PDB: 5CF6 — TYR JAK2_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 2 100.0% 5CF6A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR JAK2-2 JAK2_HUMAN 5CF6A O60674 842 1131 1132.0 50O:64000 Type1 Inactive DFGin 6.2938 13.492 ABAminus -104.13, 1.62 -156.18, 144.42 -132.41, 30.68 297.44, 85.19 -58.71, -30.05 in-in in 8.4023 Saltbr-in 2.8025 HRD-in -64.91, -47.46 68.86, -4.67 in-in-in SNCiii in-in ActLoopNT-in 2.7766 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -87.12, 114.93 APE9-dihe-in -87.57, 141.3 APE8-dihe-in -74.44, 75.42 APE8-rot-na 29.19 APE67-dihe-in -80.74, -1.76 -62.41, -25.89 APE12-dist-na 12.7869 APE11-dist-na 12.2786 APE10-dist-na 13.2224 APE9-dist-in 7.8983 None PTR1007,PTR1008 PTR1007,PTR1008 XRAY 2.5 0.187 0.214 A 321.0 287.0 3 31 31 0 [[545, 807], [849, 1125]] 2.0 5cf6 TYR_JAK2-2_HUMAN TYR 3.4e-87 298.0 1.0 260.0 260.0 993 994 995 997 999 882 898 902 973 975 974 976.0 1036 1024 1019 1018 1017 1016 1015 1014 1013 930 Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 5CF6B O60674 839 1132 1132.0 50O:64000 Type1 Inactive DFGin 6.3279 13.5023 ABAminus -102.75, 1.1 -157.33, 143.82 -132.8, 30.05 297.51, 85.67 -59.73, -28.47 in-in in 8.3417 Saltbr-in 2.8321 HRD-in -65.26, -47.89 69.87, -4.78 in-in-in SNCiii in-in ActLoopNT-in 2.7791 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -72.07, 114.0 APE9-dihe-in -116.42, 144.16 APE8-dihe-in -79.24, 65.15 APE8-rot-na 28.53 APE67-dihe-in -81.85, -1.06 -52.72, -29.08 APE12-dist-na 12.2492 APE11-dist-na 10.493 APE10-dist-na 11.5214 APE9-dist-in 7.569 None PTR1007,PTR1008 PTR1007,PTR1008 XRAY 2.5 0.187 0.214 B 321.0 290.0 4 31 31 0 [[545, 807], [849, 1125]] 2.0 5cf6 TYR_JAK2-2_HUMAN TYR 3.4e-87 298.0 1.0 260.0 260.0 993 994 995 997 999 882 898 902 973 975 974 976.0 1036 1024 1019 1018 1017 1016 1015 1014 1013 930 Tyrosine-protein kinase JAK2

PDB: 5CF6 — TYR JAK2_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 2 100.0% 5CF6A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR JAK2-2 JAK2_HUMAN 5CF6A O60674 842 1131 1132.0 50O:64000 Type1 Inactive DFGin 6.2938 13.492 ABAminus -104.13, 1.62 -156.18, 144.42 -132.41, 30.68 297.44, 85.19 -58.71, -30.05 in-in in 8.4023 Saltbr-in 2.8025 HRD-in -64.91, -47.46 68.86, -4.67 in-in-in SNCiii in-in ActLoopNT-in 2.7766 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -87.12, 114.93 APE9-dihe-in -87.57, 141.3 APE8-dihe-in -74.44, 75.42 APE8-rot-na 29.19 APE67-dihe-in -80.74, -1.76 -62.41, -25.89 APE12-dist-na 12.7869 APE11-dist-na 12.2786 APE10-dist-na 13.2224 APE9-dist-in 7.8983 None PTR1007,PTR1008 PTR1007,PTR1008 XRAY 2.5 0.187 0.214 A 321.0 287.0 3 31 31 0 [[545, 807], [849, 1125]] 2.0 5cf6 Homo sapiens TYR_JAK2-2_HUMAN TYR 3.4e-87 298.0 1.0 260.0 260.0 993 994 995 997 999 882 898 902 973 975 974 976.0 1036 1024 1019 1018 1017 1016 1015 1014 1013 930 Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 5CF6B O60674 839 1132 1132.0 50O:64000 Type1 Inactive DFGin 6.3279 13.5023 ABAminus -102.75, 1.1 -157.33, 143.82 -132.8, 30.05 297.51, 85.67 -59.73, -28.47 in-in in 8.3417 Saltbr-in 2.8321 HRD-in -65.26, -47.89 69.87, -4.78 in-in-in SNCiii in-in ActLoopNT-in 2.7791 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -72.07, 114.0 APE9-dihe-in -116.42, 144.16 APE8-dihe-in -79.24, 65.15 APE8-rot-na 28.53 APE67-dihe-in -81.85, -1.06 -52.72, -29.08 APE12-dist-na 12.2492 APE11-dist-na 10.493 APE10-dist-na 11.5214 APE9-dist-in 7.569 None PTR1007,PTR1008 PTR1007,PTR1008 XRAY 2.5 0.187 0.214 B 321.0 290.0 4 31 31 0 [[545, 807], [849, 1125]] 2.0 5cf6 Homo sapiens TYR_JAK2-2_HUMAN TYR 3.4e-87 298.0 1.0 260.0 260.0 993 994 995 997 999 882 898 902 973 975 974 976.0 1036 1024 1019 1018 1017 1016 1015 1014 1013 930 Tyrosine-protein kinase JAK2

PDB: 5CF6 — TYR JAK2_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name