PDB: 5LW1 — CMGC MK08_HUMAN

Total number of chains: 3
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 3 100.0% 5LW1B
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC MAPK8 MK08_HUMAN 5LW1B P45983 8 362 427.0 ADN:60401 Type1 Inactive DFGin 4.4197 14.4478 ABAminus -83.29, -51.84 -118.5, -177.73 -115.08, 20.0 298.98, 87.21 71.2, -159.63 out-out out 10.4298 Saltbr-out 3.8124 HRD-in -68.61, -60.19 64.51, 12.83 out-out-out SNCooo out-out ActLoopNT-out 6.4773 ActLoopCT-out nonTYR APEdihe_aaoii APEdist_oooo APE10-dihe-na -136.58, 144.4 APE9-dihe-na -122.04, 105.79 APE8-dihe-out -71.41, -33.58 APE8-rot-in 307.18 APE67-dihe-in -61.62, -32.85 -63.18, -22.53 APE12-dist-out 20.0348 APE11-dist-out 18.2025 APE10-dist-out 13.7638 APE9-dist-out 11.7502 None None None XRAY 3.2 0.177 0.212 B 373.0 355.0 0 27 27 0 [[26, 321]] 1.0 5lw1 CMGC_MAPK8_HUMAN CMGC 4.7e-84 288.1 1.0 301.0 301.0 168 169 170 172 174 55 73 77 148 150 149 151.0 207 195 190 189 188 187 186 185 184 109 Mitogen-activated protein kinase 8
CMGC MAPK8 MK08_HUMAN 5LW1E P45983 8 362 427.0 ADN:60401 Type1 Inactive DFGin 4.1748 14.0755 ABAminus -82.51, -53.19 -119.45, -176.34 -115.64, 20.66 300.14, 87.37 72.63, -160.31 in-out in 9.9432 Saltbr-out 4.611 HRD-in -68.12, -61.52 63.83, 14.63 out-out-out SNCooo out-out ActLoopNT-out 6.8826 ActLoopCT-out nonTYR APEdihe_aaoii APEdist_oooo APE10-dihe-na -137.31, 145.55 APE9-dihe-na -120.94, 104.94 APE8-dihe-out -71.75, -32.64 APE8-rot-in 307.04 APE67-dihe-in -62.19, -31.77 -62.28, -22.63 APE12-dist-out 20.0912 APE11-dist-out 18.3879 APE10-dist-out 14.0865 APE9-dist-out 12.0009 None None None XRAY 3.2 0.177 0.212 E 373.0 355.0 0 27 27 0 [[26, 321]] 1.0 5lw1 CMGC_MAPK8_HUMAN CMGC 4.7e-84 288.1 1.0 301.0 301.0 168 169 170 172 174 55 73 77 148 150 149 151.0 207 195 190 189 188 187 186 185 184 109 Mitogen-activated protein kinase 8
CMGC MAPK8 MK08_HUMAN 5LW1H P45983 8 362 427.0 ADN:60401 Type1 Inactive DFGin 4.1303 14.3776 ABAminus -82.43, -51.23 -118.2, -176.9 -114.7, 20.75 298.45, 87.29 72.11, -159.03 out-out out 10.2847 Saltbr-out 3.7377 HRD-in -69.31, -61.29 63.64, 13.39 out-out-out SNCooo out-out ActLoopNT-out 6.4743 ActLoopCT-out nonTYR APEdihe_aaoii APEdist_oooo APE10-dihe-na -136.56, 144.9 APE9-dihe-na -119.98, 105.48 APE8-dihe-out -71.78, -33.35 APE8-rot-in 307.69 APE67-dihe-in -61.37, -31.81 -63.06, -22.73 APE12-dist-out 20.0957 APE11-dist-out 18.3691 APE10-dist-out 13.9653 APE9-dist-out 11.9943 None None None XRAY 3.2 0.177 0.212 H 373.0 355.0 0 27 27 0 [[26, 321]] 1.0 5lw1 CMGC_MAPK8_HUMAN CMGC 4.7e-84 288.1 1.0 301.0 301.0 168 169 170 172 174 55 73 77 148 150 149 151.0 207 195 190 189 188 187 186 185 184 109 Mitogen-activated protein kinase 8

PDB: 5LW1 — CMGC MK08_HUMAN

Total number of chains: 3
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 3 100.0% 5LW1B
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC MAPK8 MK08_HUMAN 5LW1B P45983 8 362 427.0 ADN:60401 Type1 Inactive DFGin 4.4197 14.4478 ABAminus -83.29, -51.84 -118.5, -177.73 -115.08, 20.0 298.98, 87.21 71.2, -159.63 out-out out 10.4298 Saltbr-out 3.8124 HRD-in -68.61, -60.19 64.51, 12.83 out-out-out SNCooo out-out ActLoopNT-out 6.4773 ActLoopCT-out nonTYR APEdihe_aaoii APEdist_oooo APE10-dihe-na -136.58, 144.4 APE9-dihe-na -122.04, 105.79 APE8-dihe-out -71.41, -33.58 APE8-rot-in 307.18 APE67-dihe-in -61.62, -32.85 -63.18, -22.53 APE12-dist-out 20.0348 APE11-dist-out 18.2025 APE10-dist-out 13.7638 APE9-dist-out 11.7502 None None None XRAY 3.2 0.177 0.212 B 373.0 355.0 0 27 27 0 [[26, 321]] 1.0 5lw1 Homo sapiens CMGC_MAPK8_HUMAN CMGC 4.7e-84 288.1 1.0 301.0 301.0 168 169 170 172 174 55 73 77 148 150 149 151.0 207 195 190 189 188 187 186 185 184 109 Mitogen-activated protein kinase 8
CMGC MAPK8 MK08_HUMAN 5LW1E P45983 8 362 427.0 ADN:60401 Type1 Inactive DFGin 4.1748 14.0755 ABAminus -82.51, -53.19 -119.45, -176.34 -115.64, 20.66 300.14, 87.37 72.63, -160.31 in-out in 9.9432 Saltbr-out 4.611 HRD-in -68.12, -61.52 63.83, 14.63 out-out-out SNCooo out-out ActLoopNT-out 6.8826 ActLoopCT-out nonTYR APEdihe_aaoii APEdist_oooo APE10-dihe-na -137.31, 145.55 APE9-dihe-na -120.94, 104.94 APE8-dihe-out -71.75, -32.64 APE8-rot-in 307.04 APE67-dihe-in -62.19, -31.77 -62.28, -22.63 APE12-dist-out 20.0912 APE11-dist-out 18.3879 APE10-dist-out 14.0865 APE9-dist-out 12.0009 None None None XRAY 3.2 0.177 0.212 E 373.0 355.0 0 27 27 0 [[26, 321]] 1.0 5lw1 Homo sapiens CMGC_MAPK8_HUMAN CMGC 4.7e-84 288.1 1.0 301.0 301.0 168 169 170 172 174 55 73 77 148 150 149 151.0 207 195 190 189 188 187 186 185 184 109 Mitogen-activated protein kinase 8
CMGC MAPK8 MK08_HUMAN 5LW1H P45983 8 362 427.0 ADN:60401 Type1 Inactive DFGin 4.1303 14.3776 ABAminus -82.43, -51.23 -118.2, -176.9 -114.7, 20.75 298.45, 87.29 72.11, -159.03 out-out out 10.2847 Saltbr-out 3.7377 HRD-in -69.31, -61.29 63.64, 13.39 out-out-out SNCooo out-out ActLoopNT-out 6.4743 ActLoopCT-out nonTYR APEdihe_aaoii APEdist_oooo APE10-dihe-na -136.56, 144.9 APE9-dihe-na -119.98, 105.48 APE8-dihe-out -71.78, -33.35 APE8-rot-in 307.69 APE67-dihe-in -61.37, -31.81 -63.06, -22.73 APE12-dist-out 20.0957 APE11-dist-out 18.3691 APE10-dist-out 13.9653 APE9-dist-out 11.9943 None None None XRAY 3.2 0.177 0.212 H 373.0 355.0 0 27 27 0 [[26, 321]] 1.0 5lw1 Homo sapiens CMGC_MAPK8_HUMAN CMGC 4.7e-84 288.1 1.0 301.0 301.0 168 169 170 172 174 55 73 77 148 150 149 151.0 207 195 190 189 188 187 186 185 184 109 Mitogen-activated protein kinase 8

PDB: 5LW1 — CMGC MK08_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name