PDB: 5J1W — CMGC CLK1_HUMAN

Total number of chains: 3
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 3 100.0% 5J1WA
All chains - renumbered by
Uniprot PDB Alignment

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Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC CLK1 CLK1_HUMAN 5J1WA P49759 148 483 484.0 6FB:60506 Type1 Active DFGin 7.172 14.326 BLAminus -121.81, 173.7 71.87, 86.58 -105.02, 20.94 296.61, 84.3 -77.49, -14.22 in-in in 8.549 Saltbr-in 2.564 HRD-in -71.53, -50.92 81.49, -14.91 in-in-in SNCiii in-in ActLoopNT-in 2.904 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -138.47, 167.51 APE9-dihe-na 77.02, 140.17 APE8-dihe-in -56.28, 137.97 APE8-rot-in 295.84 APE67-dihe-in -62.06, -22.4 -61.94, -35.28 APE12-dist-in 13.605 APE11-dist-in 11.437 APE10-dist-in 7.252 APE9-dist-in 3.042 None None None XRAY 2.42 0.191 0.228 A 339 336 0 0 0 0 [[161, 477]] 1.0 5j1w CMGC_CLK1_HUMAN CMGC 2.5e-93 318.5 1 301 301 324 325 326 328 330 191 206 210 285 287 286 288 361 349 344 343 342 341 340 339 338 242 Dual specificity protein kinase CLK1
CMGC CLK1 CLK1_HUMAN 5J1WB P49759 148 482 484.0 6FB:60503 Type1 Active DFGin 7.29 14.265 BLAminus -120.99, 173.46 72.42, 86.12 -105.34, 21.92 296.07, 87.01 -75.02, -15.34 in-in in 8.585 Saltbr-in 2.585 HRD-in -69.32, -50.91 80.3, -14.73 in-in-in SNCiii in-in ActLoopNT-in 2.897 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -139.41, 167.18 APE9-dihe-na 77.9, 139.82 APE8-dihe-in -54.28, 138.17 APE8-rot-in 296.7 APE67-dihe-in -62.44, -21.37 -62.69, -34.82 APE12-dist-in 13.648 APE11-dist-in 11.342 APE10-dist-in 7.196 APE9-dist-in 3.035 None None None XRAY 2.42 0.191 0.228 B 339 335 0 0 0 0 [[161, 477]] 1.0 5j1w CMGC_CLK1_HUMAN CMGC 2.5e-93 318.5 1 301 301 324 325 326 328 330 191 206 210 285 287 286 288 361 349 344 343 342 341 340 339 338 242 Dual specificity protein kinase CLK1
CMGC CLK1 CLK1_HUMAN 5J1WC P49759 148 483 484.0 6FB:60505,6FB:60506 Type1,Allosteric Inactive DFGin 7.143 14.286 BLAminus -122.18, 173.27 71.94, 86.76 -106.83, 22.04 296.04, 87.14 -77.19, -12.48 in-in in 8.504 Saltbr-in 2.568 HRD-in -74.28, -51.47 84.87, -18.08 in-in-out SNCiio in-out ActLoopNT-in 2.88 ActLoopCT-out nonTYR APEdihe_aaiio APEdist_oioo APE10-dihe-na -128.25, 150.31 APE9-dihe-na -78.45, -169.37 APE8-dihe-in -56.02, 117.75 APE8-rot-in 301.81 APE67-dihe-out -74.26, -11.87 -128.54, 128.96 APE12-dist-out 14.754 APE11-dist-in 12.334 APE10-dist-out 9.21 APE9-dist-out 8.676 None None None XRAY 2.42 0.191 0.228 C 339 314 22 0 0 0 [[161, 477]] 1.0 5j1w CMGC_CLK1_HUMAN CMGC 2.5e-93 318.5 1 301 301 324 325 326 328 330 191 206 210 285 287 286 288 361 349 344 343 342 341 340 339 338 242 Dual specificity protein kinase CLK1

PDB: 5J1W — CMGC CLK1_HUMAN

Total number of chains: 3
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 3 100.0% 5J1WA
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC CLK1 CLK1_HUMAN 5J1WA P49759 148 483 484.0 6FB:60506 Type1 Active DFGin 7.172 14.326 BLAminus -121.81, 173.7 71.87, 86.58 -105.02, 20.94 296.61, 84.3 -77.49, -14.22 in-in in 8.549 Saltbr-in 2.564 HRD-in -71.53, -50.92 81.49, -14.91 in-in-in SNCiii in-in ActLoopNT-in 2.904 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -138.47, 167.51 APE9-dihe-na 77.02, 140.17 APE8-dihe-in -56.28, 137.97 APE8-rot-in 295.84 APE67-dihe-in -62.06, -22.4 -61.94, -35.28 APE12-dist-in 13.605 APE11-dist-in 11.437 APE10-dist-in 7.252 APE9-dist-in 3.042 None None None XRAY 2.42 0.191 0.228 A 339 336 0 0 0 0 [[161, 477]] 1.0 5j1w Homo sapiens CMGC_CLK1_HUMAN CMGC 2.5e-93 318.5 1 301 301 324 325 326 328 330 191 206 210 285 287 286 288 361 349 344 343 342 341 340 339 338 242 Dual specificity protein kinase CLK1
CMGC CLK1 CLK1_HUMAN 5J1WB P49759 148 482 484.0 6FB:60503 Type1 Active DFGin 7.29 14.265 BLAminus -120.99, 173.46 72.42, 86.12 -105.34, 21.92 296.07, 87.01 -75.02, -15.34 in-in in 8.585 Saltbr-in 2.585 HRD-in -69.32, -50.91 80.3, -14.73 in-in-in SNCiii in-in ActLoopNT-in 2.897 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -139.41, 167.18 APE9-dihe-na 77.9, 139.82 APE8-dihe-in -54.28, 138.17 APE8-rot-in 296.7 APE67-dihe-in -62.44, -21.37 -62.69, -34.82 APE12-dist-in 13.648 APE11-dist-in 11.342 APE10-dist-in 7.196 APE9-dist-in 3.035 None None None XRAY 2.42 0.191 0.228 B 339 335 0 0 0 0 [[161, 477]] 1.0 5j1w Homo sapiens CMGC_CLK1_HUMAN CMGC 2.5e-93 318.5 1 301 301 324 325 326 328 330 191 206 210 285 287 286 288 361 349 344 343 342 341 340 339 338 242 Dual specificity protein kinase CLK1
CMGC CLK1 CLK1_HUMAN 5J1WC P49759 148 483 484.0 6FB:60505,6FB:60506 Type1,Allosteric Inactive DFGin 7.143 14.286 BLAminus -122.18, 173.27 71.94, 86.76 -106.83, 22.04 296.04, 87.14 -77.19, -12.48 in-in in 8.504 Saltbr-in 2.568 HRD-in -74.28, -51.47 84.87, -18.08 in-in-out SNCiio in-out ActLoopNT-in 2.88 ActLoopCT-out nonTYR APEdihe_aaiio APEdist_oioo APE10-dihe-na -128.25, 150.31 APE9-dihe-na -78.45, -169.37 APE8-dihe-in -56.02, 117.75 APE8-rot-in 301.81 APE67-dihe-out -74.26, -11.87 -128.54, 128.96 APE12-dist-out 14.754 APE11-dist-in 12.334 APE10-dist-out 9.21 APE9-dist-out 8.676 None None None XRAY 2.42 0.191 0.228 C 339 314 22 0 0 0 [[161, 477]] 1.0 5j1w Homo sapiens CMGC_CLK1_HUMAN CMGC 2.5e-93 318.5 1 301 301 324 325 326 328 330 191 206 210 285 287 286 288 361 349 344 343 342 341 340 339 338 242 Dual specificity protein kinase CLK1

PDB: 5J1W — CMGC CLK1_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name