PDB: 5HX8 — TYR JAK1_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 2 100.0% 5HX8A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR JAK1-2 JAK1_HUMAN 5HX8A P23458 855 1154 1154.0 66P:1201 Type1 Inactive DFGin 6.449 13.6875 ABAminus -102.8, 8.3 -149.54, 137.76 -131.57, 23.74 295.19, 87.44 -55.43, -25.96 in-in in 7.9251 Saltbr-in 2.7615 HRD-in -74.69, -48.9 64.93, 4.52 in-in-in SNCiii in-in ActLoopNT-in 2.7265 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -103.85, 104.76 APE9-dihe-in -72.26, 138.18 APE8-dihe-in -80.27, 76.7 APE8-rot-na 26.46 APE67-dihe-in -75.94, -4.44 -51.82, -37.01 APE12-dist-na 11.1195 APE11-dist-na 12.2854 APE10-dist-na 11.3929 APE9-dist-in 6.6113 None PTR1034,PTR1035 PTR1034,PTR1035 XRAY 2.2 0.199 0.24 A 302.0 293.0 7 31 31 0 [[583, 847], [875, 1151]] 2.0 5hx8 TYR_JAK1-2_HUMAN TYR 2.2e-87 298.6 2.0 259.0 258.0 1020 1021 1022 1024 1026 908 925 929 1000 1002 1001 1003.0 1063 1051 1046 1045 1044 1043 1042 1041 1040 957 Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 5HX8B P23458 865 1154 1154.0 66P:1201 Type1 Inactive DFGin 6.4205 13.6309 ABAminus -110.45, 9.62 -150.03, 136.28 -131.01, 24.66 294.53, 92.56 -57.47, -31.3 in-in in 7.7687 Saltbr-in 2.7579 HRD-in -74.49, -50.24 68.18, -1.59 in-in-out SNCiio in-out ActLoopNT-in 2.7739 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -121.57, 40.76 APE9-dihe-in -71.94, 141.78 APE8-dihe-in -79.55, 77.3 APE8-rot-na 24.89 APE67-dihe-in -77.48, 1.58 -49.69, -36.95 APE12-dist-na 10.8376 APE11-dist-na 12.6929 APE10-dist-na 10.8601 APE9-dist-in 6.5503 None PTR1034,PTR1035 PTR1034,PTR1035 XRAY 2.2 0.199 0.24 B 302.0 281.0 9 31 31 0 [[583, 847], [875, 1151]] 2.0 5hx8 TYR_JAK1-2_HUMAN TYR 2.2e-87 298.6 2.0 259.0 258.0 1020 1021 1022 1024 1026 908 925 929 1000 1002 1001 1003.0 1063 1051 1046 1045 1044 1043 1042 1041 1040 957 Tyrosine-protein kinase JAK1

PDB: 5HX8 — TYR JAK1_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 2 100.0% 5HX8A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR JAK1-2 JAK1_HUMAN 5HX8A P23458 855 1154 1154.0 66P:1201 Type1 Inactive DFGin 6.449 13.6875 ABAminus -102.8, 8.3 -149.54, 137.76 -131.57, 23.74 295.19, 87.44 -55.43, -25.96 in-in in 7.9251 Saltbr-in 2.7615 HRD-in -74.69, -48.9 64.93, 4.52 in-in-in SNCiii in-in ActLoopNT-in 2.7265 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -103.85, 104.76 APE9-dihe-in -72.26, 138.18 APE8-dihe-in -80.27, 76.7 APE8-rot-na 26.46 APE67-dihe-in -75.94, -4.44 -51.82, -37.01 APE12-dist-na 11.1195 APE11-dist-na 12.2854 APE10-dist-na 11.3929 APE9-dist-in 6.6113 None PTR1034,PTR1035 PTR1034,PTR1035 XRAY 2.2 0.199 0.24 A 302.0 293.0 7 31 31 0 [[583, 847], [875, 1151]] 2.0 5hx8 Homo sapiens TYR_JAK1-2_HUMAN TYR 2.2e-87 298.6 2.0 259.0 258.0 1020 1021 1022 1024 1026 908 925 929 1000 1002 1001 1003.0 1063 1051 1046 1045 1044 1043 1042 1041 1040 957 Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 5HX8B P23458 865 1154 1154.0 66P:1201 Type1 Inactive DFGin 6.4205 13.6309 ABAminus -110.45, 9.62 -150.03, 136.28 -131.01, 24.66 294.53, 92.56 -57.47, -31.3 in-in in 7.7687 Saltbr-in 2.7579 HRD-in -74.49, -50.24 68.18, -1.59 in-in-out SNCiio in-out ActLoopNT-in 2.7739 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -121.57, 40.76 APE9-dihe-in -71.94, 141.78 APE8-dihe-in -79.55, 77.3 APE8-rot-na 24.89 APE67-dihe-in -77.48, 1.58 -49.69, -36.95 APE12-dist-na 10.8376 APE11-dist-na 12.6929 APE10-dist-na 10.8601 APE9-dist-in 6.5503 None PTR1034,PTR1035 PTR1034,PTR1035 XRAY 2.2 0.199 0.24 B 302.0 281.0 9 31 31 0 [[583, 847], [875, 1151]] 2.0 5hx8 Homo sapiens TYR_JAK1-2_HUMAN TYR 2.2e-87 298.6 2.0 259.0 258.0 1020 1021 1022 1024 1026 908 925 929 1000 1002 1001 1003.0 1063 1051 1046 1045 1044 1043 1042 1041 1040 957 Tyrosine-protein kinase JAK1

PDB: 5HX8 — TYR JAK1_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name