PDB: 4ZIM — TYR JAK2_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 2 100.0% 4ZIMB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR JAK2-2 JAK2_HUMAN 4ZIMA O60674 842 1131 1132.0 4OK:61201 Type1 Inactive DFGin 6.2557 13.5245 ABAminus -102.09, -6.97 -147.71, 148.02 -137.31, 29.43 300.7, 95.51 -55.05, -34.04 in-in in 8.5947 Saltbr-in 2.797 HRD-in -53.87, -50.26 65.52, 9.71 in-in-in SNCiii in-in ActLoopNT-in 2.7319 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -90.04, 117.49 APE9-dihe-in -95.25, 146.52 APE8-dihe-in -75.87, 68.0 APE8-rot-na 26.85 APE67-dihe-in -81.7, -1.44 -56.38, -28.63 APE12-dist-na 13.0789 APE11-dist-na 12.4036 APE10-dist-na 12.9226 APE9-dist-in 7.5943 None PTR1007,PTR1008 PTR1007,PTR1008 XRAY 2.65 0.204 0.274 A 321.0 287.0 3 31 31 0 [[545, 807], [849, 1125]] 2.0 4zim TYR_JAK2-2_HUMAN TYR 3.4e-87 298.0 1.0 260.0 260.0 993 994 995 997 999 882 898 902 973 975 974 976.0 1036 1024 1019 1018 1017 1016 1015 1014 1013 930 Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 4ZIMB O60674 839 1132 1132.0 4OK:61201 Type1 Inactive DFGin 6.3104 13.573 ABAminus -101.81, -6.62 -147.61, 146.1 -135.69, 28.39 301.03, 95.65 -55.21, -33.63 in-in in 8.5735 Saltbr-in 2.8105 HRD-in -54.97, -54.79 72.19, 10.05 in-in-in SNCiii in-in ActLoopNT-in 2.7298 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -69.16, 96.7 APE9-dihe-in -86.92, 138.92 APE8-dihe-in -75.37, 68.14 APE8-rot-na 27.6 APE67-dihe-in -81.8, -0.82 -56.64, -28.71 APE12-dist-na 12.5642 APE11-dist-na 10.0973 APE10-dist-na 12.0461 APE9-dist-in 7.5773 None PTR1007,PTR1008 PTR1007,PTR1008 XRAY 2.65 0.204 0.274 B 321.0 294.0 0 31 31 0 [[545, 807], [849, 1125]] 2.0 4zim TYR_JAK2-2_HUMAN TYR 3.4e-87 298.0 1.0 260.0 260.0 993 994 995 997 999 882 898 902 973 975 974 976.0 1036 1024 1019 1018 1017 1016 1015 1014 1013 930 Tyrosine-protein kinase JAK2

PDB: 4ZIM — TYR JAK2_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 2 100.0% 4ZIMB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR JAK2-2 JAK2_HUMAN 4ZIMA O60674 842 1131 1132.0 4OK:61201 Type1 Inactive DFGin 6.2557 13.5245 ABAminus -102.09, -6.97 -147.71, 148.02 -137.31, 29.43 300.7, 95.51 -55.05, -34.04 in-in in 8.5947 Saltbr-in 2.797 HRD-in -53.87, -50.26 65.52, 9.71 in-in-in SNCiii in-in ActLoopNT-in 2.7319 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -90.04, 117.49 APE9-dihe-in -95.25, 146.52 APE8-dihe-in -75.87, 68.0 APE8-rot-na 26.85 APE67-dihe-in -81.7, -1.44 -56.38, -28.63 APE12-dist-na 13.0789 APE11-dist-na 12.4036 APE10-dist-na 12.9226 APE9-dist-in 7.5943 None PTR1007,PTR1008 PTR1007,PTR1008 XRAY 2.65 0.204 0.274 A 321.0 287.0 3 31 31 0 [[545, 807], [849, 1125]] 2.0 4zim Homo sapiens TYR_JAK2-2_HUMAN TYR 3.4e-87 298.0 1.0 260.0 260.0 993 994 995 997 999 882 898 902 973 975 974 976.0 1036 1024 1019 1018 1017 1016 1015 1014 1013 930 Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 4ZIMB O60674 839 1132 1132.0 4OK:61201 Type1 Inactive DFGin 6.3104 13.573 ABAminus -101.81, -6.62 -147.61, 146.1 -135.69, 28.39 301.03, 95.65 -55.21, -33.63 in-in in 8.5735 Saltbr-in 2.8105 HRD-in -54.97, -54.79 72.19, 10.05 in-in-in SNCiii in-in ActLoopNT-in 2.7298 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -69.16, 96.7 APE9-dihe-in -86.92, 138.92 APE8-dihe-in -75.37, 68.14 APE8-rot-na 27.6 APE67-dihe-in -81.8, -0.82 -56.64, -28.71 APE12-dist-na 12.5642 APE11-dist-na 10.0973 APE10-dist-na 12.0461 APE9-dist-in 7.5773 None PTR1007,PTR1008 PTR1007,PTR1008 XRAY 2.65 0.204 0.274 B 321.0 294.0 0 31 31 0 [[545, 807], [849, 1125]] 2.0 4zim Homo sapiens TYR_JAK2-2_HUMAN TYR 3.4e-87 298.0 1.0 260.0 260.0 993 994 995 997 999 882 898 902 973 975 974 976.0 1036 1024 1019 1018 1017 1016 1015 1014 1013 930 Tyrosine-protein kinase JAK2

PDB: 4ZIM — TYR JAK2_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name