PDB: 5HIE — TKL BRAF_HUMAN

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBminus 4 100.0% 5HIEB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL BRAF BRAF_HUMAN 5HIEA P15056 449 722 766.0 P06:801 Type1 Inactive DFGin 8.9292 14.4485 BLBminus -141.8, -164.77 53.26, 57.86 -65.92, 138.13 285.18, 76.08 -69.2, 130.11 out-out out 15.7254 Saltbr-out 12.5 HRD-in -60.62, -46.76 71.26, -9.44 out-out-out SNCooo out-out ActLoopNT-out 12.7376 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 143.17 APE8-dihe-in -83.81, 99.59 APE8-rot-in 302.38 APE67-dihe-in -53.53, -27.96 -85.37, -23.32 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 10.1759 None None None XRAY 3.0 0.196 0.221 A 302.0 258.0 11 30 19 11 [[457, 716]] 1.0 5hie TKL_BRAF_HUMAN TKL 5.8e-80 274.6 4.0 266.0 263.0 593 594 595 597 599 483 501 505 573 575 574 576.0 638 623 618 617 616 615 614 613 612 530 Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 5HIEB P15056 449 722 766.0 P06:801 Type1 Inactive DFGin 9.0768 14.341 BLBminus -142.86, -164.65 53.45, 58.39 -66.51, 138.76 285.5, 75.66 -69.99, 128.6 out-out out 16.4397 Saltbr-out 12.3252 HRD-in -61.23, -46.57 70.13, -7.74 out-out-out SNCooo out-out ActLoopNT-out 12.5252 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_nnoo APE10-dihe-na 999.0, 61.11 APE9-dihe-na -158.28, 177.47 APE8-dihe-in -84.39, 102.56 APE8-rot-in 300.94 APE67-dihe-in -53.91, -28.83 -85.61, -22.02 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-out 14.1354 APE9-dist-out 9.8356 None None None XRAY 3.0 0.196 0.221 B 302.0 259.0 10 30 20 10 [[457, 716]] 1.0 5hie TKL_BRAF_HUMAN TKL 5.8e-80 274.6 4.0 266.0 263.0 593 594 595 597 599 483 501 505 573 575 574 576.0 638 623 618 617 616 615 614 613 612 530 Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 5HIEC P15056 449 722 766.0 P06:801 Type1 Inactive DFGin 10.205 14.4478 BLBminus -142.24, -163.89 53.8, 57.5 -66.04, 139.53 285.14, 75.68 -75.41, 148.8 out-out out 16.3072 Saltbr-out 11.8568 HRD-in -60.99, -45.77 71.53, -8.16 out-none-out SNCono none-out ActLoopNT-none 999.0 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_nnoo APE10-dihe-na 999.0, 139.61 APE9-dihe-na 88.59, -130.66 APE8-dihe-in -113.06, 104.87 APE8-rot-in 299.6 APE67-dihe-in -52.68, -29.4 -86.36, -21.79 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-out 12.1115 APE9-dist-out 10.0179 None None None XRAY 3.0 0.196 0.221 C 302.0 253.0 16 30 14 16 [[457, 716]] 1.0 5hie TKL_BRAF_HUMAN TKL 5.8e-80 274.6 4.0 266.0 263.0 593 594 595 597 599 483 501 505 573 575 574 576.0 638 623 618 617 616 615 614 613 612 530 Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 5HIED P15056 449 722 766.0 P06:801 Type1 Inactive DFGin 10.0279 14.3202 BLBminus -141.99, -164.94 53.95, 58.44 -66.89, 145.64 284.8, 75.43 -81.74, 146.41 out-out out 15.1474 Saltbr-out 11.8271 HRD-in -60.57, -44.96 73.09, -9.93 out-none-out SNCono none-out ActLoopNT-none 999.0 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_nnoo APE10-dihe-na 999.0, -51.59 APE9-dihe-na 147.01, -158.11 APE8-dihe-in -84.1, 102.2 APE8-rot-in 299.84 APE67-dihe-in -53.01, -29.18 -85.5, -22.02 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-out 14.012 APE9-dist-out 9.7896 None None None XRAY 3.0 0.196 0.221 D 302.0 253.0 16 30 14 16 [[457, 716]] 1.0 5hie TKL_BRAF_HUMAN TKL 5.8e-80 274.6 4.0 266.0 263.0 593 594 595 597 599 483 501 505 573 575 574 576.0 638 623 618 617 616 615 614 613 612 530 Serine/threonine-protein kinase B-raf

PDB: 5HIE — TKL BRAF_HUMAN

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBminus 4 100.0% 5HIEB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL BRAF BRAF_HUMAN 5HIEA P15056 449 722 766.0 P06:801 Type1 Inactive DFGin 8.9292 14.4485 BLBminus -141.8, -164.77 53.26, 57.86 -65.92, 138.13 285.18, 76.08 -69.2, 130.11 out-out out 15.7254 Saltbr-out 12.5 HRD-in -60.62, -46.76 71.26, -9.44 out-out-out SNCooo out-out ActLoopNT-out 12.7376 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 143.17 APE8-dihe-in -83.81, 99.59 APE8-rot-in 302.38 APE67-dihe-in -53.53, -27.96 -85.37, -23.32 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 10.1759 None None None XRAY 3.0 0.196 0.221 A 302.0 258.0 11 30 19 11 [[457, 716]] 1.0 5hie Homo sapiens TKL_BRAF_HUMAN TKL 5.8e-80 274.6 4.0 266.0 263.0 593 594 595 597 599 483 501 505 573 575 574 576.0 638 623 618 617 616 615 614 613 612 530 Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 5HIEB P15056 449 722 766.0 P06:801 Type1 Inactive DFGin 9.0768 14.341 BLBminus -142.86, -164.65 53.45, 58.39 -66.51, 138.76 285.5, 75.66 -69.99, 128.6 out-out out 16.4397 Saltbr-out 12.3252 HRD-in -61.23, -46.57 70.13, -7.74 out-out-out SNCooo out-out ActLoopNT-out 12.5252 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_nnoo APE10-dihe-na 999.0, 61.11 APE9-dihe-na -158.28, 177.47 APE8-dihe-in -84.39, 102.56 APE8-rot-in 300.94 APE67-dihe-in -53.91, -28.83 -85.61, -22.02 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-out 14.1354 APE9-dist-out 9.8356 None None None XRAY 3.0 0.196 0.221 B 302.0 259.0 10 30 20 10 [[457, 716]] 1.0 5hie Homo sapiens TKL_BRAF_HUMAN TKL 5.8e-80 274.6 4.0 266.0 263.0 593 594 595 597 599 483 501 505 573 575 574 576.0 638 623 618 617 616 615 614 613 612 530 Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 5HIEC P15056 449 722 766.0 P06:801 Type1 Inactive DFGin 10.205 14.4478 BLBminus -142.24, -163.89 53.8, 57.5 -66.04, 139.53 285.14, 75.68 -75.41, 148.8 out-out out 16.3072 Saltbr-out 11.8568 HRD-in -60.99, -45.77 71.53, -8.16 out-none-out SNCono none-out ActLoopNT-none 999.0 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_nnoo APE10-dihe-na 999.0, 139.61 APE9-dihe-na 88.59, -130.66 APE8-dihe-in -113.06, 104.87 APE8-rot-in 299.6 APE67-dihe-in -52.68, -29.4 -86.36, -21.79 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-out 12.1115 APE9-dist-out 10.0179 None None None XRAY 3.0 0.196 0.221 C 302.0 253.0 16 30 14 16 [[457, 716]] 1.0 5hie Homo sapiens TKL_BRAF_HUMAN TKL 5.8e-80 274.6 4.0 266.0 263.0 593 594 595 597 599 483 501 505 573 575 574 576.0 638 623 618 617 616 615 614 613 612 530 Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 5HIED P15056 449 722 766.0 P06:801 Type1 Inactive DFGin 10.0279 14.3202 BLBminus -141.99, -164.94 53.95, 58.44 -66.89, 145.64 284.8, 75.43 -81.74, 146.41 out-out out 15.1474 Saltbr-out 11.8271 HRD-in -60.57, -44.96 73.09, -9.93 out-none-out SNCono none-out ActLoopNT-none 999.0 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_nnoo APE10-dihe-na 999.0, -51.59 APE9-dihe-na 147.01, -158.11 APE8-dihe-in -84.1, 102.2 APE8-rot-in 299.84 APE67-dihe-in -53.01, -29.18 -85.5, -22.02 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-out 14.012 APE9-dist-out 9.7896 None None None XRAY 3.0 0.196 0.221 D 302.0 253.0 16 30 14 16 [[457, 716]] 1.0 5hie Homo sapiens TKL_BRAF_HUMAN TKL 5.8e-80 274.6 4.0 266.0 263.0 593 594 595 597 599 483 501 505 573 575 574 576.0 638 623 618 617 616 615 614 613 612 530 Serine/threonine-protein kinase B-raf

PDB: 5HIE — TKL BRAF_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name