PDB: 4YR8 — CMGC MK08_HUMAN

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 4 100.0% 4YR8A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC MAPK8 MK08_HUMAN 4YR8A P45983 8 362 427.0 No_ligand No_ligand Inactive DFGin 3.746 13.6511 ABAminus -92.48, -36.82 -128.7, -177.95 -116.24, 9.95 302.59, 109.3 79.22, -159.79 in-in in 9.397 Saltbr-in 2.7167 HRD-in -91.12, -57.47 70.8, -11.5 in-none-out SNCino none-out ActLoopNT-none 999.0 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 120.35 APE8-dihe-in -90.35, 105.5 APE8-rot-out 50.94 APE67-dihe-in -67.62, -16.88 -108.83, 0.82 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 12.1748 None None None XRAY 2.4 0.218 0.239 A 371.0 320.0 17 27 14 13 [[26, 321]] 1.0 4yr8 CMGC_MAPK8_HUMAN CMGC 8.5e-85 290.6 1.0 301.0 301.0 168 169 170 172 174 55 73 77 148 150 149 151.0 207 195 190 189 188 187 186 185 184 109 Mitogen-activated protein kinase 8
CMGC MAPK8 MK08_HUMAN 4YR8C P45983 10 362 427.0 No_ligand No_ligand Inactive DFGin 4.3451 13.3914 ABAminus -88.52, -41.45 -131.53, -175.1 -114.96, 11.59 302.69, 109.92 79.73, 999.0 in-in in 8.8736 Saltbr-in 2.6944 HRD-in -68.29, -62.18 77.05, -0.67 in-none-none SNCinn none-none ActLoopNT-none 999.0 ActLoopCT-none nonTYR APEdihe_aanni APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 118.23 APE8-rot-none 999.0 APE67-dihe-in -64.66, -18.42 -99.29, -2.8 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 None None None XRAY 2.4 0.218 0.239 C 371.0 318.0 21 27 11 16 [[26, 321]] 1.0 4yr8 CMGC_MAPK8_HUMAN CMGC 8.5e-85 290.6 1.0 301.0 301.0 168 169 170 172 174 55 73 77 148 150 149 151.0 207 195 190 189 188 187 186 185 184 109 Mitogen-activated protein kinase 8
CMGC MAPK8 MK08_HUMAN 4YR8E P45983 7 362 427.0 No_ligand No_ligand Inactive DFGin 3.7276 14.1372 ABAminus -86.08, -36.9 -129.28, 170.42 -104.47, 7.33 299.61, 110.26 81.64, -165.5 out-out out 10.093 Saltbr-out 3.6951 HRD-in -78.61, -55.83 65.3, 1.9 out-out-out SNCooo out-out ActLoopNT-out 6.8909 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, -50.39 APE8-dihe-in -79.39, 102.65 APE8-rot-out 53.21 APE67-dihe-in -61.82, -18.77 -109.31, -0.43 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 11.7944 None None None XRAY 2.4 0.218 0.239 E 371.0 317.0 17 27 15 12 [[26, 321]] 1.0 4yr8 CMGC_MAPK8_HUMAN CMGC 8.5e-85 290.6 1.0 301.0 301.0 168 169 170 172 174 55 73 77 148 150 149 151.0 207 195 190 189 188 187 186 185 184 109 Mitogen-activated protein kinase 8
CMGC MAPK8 MK08_HUMAN 4YR8F P45983 10 362 427.0 No_ligand No_ligand Inactive DFGin 4.6068 13.3341 ABAminus -92.28, -40.63 -125.1, 178.19 -117.35, 11.6 304.63, 110.41 81.03, 999.0 in-in in 8.5474 Saltbr-in 2.4139 HRD-in -61.32, -58.08 77.0, -3.6 in-none-none SNCinn none-none ActLoopNT-none 999.0 ActLoopCT-none nonTYR APEdihe_aanni APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 114.52 APE8-rot-none 999.0 APE67-dihe-in -64.79, -18.18 -101.48, -2.27 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 None None None XRAY 2.4 0.218 0.239 F 371.0 300.0 38 27 11 16 [[26, 321]] 1.0 4yr8 CMGC_MAPK8_HUMAN CMGC 8.5e-85 290.6 1.0 301.0 301.0 168 169 170 172 174 55 73 77 148 150 149 151.0 207 195 190 189 188 187 186 185 184 109 Mitogen-activated protein kinase 8

PDB: 4YR8 — CMGC MK08_HUMAN

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 4 100.0% 4YR8A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC MAPK8 MK08_HUMAN 4YR8A P45983 8 362 427.0 No_ligand No_ligand Inactive DFGin 3.746 13.6511 ABAminus -92.48, -36.82 -128.7, -177.95 -116.24, 9.95 302.59, 109.3 79.22, -159.79 in-in in 9.397 Saltbr-in 2.7167 HRD-in -91.12, -57.47 70.8, -11.5 in-none-out SNCino none-out ActLoopNT-none 999.0 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 120.35 APE8-dihe-in -90.35, 105.5 APE8-rot-out 50.94 APE67-dihe-in -67.62, -16.88 -108.83, 0.82 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 12.1748 None None None XRAY 2.4 0.218 0.239 A 371.0 320.0 17 27 14 13 [[26, 321]] 1.0 4yr8 Homo sapiens CMGC_MAPK8_HUMAN CMGC 8.5e-85 290.6 1.0 301.0 301.0 168 169 170 172 174 55 73 77 148 150 149 151.0 207 195 190 189 188 187 186 185 184 109 Mitogen-activated protein kinase 8
CMGC MAPK8 MK08_HUMAN 4YR8C P45983 10 362 427.0 No_ligand No_ligand Inactive DFGin 4.3451 13.3914 ABAminus -88.52, -41.45 -131.53, -175.1 -114.96, 11.59 302.69, 109.92 79.73, 999.0 in-in in 8.8736 Saltbr-in 2.6944 HRD-in -68.29, -62.18 77.05, -0.67 in-none-none SNCinn none-none ActLoopNT-none 999.0 ActLoopCT-none nonTYR APEdihe_aanni APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 118.23 APE8-rot-none 999.0 APE67-dihe-in -64.66, -18.42 -99.29, -2.8 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 None None None XRAY 2.4 0.218 0.239 C 371.0 318.0 21 27 11 16 [[26, 321]] 1.0 4yr8 Homo sapiens CMGC_MAPK8_HUMAN CMGC 8.5e-85 290.6 1.0 301.0 301.0 168 169 170 172 174 55 73 77 148 150 149 151.0 207 195 190 189 188 187 186 185 184 109 Mitogen-activated protein kinase 8
CMGC MAPK8 MK08_HUMAN 4YR8E P45983 7 362 427.0 No_ligand No_ligand Inactive DFGin 3.7276 14.1372 ABAminus -86.08, -36.9 -129.28, 170.42 -104.47, 7.33 299.61, 110.26 81.64, -165.5 out-out out 10.093 Saltbr-out 3.6951 HRD-in -78.61, -55.83 65.3, 1.9 out-out-out SNCooo out-out ActLoopNT-out 6.8909 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, -50.39 APE8-dihe-in -79.39, 102.65 APE8-rot-out 53.21 APE67-dihe-in -61.82, -18.77 -109.31, -0.43 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 11.7944 None None None XRAY 2.4 0.218 0.239 E 371.0 317.0 17 27 15 12 [[26, 321]] 1.0 4yr8 Homo sapiens CMGC_MAPK8_HUMAN CMGC 8.5e-85 290.6 1.0 301.0 301.0 168 169 170 172 174 55 73 77 148 150 149 151.0 207 195 190 189 188 187 186 185 184 109 Mitogen-activated protein kinase 8
CMGC MAPK8 MK08_HUMAN 4YR8F P45983 10 362 427.0 No_ligand No_ligand Inactive DFGin 4.6068 13.3341 ABAminus -92.28, -40.63 -125.1, 178.19 -117.35, 11.6 304.63, 110.41 81.03, 999.0 in-in in 8.5474 Saltbr-in 2.4139 HRD-in -61.32, -58.08 77.0, -3.6 in-none-none SNCinn none-none ActLoopNT-none 999.0 ActLoopCT-none nonTYR APEdihe_aanni APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 114.52 APE8-rot-none 999.0 APE67-dihe-in -64.79, -18.18 -101.48, -2.27 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 None None None XRAY 2.4 0.218 0.239 F 371.0 300.0 38 27 11 16 [[26, 321]] 1.0 4yr8 Homo sapiens CMGC_MAPK8_HUMAN CMGC 8.5e-85 290.6 1.0 301.0 301.0 168 169 170 172 174 55 73 77 148 150 149 151.0 207 195 190 189 188 187 186 185 184 109 Mitogen-activated protein kinase 8

PDB: 4YR8 — CMGC MK08_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name