| Group | Gene | SwissprotID | PDB | UniprotID | First_obs_res | Last_obs_res | Length_Unp | Ligand | Ligand_type | Activity_label | Spatial_label | Phe_Glu4_dis | Phe_Lys_dis | Dihedral_label | XDFG φ,ψ |
DFG-Asp φ,ψ |
DFG-Phe φ,ψ |
DFG-Phe χ1,χ2 |
DFG-Gly φ,ψ |
ChelixSaltbr_label | Chelix_label | Lys_Glu_dis | Saltbr_label | LysNZ_GluOE_dis | HRD_label | His φ,ψ | Arg φ,ψ | SNC_label | SNCpymol_label | ActLoop_label | ActLoopNT_label | DFG6_XHRD_dis | ActLoopCT_label | APEtype | APEdihe_label | APEdist_label | APE10_dihe_label | APE10 φ,ψ | APE9_dihe_label | APE9 φ,ψ | APE8_dihe_label | APE8 φ,ψ | APE8_rotamer_label | APE8 χ1 | APE67_label | APE6 φ,ψ | APE7 φ,ψ | APE12_dist_label | APE12_DFG4_dis | APE11_dist_label | APE11_DFG4_dis | APE10_dist_label | APE10_DFG4_dis | APE9_dist_label | APE9_Arg_dis | Chain_mut | Chain_phos | Modified_aa | Method | Resolution | Rvalue | FreeRvalue | Chain_id | ChainLen | Ordered_residues | DomainBreak | ActLoopLength | ActLoopResolvedResidues | ActLoopDisorderedResidues | Kinase_domains_Unp | N_Kinase_domains_Unp | pdb | Kincore_name | hmm | Evalue | Score | hmmbeg | hmmend | hmmlen | XDFGnum | DFGnum | PHEnum | DFG4num | DFG6num | LYSnum | GLUnum | GLU4num | XHRDnum | ARGnum | HRDnum | HRDaspnum | aFaspnum | APEnum | APE6num | APE7num | APE8num | APE9num | APE10num | APE11num | APE12num | Hinge1num | Protein_name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| TYR | PTK6 | PTK6_HUMAN | 5D7VA | Q13882 | 185 | 446 | 451.0 | No_ligand | No_ligand | Inactive | DFGin | 6.1388 | 13.5533 | BLBplus | -121.2, 164.97 | 61.69, 29.26 | -66.74, 129.56 | 42.93, 87.49 | 71.64, 0.22 | out-out | out | 14.4616 | Saltbr-out | 16.4453 | HRD-in | -62.55, -53.11 | 84.63, -9.09 | out-out-out | SNCooo | out-out | ActLoopNT-out | 6.9322 | ActLoopCT-out | TYR | APEdihe_oooai | APEdist_aaao | APE10-dihe-out | 74.52, 33.07 | APE9-dihe-out | -59.56, -34.19 | APE8-dihe-out | -55.32, -17.26 | APE8-rot-na | 330.79 | APE67-dihe-in | -89.93, -14.57 | -63.75, -21.53 | APE12-dist-na | 16.2464 | APE11-dist-na | 20.5123 | APE10-dist-na | 18.297 | APE9-dist-out | 11.1969 | C433T | None | None | XRAY | 2.33 | 0.222 | 0.282 | A | 269.0 | 262.0 | 0 | 28 | 28 | 0 | [[191, 443]] | 1.0 | 5d7v | TYR_PTK6_HUMAN | TYR | 1e-88 | 303.0 | 2.0 | 260.0 | 259.0 | 329 | 330 | 331 | 333 | 335 | 219 | 235 | 239 | 309 | 311 | 310 | 312.0 | 369 | 357 | 352 | 351 | 350 | 349 | 348 | 347 | 346 | 265 | Protein-tyrosine kinase 6 |
| TYR | PTK6 | PTK6_HUMAN | 5D7VB | Q13882 | 185 | 446 | 451.0 | No_ligand | No_ligand | Inactive | DFGin | 6.399 | 13.6137 | BLBplus | -123.86, 157.2 | 63.47, 26.61 | -58.96, 130.91 | 40.81, 91.33 | 77.41, -12.9 | out-out | out | 14.3973 | Saltbr-out | 16.2798 | HRD-in | -63.86, -55.35 | 86.02, -13.31 | out-out-out | SNCooo | out-out | ActLoopNT-out | 6.9145 | ActLoopCT-out | TYR | APEdihe_oooai | APEdist_aaao | APE10-dihe-out | 77.62, 30.35 | APE9-dihe-out | -52.55, -33.08 | APE8-dihe-out | -58.94, -22.44 | APE8-rot-na | 334.64 | APE67-dihe-in | -88.77, -14.43 | -61.89, -18.59 | APE12-dist-na | 16.2364 | APE11-dist-na | 20.1871 | APE10-dist-na | 17.9997 | APE9-dist-out | 10.8822 | C433T | None | None | XRAY | 2.33 | 0.222 | 0.282 | B | 269.0 | 262.0 | 0 | 28 | 28 | 0 | [[191, 443]] | 1.0 | 5d7v | TYR_PTK6_HUMAN | TYR | 1e-88 | 303.0 | 2.0 | 260.0 | 259.0 | 329 | 330 | 331 | 333 | 335 | 219 | 235 | 239 | 309 | 311 | 310 | 312.0 | 369 | 357 | 352 | 351 | 350 | 349 | 348 | 347 | 346 | 265 | Protein-tyrosine kinase 6 |
| TYR | PTK6 | PTK6_HUMAN | 5D7VC | Q13882 | 185 | 446 | 451.0 | No_ligand | No_ligand | Inactive | DFGin | 6.1395 | 13.7756 | BLBplus | -115.2, 156.93 | 69.87, 24.94 | -59.08, 133.85 | 39.69, 88.1 | 65.42, 1.58 | out-out | out | 14.5615 | Saltbr-out | 17.12 | HRD-in | -66.64, -48.83 | 82.22, -12.69 | out-out-out | SNCooo | out-out | ActLoopNT-out | 6.8905 | ActLoopCT-out | TYR | APEdihe_oooai | APEdist_aaao | APE10-dihe-out | 68.7, 30.95 | APE9-dihe-out | -52.49, -33.1 | APE8-dihe-out | -62.5, -15.14 | APE8-rot-na | 336.42 | APE67-dihe-in | -89.66, -14.58 | -61.06, -20.95 | APE12-dist-na | 16.3526 | APE11-dist-na | 20.3075 | APE10-dist-na | 18.0709 | APE9-dist-out | 11.0351 | C433T | None | None | XRAY | 2.33 | 0.222 | 0.282 | C | 269.0 | 262.0 | 0 | 28 | 28 | 0 | [[191, 443]] | 1.0 | 5d7v | TYR_PTK6_HUMAN | TYR | 1e-88 | 303.0 | 2.0 | 260.0 | 259.0 | 329 | 330 | 331 | 333 | 335 | 219 | 235 | 239 | 309 | 311 | 310 | 312.0 | 369 | 357 | 352 | 351 | 350 | 349 | 348 | 347 | 346 | 265 | Protein-tyrosine kinase 6 |
| TYR | PTK6 | PTK6_HUMAN | 5D7VD | Q13882 | 185 | 446 | 451.0 | No_ligand | No_ligand | Inactive | DFGin | 6.3702 | 13.5241 | BLBplus | -117.16, 161.19 | 62.88, 23.36 | -54.86, 120.63 | 38.18, 87.07 | 76.37, -1.14 | out-out | out | 14.3618 | Saltbr-out | 15.8385 | HRD-in | -69.27, -47.17 | 79.0, -19.12 | out-out-out | SNCooo | out-out | ActLoopNT-out | 7.0147 | ActLoopCT-out | TYR | APEdihe_oooai | APEdist_aaao | APE10-dihe-out | 70.93, 30.38 | APE9-dihe-out | -56.79, -33.98 | APE8-dihe-out | -54.5, -20.93 | APE8-rot-na | 331.77 | APE67-dihe-in | -86.43, -14.83 | -61.32, -24.75 | APE12-dist-na | 16.1621 | APE11-dist-na | 20.1821 | APE10-dist-na | 18.1792 | APE9-dist-out | 10.9634 | C433T | None | None | XRAY | 2.33 | 0.222 | 0.282 | D | 269.0 | 262.0 | 0 | 28 | 28 | 0 | [[191, 443]] | 1.0 | 5d7v | TYR_PTK6_HUMAN | TYR | 1e-88 | 303.0 | 2.0 | 260.0 | 259.0 | 329 | 330 | 331 | 333 | 335 | 219 | 235 | 239 | 309 | 311 | 310 | 312.0 | 369 | 357 | 352 | 351 | 350 | 349 | 348 | 347 | 346 | 265 | Protein-tyrosine kinase 6 |
| Group | Gene | SwissprotID | PDB | UniprotID | First_obs_res | Last_obs_res | Length_Unp | Ligand | Ligand_type | Activity_label | Spatial_label | Phe_Glu4_dis | Phe_Lys_dis | Dihedral_label | XDFG φ,ψ |
DFG-Asp φ,ψ |
DFG-Phe φ,ψ |
DFG-Phe χ1,χ2 |
DFG-Gly φ,ψ |
ChelixSaltbr_label | Chelix_label | Lys_Glu_dis | Saltbr_label | LysNZ_GluOE_dis | HRD_label | His φ,ψ | Arg φ,ψ | SNC_label | SNCpymol_label | ActLoop_label | ActLoopNT_label | DFG6_XHRD_dis | ActLoopCT_label | APEtype | APEdihe_label | APEdist_label | APE10_dihe_label | APE10 φ,ψ | APE9_dihe_label | APE9 φ,ψ | APE8_dihe_label | APE8 φ,ψ | APE8_rotamer_label | APE8 χ1 | APE67_label | APE6 φ,ψ | APE7 φ,ψ | APE12_dist_label | APE12_DFG4_dis | APE11_dist_label | APE11_DFG4_dis | APE10_dist_label | APE10_DFG4_dis | APE9_dist_label | APE9_Arg_dis | Chain_mut | Chain_phos | Modified_aa | Method | Resolution | Rvalue | FreeRvalue | Chain_id | ChainLen | Ordered_residues | DomainBreak | ActLoopLength | ActLoopResolvedResidues | ActLoopDisorderedResidues | Kinase_domains_Unp | N_Kinase_domains_Unp | pdb | Species | Kincore_name | hmm | Evalue | Score | hmmbeg | hmmend | hmmlen | XDFGnum | DFGnum | PHEnum | DFG4num | DFG6num | LYSnum | GLUnum | GLU4num | XHRDnum | ARGnum | HRDnum | HRDaspnum | aFaspnum | APEnum | APE6num | APE7num | APE8num | APE9num | APE10num | APE11num | APE12num | Hinge1num | Protein_name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| TYR | PTK6 | PTK6_HUMAN | 5D7VA | Q13882 | 185 | 446 | 451.0 | No_ligand | No_ligand | Inactive | DFGin | 6.1388 | 13.5533 | BLBplus | -121.2, 164.97 | 61.69, 29.26 | -66.74, 129.56 | 42.93, 87.49 | 71.64, 0.22 | out-out | out | 14.4616 | Saltbr-out | 16.4453 | HRD-in | -62.55, -53.11 | 84.63, -9.09 | out-out-out | SNCooo | out-out | ActLoopNT-out | 6.9322 | ActLoopCT-out | TYR | APEdihe_oooai | APEdist_aaao | APE10-dihe-out | 74.52, 33.07 | APE9-dihe-out | -59.56, -34.19 | APE8-dihe-out | -55.32, -17.26 | APE8-rot-na | 330.79 | APE67-dihe-in | -89.93, -14.57 | -63.75, -21.53 | APE12-dist-na | 16.2464 | APE11-dist-na | 20.5123 | APE10-dist-na | 18.297 | APE9-dist-out | 11.1969 | C433T | None | None | XRAY | 2.33 | 0.222 | 0.282 | A | 269.0 | 262.0 | 0 | 28 | 28 | 0 | [[191, 443]] | 1.0 | 5d7v | Homo sapiens | TYR_PTK6_HUMAN | TYR | 1e-88 | 303.0 | 2.0 | 260.0 | 259.0 | 329 | 330 | 331 | 333 | 335 | 219 | 235 | 239 | 309 | 311 | 310 | 312.0 | 369 | 357 | 352 | 351 | 350 | 349 | 348 | 347 | 346 | 265 | Protein-tyrosine kinase 6 |
| TYR | PTK6 | PTK6_HUMAN | 5D7VB | Q13882 | 185 | 446 | 451.0 | No_ligand | No_ligand | Inactive | DFGin | 6.399 | 13.6137 | BLBplus | -123.86, 157.2 | 63.47, 26.61 | -58.96, 130.91 | 40.81, 91.33 | 77.41, -12.9 | out-out | out | 14.3973 | Saltbr-out | 16.2798 | HRD-in | -63.86, -55.35 | 86.02, -13.31 | out-out-out | SNCooo | out-out | ActLoopNT-out | 6.9145 | ActLoopCT-out | TYR | APEdihe_oooai | APEdist_aaao | APE10-dihe-out | 77.62, 30.35 | APE9-dihe-out | -52.55, -33.08 | APE8-dihe-out | -58.94, -22.44 | APE8-rot-na | 334.64 | APE67-dihe-in | -88.77, -14.43 | -61.89, -18.59 | APE12-dist-na | 16.2364 | APE11-dist-na | 20.1871 | APE10-dist-na | 17.9997 | APE9-dist-out | 10.8822 | C433T | None | None | XRAY | 2.33 | 0.222 | 0.282 | B | 269.0 | 262.0 | 0 | 28 | 28 | 0 | [[191, 443]] | 1.0 | 5d7v | Homo sapiens | TYR_PTK6_HUMAN | TYR | 1e-88 | 303.0 | 2.0 | 260.0 | 259.0 | 329 | 330 | 331 | 333 | 335 | 219 | 235 | 239 | 309 | 311 | 310 | 312.0 | 369 | 357 | 352 | 351 | 350 | 349 | 348 | 347 | 346 | 265 | Protein-tyrosine kinase 6 |
| TYR | PTK6 | PTK6_HUMAN | 5D7VC | Q13882 | 185 | 446 | 451.0 | No_ligand | No_ligand | Inactive | DFGin | 6.1395 | 13.7756 | BLBplus | -115.2, 156.93 | 69.87, 24.94 | -59.08, 133.85 | 39.69, 88.1 | 65.42, 1.58 | out-out | out | 14.5615 | Saltbr-out | 17.12 | HRD-in | -66.64, -48.83 | 82.22, -12.69 | out-out-out | SNCooo | out-out | ActLoopNT-out | 6.8905 | ActLoopCT-out | TYR | APEdihe_oooai | APEdist_aaao | APE10-dihe-out | 68.7, 30.95 | APE9-dihe-out | -52.49, -33.1 | APE8-dihe-out | -62.5, -15.14 | APE8-rot-na | 336.42 | APE67-dihe-in | -89.66, -14.58 | -61.06, -20.95 | APE12-dist-na | 16.3526 | APE11-dist-na | 20.3075 | APE10-dist-na | 18.0709 | APE9-dist-out | 11.0351 | C433T | None | None | XRAY | 2.33 | 0.222 | 0.282 | C | 269.0 | 262.0 | 0 | 28 | 28 | 0 | [[191, 443]] | 1.0 | 5d7v | Homo sapiens | TYR_PTK6_HUMAN | TYR | 1e-88 | 303.0 | 2.0 | 260.0 | 259.0 | 329 | 330 | 331 | 333 | 335 | 219 | 235 | 239 | 309 | 311 | 310 | 312.0 | 369 | 357 | 352 | 351 | 350 | 349 | 348 | 347 | 346 | 265 | Protein-tyrosine kinase 6 |
| TYR | PTK6 | PTK6_HUMAN | 5D7VD | Q13882 | 185 | 446 | 451.0 | No_ligand | No_ligand | Inactive | DFGin | 6.3702 | 13.5241 | BLBplus | -117.16, 161.19 | 62.88, 23.36 | -54.86, 120.63 | 38.18, 87.07 | 76.37, -1.14 | out-out | out | 14.3618 | Saltbr-out | 15.8385 | HRD-in | -69.27, -47.17 | 79.0, -19.12 | out-out-out | SNCooo | out-out | ActLoopNT-out | 7.0147 | ActLoopCT-out | TYR | APEdihe_oooai | APEdist_aaao | APE10-dihe-out | 70.93, 30.38 | APE9-dihe-out | -56.79, -33.98 | APE8-dihe-out | -54.5, -20.93 | APE8-rot-na | 331.77 | APE67-dihe-in | -86.43, -14.83 | -61.32, -24.75 | APE12-dist-na | 16.1621 | APE11-dist-na | 20.1821 | APE10-dist-na | 18.1792 | APE9-dist-out | 10.9634 | C433T | None | None | XRAY | 2.33 | 0.222 | 0.282 | D | 269.0 | 262.0 | 0 | 28 | 28 | 0 | [[191, 443]] | 1.0 | 5d7v | Homo sapiens | TYR_PTK6_HUMAN | TYR | 1e-88 | 303.0 | 2.0 | 260.0 | 259.0 | 329 | 330 | 331 | 333 | 335 | 219 | 235 | 239 | 309 | 311 | 310 | 312.0 | 369 | 357 | 352 | 351 | 350 | 349 | 348 | 347 | 346 | 265 | Protein-tyrosine kinase 6 |
| Spatial label | Dihedral label | Number of Chains | Percent | Representative |
|---|
| Group | Gene | SwissprotID | PDB | UniprotID | First_obs_res | Last_obs_res | Length_Unp | Ligand | Ligand_type | Activity_label | Spatial_label | Phe_Glu4_dis | Phe_Lys_dis | Dihedral_label | XDFG φ,ψ |
DFG-Asp φ,ψ |
DFG-Phe φ,ψ |
DFG-Phe χ1,χ2 |
DFG-Gly φ,ψ |
ChelixSaltbr_label | Chelix_label | Lys_Glu_dis | Saltbr_label | LysNZ_GluOE_dis | HRD_label | His φ,ψ | Arg φ,ψ | SNC_label | SNCpymol_label | ActLoop_label | ActLoopNT_label | DFG6_XHRD_dis | ActLoopCT_label | APEtype | APEdihe_label | APEdist_label | APE10_dihe_label | APE10 φ,ψ | APE9_dihe_label | APE9 φ,ψ | APE8_dihe_label | APE8 φ,ψ | APE8_rotamer_label | APE8 χ1 | APE67_label | APE6 φ,ψ | APE7 φ,ψ | APE12_dist_label | APE12_DFG4_dis | APE11_dist_label | APE11_DFG4_dis | APE10_dist_label | APE10_DFG4_dis | APE9_dist_label | APE9_Arg_dis | Chain_mut | Chain_phos | Modified_aa | Method | Resolution | Rvalue | FreeRvalue | Chain_id | ChainLen | Ordered_residues | DomainBreak | ActLoopLength | ActLoopResolvedResidues | ActLoopDisorderedResidues | Kinase_domains_Unp | N_Kinase_domains_Unp | pdb | Species | Kincore_name | hmm | Evalue | Score | hmmbeg | hmmend | hmmlen | XDFGnum | DFGnum | PHEnum | DFG4num | DFG6num | LYSnum | GLUnum | GLU4num | XHRDnum | ARGnum | HRDnum | HRDaspnum | aFaspnum | APEnum | APE6num | APE7num | APE8num | APE9num | APE10num | APE11num | APE12num | Hinge1num | Protein_name |
|---|