| Group | Gene | SwissprotID | PDB | UniprotID | First_obs_res | Last_obs_res | Length_Unp | Ligand | Ligand_type | Activity_label | Spatial_label | Phe_Glu4_dis | Phe_Lys_dis | Dihedral_label | XDFG φ,ψ |
DFG-Asp φ,ψ |
DFG-Phe φ,ψ |
DFG-Phe χ1,χ2 |
DFG-Gly φ,ψ |
ChelixSaltbr_label | Chelix_label | Lys_Glu_dis | Saltbr_label | LysNZ_GluOE_dis | HRD_label | His φ,ψ | Arg φ,ψ | SNC_label | SNCpymol_label | ActLoop_label | ActLoopNT_label | DFG6_XHRD_dis | ActLoopCT_label | APEtype | APEdihe_label | APEdist_label | APE10_dihe_label | APE10 φ,ψ | APE9_dihe_label | APE9 φ,ψ | APE8_dihe_label | APE8 φ,ψ | APE8_rotamer_label | APE8 χ1 | APE67_label | APE6 φ,ψ | APE7 φ,ψ | APE12_dist_label | APE12_DFG4_dis | APE11_dist_label | APE11_DFG4_dis | APE10_dist_label | APE10_DFG4_dis | APE9_dist_label | APE9_Arg_dis | Chain_mut | Chain_phos | Modified_aa | Method | Resolution | Rvalue | FreeRvalue | Chain_id | ChainLen | Ordered_residues | DomainBreak | ActLoopLength | ActLoopResolvedResidues | ActLoopDisorderedResidues | Kinase_domains_Unp | N_Kinase_domains_Unp | pdb | Kincore_name | hmm | Evalue | Score | hmmbeg | hmmend | hmmlen | XDFGnum | DFGnum | PHEnum | DFG4num | DFG6num | LYSnum | GLUnum | GLU4num | XHRDnum | ARGnum | HRDnum | HRDaspnum | aFaspnum | APEnum | APE6num | APE7num | APE8num | APE9num | APE10num | APE11num | APE12num | Hinge1num | Protein_name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| TYR | PTK6 | PTK6_HUMAN | 5H2UA | Q13882 | 185 | 446 | 451.0 | 1N1:60501 | Type1 | Inactive | DFGin | 5.9983 | 13.4628 | BLBplus | -115.66, 172.2 | 65.44, 13.7 | -58.08, 130.19 | 47.49, 85.54 | 66.94, -1.55 | out-out | out | 14.1683 | Saltbr-out | 16.091 | HRD-in | -72.57, -54.48 | 85.53, -13.44 | out-out-out | SNCooo | out-out | ActLoopNT-out | 7.2608 | ActLoopCT-out | TYR | APEdihe_oooai | APEdist_aaao | APE10-dihe-out | 72.03, 33.67 | APE9-dihe-out | -55.65, -32.62 | APE8-dihe-out | -63.18, -18.16 | APE8-rot-na | 340.69 | APE67-dihe-in | -82.41, -18.93 | -56.57, -27.65 | APE12-dist-na | 16.3439 | APE11-dist-na | 20.6081 | APE10-dist-na | 18.2629 | APE9-dist-out | 11.0621 | C433T | None | None | XRAY | 2.24 | 0.208 | 0.26 | A | 267.0 | 261.0 | 1 | 28 | 28 | 0 | [[191, 443]] | 1.0 | 5h2u | TYR_PTK6_HUMAN | TYR | 9.8e-89 | 303.0 | 2.0 | 260.0 | 259.0 | 329 | 330 | 331 | 333 | 335 | 219 | 235 | 239 | 309 | 311 | 310 | 312.0 | 369 | 357 | 352 | 351 | 350 | 349 | 348 | 347 | 346 | 265 | Protein-tyrosine kinase 6 |
| TYR | PTK6 | PTK6_HUMAN | 5H2UB | Q13882 | 185 | 446 | 451.0 | 1N1:60501 | Type1 | Inactive | DFGin | 6.0808 | 13.3427 | BLBplus | -112.62, 168.56 | 69.96, 13.64 | -58.15, 126.09 | 44.9, 88.52 | 70.74, 0.77 | out-out | out | 14.3036 | Saltbr-out | 15.9567 | HRD-in | -65.56, -52.22 | 84.8, -15.83 | out-out-out | SNCooo | out-out | ActLoopNT-out | 7.0671 | ActLoopCT-out | TYR | APEdihe_oooai | APEdist_aaao | APE10-dihe-out | 67.1, 31.04 | APE9-dihe-out | -51.48, -32.62 | APE8-dihe-out | -56.92, -21.84 | APE8-rot-na | 331.92 | APE67-dihe-in | -82.05, -11.15 | -61.67, -25.37 | APE12-dist-na | 16.2609 | APE11-dist-na | 20.2262 | APE10-dist-na | 17.9045 | APE9-dist-out | 11.0552 | C433T | None | None | XRAY | 2.24 | 0.208 | 0.26 | B | 267.0 | 261.0 | 1 | 28 | 28 | 0 | [[191, 443]] | 1.0 | 5h2u | TYR_PTK6_HUMAN | TYR | 9.8e-89 | 303.0 | 2.0 | 260.0 | 259.0 | 329 | 330 | 331 | 333 | 335 | 219 | 235 | 239 | 309 | 311 | 310 | 312.0 | 369 | 357 | 352 | 351 | 350 | 349 | 348 | 347 | 346 | 265 | Protein-tyrosine kinase 6 |
| TYR | PTK6 | PTK6_HUMAN | 5H2UC | Q13882 | 185 | 446 | 451.0 | 1N1:60501 | Type1 | Inactive | DFGin | 5.9677 | 13.6341 | BLBplus | -101.49, 165.12 | 71.33, 11.9 | -56.7, 126.68 | 46.28, 85.99 | 72.45, -1.55 | out-out | out | 14.2504 | Saltbr-out | 15.3617 | HRD-in | -69.3, -53.89 | 83.99, -9.53 | out-out-out | SNCooo | out-out | ActLoopNT-out | 7.1583 | ActLoopCT-out | TYR | APEdihe_oooai | APEdist_aaao | APE10-dihe-out | 66.45, 29.68 | APE9-dihe-out | -47.22, -37.04 | APE8-dihe-out | -58.56, -24.03 | APE8-rot-na | 334.48 | APE67-dihe-in | -84.14, -9.31 | -53.24, -25.76 | APE12-dist-na | 16.3889 | APE11-dist-na | 20.3117 | APE10-dist-na | 17.9592 | APE9-dist-out | 11.0174 | C433T | None | None | XRAY | 2.24 | 0.208 | 0.26 | C | 267.0 | 261.0 | 1 | 28 | 28 | 0 | [[191, 443]] | 1.0 | 5h2u | TYR_PTK6_HUMAN | TYR | 9.8e-89 | 303.0 | 2.0 | 260.0 | 259.0 | 329 | 330 | 331 | 333 | 335 | 219 | 235 | 239 | 309 | 311 | 310 | 312.0 | 369 | 357 | 352 | 351 | 350 | 349 | 348 | 347 | 346 | 265 | Protein-tyrosine kinase 6 |
| TYR | PTK6 | PTK6_HUMAN | 5H2UD | Q13882 | 185 | 446 | 451.0 | 1N1:60504 | Type1 | Inactive | DFGin | 6.1814 | 13.2695 | BLBplus | -112.73, 164.13 | 73.65, 11.67 | -56.94, 123.73 | 42.41, 88.79 | 73.17, 2.96 | out-out | out | 14.0107 | Saltbr-out | 15.9929 | HRD-in | -70.19, -55.11 | 88.71, -18.22 | out-out-out | SNCooo | out-out | ActLoopNT-out | 7.1947 | ActLoopCT-out | TYR | APEdihe_oooai | APEdist_aaao | APE10-dihe-out | 72.07, 30.74 | APE9-dihe-out | -48.72, -36.76 | APE8-dihe-out | -61.03, -20.74 | APE8-rot-na | 334.99 | APE67-dihe-in | -84.77, -13.01 | -55.36, -26.11 | APE12-dist-na | 16.3004 | APE11-dist-na | 20.346 | APE10-dist-na | 18.0251 | APE9-dist-out | 11.0324 | C433T | None | None | XRAY | 2.24 | 0.208 | 0.26 | D | 267.0 | 261.0 | 1 | 28 | 28 | 0 | [[191, 443]] | 1.0 | 5h2u | TYR_PTK6_HUMAN | TYR | 9.8e-89 | 303.0 | 2.0 | 260.0 | 259.0 | 329 | 330 | 331 | 333 | 335 | 219 | 235 | 239 | 309 | 311 | 310 | 312.0 | 369 | 357 | 352 | 351 | 350 | 349 | 348 | 347 | 346 | 265 | Protein-tyrosine kinase 6 |
| Group | Gene | SwissprotID | PDB | UniprotID | First_obs_res | Last_obs_res | Length_Unp | Ligand | Ligand_type | Activity_label | Spatial_label | Phe_Glu4_dis | Phe_Lys_dis | Dihedral_label | XDFG φ,ψ |
DFG-Asp φ,ψ |
DFG-Phe φ,ψ |
DFG-Phe χ1,χ2 |
DFG-Gly φ,ψ |
ChelixSaltbr_label | Chelix_label | Lys_Glu_dis | Saltbr_label | LysNZ_GluOE_dis | HRD_label | His φ,ψ | Arg φ,ψ | SNC_label | SNCpymol_label | ActLoop_label | ActLoopNT_label | DFG6_XHRD_dis | ActLoopCT_label | APEtype | APEdihe_label | APEdist_label | APE10_dihe_label | APE10 φ,ψ | APE9_dihe_label | APE9 φ,ψ | APE8_dihe_label | APE8 φ,ψ | APE8_rotamer_label | APE8 χ1 | APE67_label | APE6 φ,ψ | APE7 φ,ψ | APE12_dist_label | APE12_DFG4_dis | APE11_dist_label | APE11_DFG4_dis | APE10_dist_label | APE10_DFG4_dis | APE9_dist_label | APE9_Arg_dis | Chain_mut | Chain_phos | Modified_aa | Method | Resolution | Rvalue | FreeRvalue | Chain_id | ChainLen | Ordered_residues | DomainBreak | ActLoopLength | ActLoopResolvedResidues | ActLoopDisorderedResidues | Kinase_domains_Unp | N_Kinase_domains_Unp | pdb | Species | Kincore_name | hmm | Evalue | Score | hmmbeg | hmmend | hmmlen | XDFGnum | DFGnum | PHEnum | DFG4num | DFG6num | LYSnum | GLUnum | GLU4num | XHRDnum | ARGnum | HRDnum | HRDaspnum | aFaspnum | APEnum | APE6num | APE7num | APE8num | APE9num | APE10num | APE11num | APE12num | Hinge1num | Protein_name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| TYR | PTK6 | PTK6_HUMAN | 5H2UA | Q13882 | 185 | 446 | 451.0 | 1N1:60501 | Type1 | Inactive | DFGin | 5.9983 | 13.4628 | BLBplus | -115.66, 172.2 | 65.44, 13.7 | -58.08, 130.19 | 47.49, 85.54 | 66.94, -1.55 | out-out | out | 14.1683 | Saltbr-out | 16.091 | HRD-in | -72.57, -54.48 | 85.53, -13.44 | out-out-out | SNCooo | out-out | ActLoopNT-out | 7.2608 | ActLoopCT-out | TYR | APEdihe_oooai | APEdist_aaao | APE10-dihe-out | 72.03, 33.67 | APE9-dihe-out | -55.65, -32.62 | APE8-dihe-out | -63.18, -18.16 | APE8-rot-na | 340.69 | APE67-dihe-in | -82.41, -18.93 | -56.57, -27.65 | APE12-dist-na | 16.3439 | APE11-dist-na | 20.6081 | APE10-dist-na | 18.2629 | APE9-dist-out | 11.0621 | C433T | None | None | XRAY | 2.24 | 0.208 | 0.26 | A | 267.0 | 261.0 | 1 | 28 | 28 | 0 | [[191, 443]] | 1.0 | 5h2u | Homo sapiens | TYR_PTK6_HUMAN | TYR | 9.8e-89 | 303.0 | 2.0 | 260.0 | 259.0 | 329 | 330 | 331 | 333 | 335 | 219 | 235 | 239 | 309 | 311 | 310 | 312.0 | 369 | 357 | 352 | 351 | 350 | 349 | 348 | 347 | 346 | 265 | Protein-tyrosine kinase 6 |
| TYR | PTK6 | PTK6_HUMAN | 5H2UB | Q13882 | 185 | 446 | 451.0 | 1N1:60501 | Type1 | Inactive | DFGin | 6.0808 | 13.3427 | BLBplus | -112.62, 168.56 | 69.96, 13.64 | -58.15, 126.09 | 44.9, 88.52 | 70.74, 0.77 | out-out | out | 14.3036 | Saltbr-out | 15.9567 | HRD-in | -65.56, -52.22 | 84.8, -15.83 | out-out-out | SNCooo | out-out | ActLoopNT-out | 7.0671 | ActLoopCT-out | TYR | APEdihe_oooai | APEdist_aaao | APE10-dihe-out | 67.1, 31.04 | APE9-dihe-out | -51.48, -32.62 | APE8-dihe-out | -56.92, -21.84 | APE8-rot-na | 331.92 | APE67-dihe-in | -82.05, -11.15 | -61.67, -25.37 | APE12-dist-na | 16.2609 | APE11-dist-na | 20.2262 | APE10-dist-na | 17.9045 | APE9-dist-out | 11.0552 | C433T | None | None | XRAY | 2.24 | 0.208 | 0.26 | B | 267.0 | 261.0 | 1 | 28 | 28 | 0 | [[191, 443]] | 1.0 | 5h2u | Homo sapiens | TYR_PTK6_HUMAN | TYR | 9.8e-89 | 303.0 | 2.0 | 260.0 | 259.0 | 329 | 330 | 331 | 333 | 335 | 219 | 235 | 239 | 309 | 311 | 310 | 312.0 | 369 | 357 | 352 | 351 | 350 | 349 | 348 | 347 | 346 | 265 | Protein-tyrosine kinase 6 |
| TYR | PTK6 | PTK6_HUMAN | 5H2UC | Q13882 | 185 | 446 | 451.0 | 1N1:60501 | Type1 | Inactive | DFGin | 5.9677 | 13.6341 | BLBplus | -101.49, 165.12 | 71.33, 11.9 | -56.7, 126.68 | 46.28, 85.99 | 72.45, -1.55 | out-out | out | 14.2504 | Saltbr-out | 15.3617 | HRD-in | -69.3, -53.89 | 83.99, -9.53 | out-out-out | SNCooo | out-out | ActLoopNT-out | 7.1583 | ActLoopCT-out | TYR | APEdihe_oooai | APEdist_aaao | APE10-dihe-out | 66.45, 29.68 | APE9-dihe-out | -47.22, -37.04 | APE8-dihe-out | -58.56, -24.03 | APE8-rot-na | 334.48 | APE67-dihe-in | -84.14, -9.31 | -53.24, -25.76 | APE12-dist-na | 16.3889 | APE11-dist-na | 20.3117 | APE10-dist-na | 17.9592 | APE9-dist-out | 11.0174 | C433T | None | None | XRAY | 2.24 | 0.208 | 0.26 | C | 267.0 | 261.0 | 1 | 28 | 28 | 0 | [[191, 443]] | 1.0 | 5h2u | Homo sapiens | TYR_PTK6_HUMAN | TYR | 9.8e-89 | 303.0 | 2.0 | 260.0 | 259.0 | 329 | 330 | 331 | 333 | 335 | 219 | 235 | 239 | 309 | 311 | 310 | 312.0 | 369 | 357 | 352 | 351 | 350 | 349 | 348 | 347 | 346 | 265 | Protein-tyrosine kinase 6 |
| TYR | PTK6 | PTK6_HUMAN | 5H2UD | Q13882 | 185 | 446 | 451.0 | 1N1:60504 | Type1 | Inactive | DFGin | 6.1814 | 13.2695 | BLBplus | -112.73, 164.13 | 73.65, 11.67 | -56.94, 123.73 | 42.41, 88.79 | 73.17, 2.96 | out-out | out | 14.0107 | Saltbr-out | 15.9929 | HRD-in | -70.19, -55.11 | 88.71, -18.22 | out-out-out | SNCooo | out-out | ActLoopNT-out | 7.1947 | ActLoopCT-out | TYR | APEdihe_oooai | APEdist_aaao | APE10-dihe-out | 72.07, 30.74 | APE9-dihe-out | -48.72, -36.76 | APE8-dihe-out | -61.03, -20.74 | APE8-rot-na | 334.99 | APE67-dihe-in | -84.77, -13.01 | -55.36, -26.11 | APE12-dist-na | 16.3004 | APE11-dist-na | 20.346 | APE10-dist-na | 18.0251 | APE9-dist-out | 11.0324 | C433T | None | None | XRAY | 2.24 | 0.208 | 0.26 | D | 267.0 | 261.0 | 1 | 28 | 28 | 0 | [[191, 443]] | 1.0 | 5h2u | Homo sapiens | TYR_PTK6_HUMAN | TYR | 9.8e-89 | 303.0 | 2.0 | 260.0 | 259.0 | 329 | 330 | 331 | 333 | 335 | 219 | 235 | 239 | 309 | 311 | 310 | 312.0 | 369 | 357 | 352 | 351 | 350 | 349 | 348 | 347 | 346 | 265 | Protein-tyrosine kinase 6 |
| Spatial label | Dihedral label | Number of Chains | Percent | Representative |
|---|
| Group | Gene | SwissprotID | PDB | UniprotID | First_obs_res | Last_obs_res | Length_Unp | Ligand | Ligand_type | Activity_label | Spatial_label | Phe_Glu4_dis | Phe_Lys_dis | Dihedral_label | XDFG φ,ψ |
DFG-Asp φ,ψ |
DFG-Phe φ,ψ |
DFG-Phe χ1,χ2 |
DFG-Gly φ,ψ |
ChelixSaltbr_label | Chelix_label | Lys_Glu_dis | Saltbr_label | LysNZ_GluOE_dis | HRD_label | His φ,ψ | Arg φ,ψ | SNC_label | SNCpymol_label | ActLoop_label | ActLoopNT_label | DFG6_XHRD_dis | ActLoopCT_label | APEtype | APEdihe_label | APEdist_label | APE10_dihe_label | APE10 φ,ψ | APE9_dihe_label | APE9 φ,ψ | APE8_dihe_label | APE8 φ,ψ | APE8_rotamer_label | APE8 χ1 | APE67_label | APE6 φ,ψ | APE7 φ,ψ | APE12_dist_label | APE12_DFG4_dis | APE11_dist_label | APE11_DFG4_dis | APE10_dist_label | APE10_DFG4_dis | APE9_dist_label | APE9_Arg_dis | Chain_mut | Chain_phos | Modified_aa | Method | Resolution | Rvalue | FreeRvalue | Chain_id | ChainLen | Ordered_residues | DomainBreak | ActLoopLength | ActLoopResolvedResidues | ActLoopDisorderedResidues | Kinase_domains_Unp | N_Kinase_domains_Unp | pdb | Species | Kincore_name | hmm | Evalue | Score | hmmbeg | hmmend | hmmlen | XDFGnum | DFGnum | PHEnum | DFG4num | DFG6num | LYSnum | GLUnum | GLU4num | XHRDnum | ARGnum | HRDnum | HRDaspnum | aFaspnum | APEnum | APE6num | APE7num | APE8num | APE9num | APE10num | APE11num | APE12num | Hinge1num | Protein_name |
|---|