PDB: 5KHW — TYR JAK1_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 1 50.0% 5KHWA
DFGin BLAminus 1 50.0% 5KHWB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR JAK1-2 JAK1_HUMAN 5KHWA P23458 867 1153 1154.0 ADP:1201 ATPlike Inactive DFGin 6.2929 13.5952 ABAminus -113.62, -36.19 -113.51, 112.49 -104.48, 28.51 302.05, 98.46 -68.45, -35.55 in-in in 8.0172 Saltbr-in 2.8107 HRD-in -53.69, -54.55 74.32, 4.71 in-in-in SNCiii in-in ActLoopNT-in 2.8167 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -70.25, 151.86 APE9-dihe-in -139.19, 145.92 APE8-dihe-in -78.07, 75.73 APE8-rot-na 29.65 APE67-dihe-in -77.72, -3.4 -55.44, -31.5 APE12-dist-na 13.0141 APE11-dist-na 7.3323 APE10-dist-na 9.9045 APE9-dist-in 6.0223 None PTR1034,PTR1035 PTR1034,PTR1035 XRAY 2.47 0.188 0.231 A 316.0 278.0 9 31 31 0 [[583, 847], [875, 1151]] 2.0 5khw TYR_JAK1-2_HUMAN TYR 2.6e-87 298.4 2.0 259.0 258.0 1020 1021 1022 1024 1026 908 925 929 1000 1002 1001 1003.0 1063 1051 1046 1045 1044 1043 1042 1041 1040 957 Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 5KHWB P23458 867 1153 1154.0 ADP:1201 ATPlike Inactive DFGin 6.1878 13.7874 BLAminus -126.62, -174.05 50.66, 92.23 -105.71, 28.99 301.42, 97.18 -62.73, -33.32 in-in in 7.9908 Saltbr-in 2.817 HRD-in -54.38, -55.02 75.74, 4.0 in-in-out SNCiio in-out ActLoopNT-in 2.8112 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -83.14, 18.97 APE9-dihe-in -58.32, 113.18 APE8-dihe-in -82.04, 77.86 APE8-rot-na 28.29 APE67-dihe-in -76.85, -3.42 -56.14, -32.61 APE12-dist-na 7.879 APE11-dist-na 9.6953 APE10-dist-na 6.6047 APE9-dist-in 5.9119 None PTR1034,PTR1035 PTR1034,PTR1035 XRAY 2.47 0.188 0.231 B 316.0 278.0 9 31 31 0 [[583, 847], [875, 1151]] 2.0 5khw TYR_JAK1-2_HUMAN TYR 2.6e-87 298.4 2.0 259.0 258.0 1020 1021 1022 1024 1026 908 925 929 1000 1002 1001 1003.0 1063 1051 1046 1045 1044 1043 1042 1041 1040 957 Tyrosine-protein kinase JAK1

PDB: 5KHW — TYR JAK1_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 1 50.0% 5KHWA
DFGin BLAminus 1 50.0% 5KHWB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR JAK1-2 JAK1_HUMAN 5KHWA P23458 867 1153 1154.0 ADP:1201 ATPlike Inactive DFGin 6.2929 13.5952 ABAminus -113.62, -36.19 -113.51, 112.49 -104.48, 28.51 302.05, 98.46 -68.45, -35.55 in-in in 8.0172 Saltbr-in 2.8107 HRD-in -53.69, -54.55 74.32, 4.71 in-in-in SNCiii in-in ActLoopNT-in 2.8167 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -70.25, 151.86 APE9-dihe-in -139.19, 145.92 APE8-dihe-in -78.07, 75.73 APE8-rot-na 29.65 APE67-dihe-in -77.72, -3.4 -55.44, -31.5 APE12-dist-na 13.0141 APE11-dist-na 7.3323 APE10-dist-na 9.9045 APE9-dist-in 6.0223 None PTR1034,PTR1035 PTR1034,PTR1035 XRAY 2.47 0.188 0.231 A 316.0 278.0 9 31 31 0 [[583, 847], [875, 1151]] 2.0 5khw Homo sapiens TYR_JAK1-2_HUMAN TYR 2.6e-87 298.4 2.0 259.0 258.0 1020 1021 1022 1024 1026 908 925 929 1000 1002 1001 1003.0 1063 1051 1046 1045 1044 1043 1042 1041 1040 957 Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 5KHWB P23458 867 1153 1154.0 ADP:1201 ATPlike Inactive DFGin 6.1878 13.7874 BLAminus -126.62, -174.05 50.66, 92.23 -105.71, 28.99 301.42, 97.18 -62.73, -33.32 in-in in 7.9908 Saltbr-in 2.817 HRD-in -54.38, -55.02 75.74, 4.0 in-in-out SNCiio in-out ActLoopNT-in 2.8112 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -83.14, 18.97 APE9-dihe-in -58.32, 113.18 APE8-dihe-in -82.04, 77.86 APE8-rot-na 28.29 APE67-dihe-in -76.85, -3.42 -56.14, -32.61 APE12-dist-na 7.879 APE11-dist-na 9.6953 APE10-dist-na 6.6047 APE9-dist-in 5.9119 None PTR1034,PTR1035 PTR1034,PTR1035 XRAY 2.47 0.188 0.231 B 316.0 278.0 9 31 31 0 [[583, 847], [875, 1151]] 2.0 5khw Homo sapiens TYR_JAK1-2_HUMAN TYR 2.6e-87 298.4 2.0 259.0 258.0 1020 1021 1022 1024 1026 908 925 929 1000 1002 1001 1003.0 1063 1051 1046 1045 1044 1043 1042 1041 1040 957 Tyrosine-protein kinase JAK1

PDB: 5KHW — TYR JAK1_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name