PDB: 5FLF — TYR FGFR1_HUMAN

Total number of chains: 5
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 4 80.0% 5FLFA
DFGin BLAplus 1 20.0% 5FLFE
All chains - renumbered by
Uniprot PDB Alignment

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Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR FGFR1 FGFR1_HUMAN 5FLFA P11362 460 762 822.0 No_ligand No_ligand Inactive DFGin 6.566 13.921 BLAminus -130.07, -173.3 57.53, 81.51 -106.56, 20.58 287.47, 88.65 -65.69, -26.36 in-in in 7.061 Saltbr-in 2.623 HRD-in -77.09, -44.33 71.36, -17.68 in-in-out SNCiio in-out ActLoopNT-in 2.874 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -122.27, 31.65 APE9-dihe-in -120.82, 141.16 APE8-dihe-in -55.6, 118.0 APE8-rot-na 17.74 APE67-dihe-in -68.76, -3.74 -51.76, -42.09 APE12-dist-na 14.969 APE11-dist-na 10.487 APE10-dist-na 8.045 APE9-dist-in 5.76 R675G None None XRAY 2.58 0.197 0.255 A 310 296 7 0 0 0 [[478, 756]] 1.0 5flf TYR_FGFR1_HUMAN TYR 2.7e-104 354.0 1 260 260 640 641 642 644 646 514 531 535 620 622 621 623 682 670 665 664 663 662 661 660 659 562 Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 5FLFB P11362 460 764 822.0 No_ligand No_ligand Inactive DFGin 6.597 14.271 BLAminus -131.38, -174.56 57.69, 69.98 -91.26, 21.65 284.1, 89.91 -69.58, -18.15 in-in in 7.208 Saltbr-in 2.661 HRD-in -77.24, -42.46 70.08, -13.13 in-in-out SNCiio in-out ActLoopNT-in 2.95 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -119.34, 21.86 APE9-dihe-in -108.05, 143.02 APE8-dihe-in -54.9, 122.45 APE8-rot-na 333.47 APE67-dihe-in -66.56, -8.26 -58.19, -40.45 APE12-dist-na 14.767 APE11-dist-na 10.342 APE10-dist-na 7.676 APE9-dist-in 5.588 R675G None None XRAY 2.58 0.197 0.255 B 310 292 13 0 0 0 [[478, 756]] 1.0 5flf TYR_FGFR1_HUMAN TYR 2.7e-104 354.0 1 260 260 640 641 642 644 646 514 531 535 620 622 621 623 682 670 665 664 663 662 661 660 659 562 Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 5FLFC P11362 464 763 822.0 No_ligand No_ligand Inactive DFGin 6.879 14.904 BLAminus -128.63, -179.22 56.68, 76.02 -97.55, 23.96 288.87, 80.23 -64.42, -24.4 in-in in 7.867 Saltbr-in 2.593 HRD-in -77.84, -41.46 68.92, -13.37 in-in-out SNCiio in-out ActLoopNT-in 3.012 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -113.74, 13.42 APE9-dihe-in -108.0, 146.11 APE8-dihe-in -55.87, 118.95 APE8-rot-na 334.41 APE67-dihe-in -77.03, -3.15 -66.33, -25.17 APE12-dist-na 14.723 APE11-dist-na 11.018 APE10-dist-na 8.04 APE9-dist-in 5.535 R675G None None XRAY 2.58 0.197 0.255 C 310 283 17 0 0 0 [[478, 756]] 1.0 5flf TYR_FGFR1_HUMAN TYR 2.7e-104 354.0 1 260 260 640 641 642 644 646 514 531 535 620 622 621 623 682 670 665 664 663 662 661 660 659 562 Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 5FLFD P11362 465 763 822.0 No_ligand No_ligand Inactive DFGin 6.563 14.075 BLAminus -137.61, -174.47 56.6, 77.52 -99.56, 24.88 289.94, 80.48 -64.3, -28.41 in-in in 7.277 Saltbr-in 2.824 HRD-in -82.09, -46.03 69.99, -9.21 in-in-out SNCiio in-out ActLoopNT-in 2.934 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -123.36, 26.56 APE9-dihe-in -112.27, 140.35 APE8-dihe-in -53.21, 117.11 APE8-rot-na 330.63 APE67-dihe-in -75.55, -3.28 -53.96, -35.33 APE12-dist-na 14.943 APE11-dist-na 10.506 APE10-dist-na 7.993 APE9-dist-in 5.598 R675G None None XRAY 2.58 0.197 0.255 D 310 290 9 0 0 0 [[478, 756]] 1.0 5flf TYR_FGFR1_HUMAN TYR 2.7e-104 354.0 1 260 260 640 641 642 644 646 514 531 535 620 622 621 623 682 670 665 664 663 662 661 660 659 562 Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 5FLFE P11362 466 761 822.0 No_ligand No_ligand Inactive DFGin 5.857 13.333 BLAplus -107.08, 156.12 59.3, 89.04 -145.68, 9.21 46.94, 85.34 -107.07, -8.42 in-out in 7.681 Saltbr-out 4.122 HRD-in -76.44, -47.72 79.39, -32.07 out-none-out SNCono none-out ActLoopNT-none 999.0 ActLoopCT-out TYR APEdihe_iooai APEdist_aaao APE10-dihe-in -134.53, 84.16 APE9-dihe-out 70.54, 76.98 APE8-dihe-out -73.71, -15.89 APE8-rot-na 29.38 APE67-dihe-in -66.59, -10.19 -60.2, -29.73 APE12-dist-na 999.0 APE11-dist-na 15.329 APE10-dist-na 19.628 APE9-dist-out 11.396 R675G None None XRAY 2.58 0.197 0.255 E 310 258 38 0 0 14 [[478, 756]] 1.0 5flf TYR_FGFR1_HUMAN TYR 2.7e-104 354.0 1 260 260 640 641 642 644 646 514 531 535 620 622 621 623 682 670 665 664 663 662 661 660 659 562 Fibroblast growth factor receptor 1

PDB: 5FLF — TYR FGFR1_HUMAN

Total number of chains: 5
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 4 80.0% 5FLFA
DFGin BLAplus 1 20.0% 5FLFE
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR FGFR1 FGFR1_HUMAN 5FLFA P11362 460 762 822.0 No_ligand No_ligand Inactive DFGin 6.566 13.921 BLAminus -130.07, -173.3 57.53, 81.51 -106.56, 20.58 287.47, 88.65 -65.69, -26.36 in-in in 7.061 Saltbr-in 2.623 HRD-in -77.09, -44.33 71.36, -17.68 in-in-out SNCiio in-out ActLoopNT-in 2.874 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -122.27, 31.65 APE9-dihe-in -120.82, 141.16 APE8-dihe-in -55.6, 118.0 APE8-rot-na 17.74 APE67-dihe-in -68.76, -3.74 -51.76, -42.09 APE12-dist-na 14.969 APE11-dist-na 10.487 APE10-dist-na 8.045 APE9-dist-in 5.76 R675G None None XRAY 2.58 0.197 0.255 A 310 296 7 0 0 0 [[478, 756]] 1.0 5flf Homo sapiens TYR_FGFR1_HUMAN TYR 2.7e-104 354.0 1 260 260 640 641 642 644 646 514 531 535 620 622 621 623 682 670 665 664 663 662 661 660 659 562 Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 5FLFB P11362 460 764 822.0 No_ligand No_ligand Inactive DFGin 6.597 14.271 BLAminus -131.38, -174.56 57.69, 69.98 -91.26, 21.65 284.1, 89.91 -69.58, -18.15 in-in in 7.208 Saltbr-in 2.661 HRD-in -77.24, -42.46 70.08, -13.13 in-in-out SNCiio in-out ActLoopNT-in 2.95 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -119.34, 21.86 APE9-dihe-in -108.05, 143.02 APE8-dihe-in -54.9, 122.45 APE8-rot-na 333.47 APE67-dihe-in -66.56, -8.26 -58.19, -40.45 APE12-dist-na 14.767 APE11-dist-na 10.342 APE10-dist-na 7.676 APE9-dist-in 5.588 R675G None None XRAY 2.58 0.197 0.255 B 310 292 13 0 0 0 [[478, 756]] 1.0 5flf Homo sapiens TYR_FGFR1_HUMAN TYR 2.7e-104 354.0 1 260 260 640 641 642 644 646 514 531 535 620 622 621 623 682 670 665 664 663 662 661 660 659 562 Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 5FLFC P11362 464 763 822.0 No_ligand No_ligand Inactive DFGin 6.879 14.904 BLAminus -128.63, -179.22 56.68, 76.02 -97.55, 23.96 288.87, 80.23 -64.42, -24.4 in-in in 7.867 Saltbr-in 2.593 HRD-in -77.84, -41.46 68.92, -13.37 in-in-out SNCiio in-out ActLoopNT-in 3.012 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -113.74, 13.42 APE9-dihe-in -108.0, 146.11 APE8-dihe-in -55.87, 118.95 APE8-rot-na 334.41 APE67-dihe-in -77.03, -3.15 -66.33, -25.17 APE12-dist-na 14.723 APE11-dist-na 11.018 APE10-dist-na 8.04 APE9-dist-in 5.535 R675G None None XRAY 2.58 0.197 0.255 C 310 283 17 0 0 0 [[478, 756]] 1.0 5flf Homo sapiens TYR_FGFR1_HUMAN TYR 2.7e-104 354.0 1 260 260 640 641 642 644 646 514 531 535 620 622 621 623 682 670 665 664 663 662 661 660 659 562 Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 5FLFD P11362 465 763 822.0 No_ligand No_ligand Inactive DFGin 6.563 14.075 BLAminus -137.61, -174.47 56.6, 77.52 -99.56, 24.88 289.94, 80.48 -64.3, -28.41 in-in in 7.277 Saltbr-in 2.824 HRD-in -82.09, -46.03 69.99, -9.21 in-in-out SNCiio in-out ActLoopNT-in 2.934 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -123.36, 26.56 APE9-dihe-in -112.27, 140.35 APE8-dihe-in -53.21, 117.11 APE8-rot-na 330.63 APE67-dihe-in -75.55, -3.28 -53.96, -35.33 APE12-dist-na 14.943 APE11-dist-na 10.506 APE10-dist-na 7.993 APE9-dist-in 5.598 R675G None None XRAY 2.58 0.197 0.255 D 310 290 9 0 0 0 [[478, 756]] 1.0 5flf Homo sapiens TYR_FGFR1_HUMAN TYR 2.7e-104 354.0 1 260 260 640 641 642 644 646 514 531 535 620 622 621 623 682 670 665 664 663 662 661 660 659 562 Fibroblast growth factor receptor 1
TYR FGFR1 FGFR1_HUMAN 5FLFE P11362 466 761 822.0 No_ligand No_ligand Inactive DFGin 5.857 13.333 BLAplus -107.08, 156.12 59.3, 89.04 -145.68, 9.21 46.94, 85.34 -107.07, -8.42 in-out in 7.681 Saltbr-out 4.122 HRD-in -76.44, -47.72 79.39, -32.07 out-none-out SNCono none-out ActLoopNT-none 999.0 ActLoopCT-out TYR APEdihe_iooai APEdist_aaao APE10-dihe-in -134.53, 84.16 APE9-dihe-out 70.54, 76.98 APE8-dihe-out -73.71, -15.89 APE8-rot-na 29.38 APE67-dihe-in -66.59, -10.19 -60.2, -29.73 APE12-dist-na 999.0 APE11-dist-na 15.329 APE10-dist-na 19.628 APE9-dist-out 11.396 R675G None None XRAY 2.58 0.197 0.255 E 310 258 38 0 0 14 [[478, 756]] 1.0 5flf Homo sapiens TYR_FGFR1_HUMAN TYR 2.7e-104 354.0 1 260 260 640 641 642 644 646 514 531 535 620 622 621 623 682 670 665 664 663 662 661 660 659 562 Fibroblast growth factor receptor 1

PDB: 5FLF — TYR FGFR1_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name