PDB: 4Y85 — STE M3K8_HUMAN

Total number of chains: 3
Active chains: 3
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 3 100.0% 4Y85A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
STE MAP3K8 M3K8_HUMAN 4Y85A P41279 73 390 467.0 499:401 Type1 Active DFGin 6.4495 13.7074 BLAminus -125.84, 169.57 64.84, 98.71 -111.77, 16.68 296.07, 91.66 -61.47, -26.58 in-na in 7.5738 Saltbr-na 2.805 HRD-in -62.46, -46.04 78.32, -7.97 na-in-in SNCaii in-in ActLoopNT-in 3.0215 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -113.49, 144.17 APE9-dihe-na 115.1, 178.84 APE8-dihe-in -97.8, 118.96 APE8-rot-in 303.98 APE67-dihe-in -55.87, -36.44 -46.75, -46.09 APE12-dist-in 9.8023 APE11-dist-in 11.4362 APE10-dist-in 5.5899 APE9-dist-in 3.5846 None None None XRAY 2.33 0.179 0.207 A 332.0 307.0 3 28 28 0 [[136, 388]] 1.0 4y85 STE_MAP3K8_HUMAN STE 9.9e-75 257.3 7.0 256.0 250.0 269 270 271 273 275 167 178 182 250 252 251 253.0 309 297 292 291 290 289 288 287 286 208 Mitogen-activated protein kinase kinase kinase 8
STE MAP3K8 M3K8_HUMAN 4Y85B P41279 73 390 467.0 499:401 Type1 Active DFGin 6.5002 13.6617 BLAminus -125.73, 169.75 64.0, 98.82 -111.42, 16.46 295.94, 92.79 -60.36, -27.43 in-na in 7.4766 Saltbr-na 2.771 HRD-in -63.07, -45.87 78.49, -7.37 na-in-in SNCaii in-in ActLoopNT-in 3.0205 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -113.8, 144.13 APE9-dihe-na 114.25, 178.8 APE8-dihe-in -97.63, 117.87 APE8-rot-in 304.63 APE67-dihe-in -56.41, -36.16 -46.53, -45.15 APE12-dist-in 9.8074 APE11-dist-in 11.4211 APE10-dist-in 5.5794 APE9-dist-in 3.5914 None None None XRAY 2.33 0.179 0.207 B 332.0 306.0 3 28 28 0 [[136, 388]] 1.0 4y85 STE_MAP3K8_HUMAN STE 9.9e-75 257.3 7.0 256.0 250.0 269 270 271 273 275 167 178 182 250 252 251 253.0 309 297 292 291 290 289 288 287 286 208 Mitogen-activated protein kinase kinase kinase 8
STE MAP3K8 M3K8_HUMAN 4Y85C P41279 73 390 467.0 499:401 Type1 Active DFGin 6.4808 13.6837 BLAminus -126.2, 169.22 64.27, 99.76 -112.85, 16.66 296.43, 92.51 -60.53, -27.85 in-na in 7.595 Saltbr-na 2.7755 HRD-in -62.99, -45.6 77.82, -6.53 na-in-in SNCaii in-in ActLoopNT-in 3.0092 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -114.65, 144.47 APE9-dihe-na 114.68, 178.91 APE8-dihe-in -96.47, 118.22 APE8-rot-in 303.78 APE67-dihe-in -57.1, -35.93 -46.75, -44.73 APE12-dist-in 9.8117 APE11-dist-in 11.3483 APE10-dist-in 5.5321 APE9-dist-in 3.587 None None None XRAY 2.33 0.179 0.207 C 332.0 303.0 5 28 28 0 [[136, 388]] 1.0 4y85 STE_MAP3K8_HUMAN STE 9.9e-75 257.3 7.0 256.0 250.0 269 270 271 273 275 167 178 182 250 252 251 253.0 309 297 292 291 290 289 288 287 286 208 Mitogen-activated protein kinase kinase kinase 8

PDB: 4Y85 — STE M3K8_HUMAN

Total number of chains: 3
Active chains: 3
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 3 100.0% 4Y85A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
STE MAP3K8 M3K8_HUMAN 4Y85A P41279 73 390 467.0 499:401 Type1 Active DFGin 6.4495 13.7074 BLAminus -125.84, 169.57 64.84, 98.71 -111.77, 16.68 296.07, 91.66 -61.47, -26.58 in-na in 7.5738 Saltbr-na 2.805 HRD-in -62.46, -46.04 78.32, -7.97 na-in-in SNCaii in-in ActLoopNT-in 3.0215 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -113.49, 144.17 APE9-dihe-na 115.1, 178.84 APE8-dihe-in -97.8, 118.96 APE8-rot-in 303.98 APE67-dihe-in -55.87, -36.44 -46.75, -46.09 APE12-dist-in 9.8023 APE11-dist-in 11.4362 APE10-dist-in 5.5899 APE9-dist-in 3.5846 None None None XRAY 2.33 0.179 0.207 A 332.0 307.0 3 28 28 0 [[136, 388]] 1.0 4y85 Homo sapiens STE_MAP3K8_HUMAN STE 9.9e-75 257.3 7.0 256.0 250.0 269 270 271 273 275 167 178 182 250 252 251 253.0 309 297 292 291 290 289 288 287 286 208 Mitogen-activated protein kinase kinase kinase 8
STE MAP3K8 M3K8_HUMAN 4Y85B P41279 73 390 467.0 499:401 Type1 Active DFGin 6.5002 13.6617 BLAminus -125.73, 169.75 64.0, 98.82 -111.42, 16.46 295.94, 92.79 -60.36, -27.43 in-na in 7.4766 Saltbr-na 2.771 HRD-in -63.07, -45.87 78.49, -7.37 na-in-in SNCaii in-in ActLoopNT-in 3.0205 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -113.8, 144.13 APE9-dihe-na 114.25, 178.8 APE8-dihe-in -97.63, 117.87 APE8-rot-in 304.63 APE67-dihe-in -56.41, -36.16 -46.53, -45.15 APE12-dist-in 9.8074 APE11-dist-in 11.4211 APE10-dist-in 5.5794 APE9-dist-in 3.5914 None None None XRAY 2.33 0.179 0.207 B 332.0 306.0 3 28 28 0 [[136, 388]] 1.0 4y85 Homo sapiens STE_MAP3K8_HUMAN STE 9.9e-75 257.3 7.0 256.0 250.0 269 270 271 273 275 167 178 182 250 252 251 253.0 309 297 292 291 290 289 288 287 286 208 Mitogen-activated protein kinase kinase kinase 8
STE MAP3K8 M3K8_HUMAN 4Y85C P41279 73 390 467.0 499:401 Type1 Active DFGin 6.4808 13.6837 BLAminus -126.2, 169.22 64.27, 99.76 -112.85, 16.66 296.43, 92.51 -60.53, -27.85 in-na in 7.595 Saltbr-na 2.7755 HRD-in -62.99, -45.6 77.82, -6.53 na-in-in SNCaii in-in ActLoopNT-in 3.0092 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -114.65, 144.47 APE9-dihe-na 114.68, 178.91 APE8-dihe-in -96.47, 118.22 APE8-rot-in 303.78 APE67-dihe-in -57.1, -35.93 -46.75, -44.73 APE12-dist-in 9.8117 APE11-dist-in 11.3483 APE10-dist-in 5.5321 APE9-dist-in 3.587 None None None XRAY 2.33 0.179 0.207 C 332.0 303.0 5 28 28 0 [[136, 388]] 1.0 4y85 Homo sapiens STE_MAP3K8_HUMAN STE 9.9e-75 257.3 7.0 256.0 250.0 269 270 271 273 275 167 178 182 250 252 251 253.0 309 297 292 291 290 289 288 287 286 208 Mitogen-activated protein kinase kinase kinase 8

PDB: 4Y85 — STE M3K8_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name