ1 | APE67_label | APE6 φ,ψ | APE7 φ,ψ | APE12_dist_label | APE12_DFG4_dis | APE11_dist_label | APE11_DFG4_dis | APE10_dist_label | APE10_DFG4_dis | APE9_dist_label | APE9_Arg_dis | Chain_mut | Chain_phos | Modified_aa | Method | Resolution | Rvalue | FreeRvalue | Chain_id | ChainLen | Ordered_residues | DomainBreak | ActLoopLength | ActLoopResolvedResidues | ActLoopDisorderedResidues | Kinase_domains_Unp | N_Kinase_domains_Unp | pdb | Species | Kincore_name | hmm | Evalue | Score | hmmbeg | hmmend | hmmlen | XDFGnum | DFGnum | PHEnum | DFG4num | DFG6num | LYSnum | GLUnum | GLU4num | XHRDnum | ARGnum | HRDnum | HRDaspnum | aFaspnum | APEnum | APE6num | APE7num | APE8num | APE9num | APE10num | APE11num | APE12num | Hinge1num | Protein_name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| CAMK | CHEK1 | CHK1_HUMAN | 5OORA | O14757 | 3 | 283 | 476.0 | STU:301 | Type1 | Inactive | DFGin | 7.1962 | 13.6031 | BLAminus | -121.08, 157.07 | 78.53, 94.76 | -101.65, 21.08 | 291.71, 78.34 | -70.5, -20.28 | in-out | in | 9.325 | Saltbr-out | 5.3808 | HRD-in | -78.63, -43.76 | 73.29, -4.94 | out-in-in | SNCoii | in-in | ActLoopNT-in | 2.9061 | ActLoopCT-in | nonTYR | APEdihe_aaiii | APEdist_iiii | APE10-dihe-na | -155.81, 173.83 | APE9-dihe-na | 115.52, -146.73 | APE8-dihe-in | -140.31, 116.76 | APE8-rot-in | 299.43 | APE67-dihe-in | -68.59, -17.99 | -48.27, -41.97 | APE12-dist-in | 9.1544 | APE11-dist-in | 11.7443 | APE10-dist-in | 6.2959 | APE9-dist-in | 3.5968 | N59L,V68I,L84M,Y86L,C87A,E91S,E134H,S147A,F149Y,G150S | None | None | XRAY | 1.9 | 0.167 | 0.208 | A | 297.0 | 273.0 | 8 | 30 | 30 | 0 | [[9, 265]] | 1.0 | 5oor | Homo sapiens | CAMK_CHEK1_HUMAN | CAMK | 4.8e-69 | 238.4 | 2.0 | 256.0 | 255.0 | 147 | 148 | 149 | 151 | 153 | 38 | 55 | 59 | 127 | 129 | 128 | 130.0 | 190 | 177 | 172 | 171 | 170 | 169 | 168 | 167 | 166 | 85 | Serine/threonine-protein kinase Chk1 |
| Spatial label | Dihedral label | Number of Chains | Percent | Representative |
|---|
| Group | Gene | SwissprotID | PDB | UniprotID | First_obs_res | Last_obs_res | Length_Unp | Ligand | Ligand_type | Activity_label | Spatial_label | Phe_Glu4_dis | Phe_Lys_dis | Dihedral_label | XDFG φ,ψ |
DFG-Asp φ,ψ |
DFG-Phe φ,ψ |
DFG-Phe χ1,χ2 |
DFG-Gly φ,ψ |
ChelixSaltbr_label | Chelix_label | Lys_Glu_dis | Saltbr_label | LysNZ_GluOE_dis | HRD_label | His φ,ψ | Arg φ,ψ | SNC_label | SNCpymol_label | ActLoop_label | ActLoopNT_label | DFG6_XHRD_dis | ActLoopCT_label | APEtype | APEdihe_label | APEdist_label | APE10_dihe_label | APE10 φ,ψ | APE9_dihe_label | APE9 φ,ψ | APE8_dihe_label | APE8 φ,ψ | APE8_rotamer_label | APE8 χ1 | APE67_label | APE6 φ,ψ | APE7 φ,ψ | APE12_dist_label | APE12_DFG4_dis | APE11_dist_label | APE11_DFG4_dis | APE10_dist_label | APE10_DFG4_dis | APE9_dist_label | APE9_Arg_dis | Chain_mut | Chain_phos | Modified_aa | Method | Resolution | Rvalue | FreeRvalue | Chain_id | ChainLen | Ordered_residues | DomainBreak | ActLoopLength | ActLoopResolvedResidues | ActLoopDisorderedResidues | Kinase_domains_Unp | N_Kinase_domains_Unp | pdb | Species | Kincore_name | hmm | Evalue | Score | hmmbeg | hmmend | hmmlen | XDFGnum | DFGnum | PHEnum | DFG4num | DFG6num | LYSnum | GLUnum | GLU4num | XHRDnum | ARGnum | HRDnum | HRDaspnum | aFaspnum | APEnum | APE6num | APE7num | APE8num | APE9num | APE10num | APE11num | APE12num | Hinge1num | Protein_name |
|---|