PDB: 4Y83 — STE M3K8_HUMAN

Total number of chains: 3
Active chains: 1
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 3 100.0% 4Y83B
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
STE MAP3K8 M3K8_HUMAN 4Y83A P41279 73 389 467.0 49B:401 Type1 Active DFGin 6.0993 13.8195 BLAminus -124.59, 171.95 65.19, 92.7 -106.98, 18.83 296.59, 87.7 -55.3, -38.71 in-na in 7.9632 Saltbr-na 3.95 HRD-in -58.39, -44.97 76.28, -1.41 na-in-in SNCaii in-in ActLoopNT-in 2.9848 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -121.5, 134.53 APE9-dihe-na 124.17, -161.58 APE8-dihe-in -108.22, 120.72 APE8-rot-in 305.37 APE67-dihe-in -53.37, -39.86 -40.43, -53.79 APE12-dist-in 10.5733 APE11-dist-in 11.4347 APE10-dist-in 5.6628 APE9-dist-in 3.5955 None None None XRAY 2.89 0.204 0.239 A 332.0 299.0 7 28 28 0 [[136, 388]] 1.0 4y83 STE_MAP3K8_HUMAN STE 9.9e-75 257.3 7.0 256.0 250.0 269 270 271 273 275 167 178 182 250 252 251 253.0 309 297 292 291 290 289 288 287 286 208 Mitogen-activated protein kinase kinase kinase 8
STE MAP3K8 M3K8_HUMAN 4Y83B P41279 73 390 467.0 49B:401 Type1 Inactive DFGin 6.1087 13.8331 BLAminus -124.82, 178.39 58.04, 91.08 -107.1, 19.86 295.8, 87.89 -54.55, -39.25 in-na in 7.9545 Saltbr-na 3.9252 HRD-out -89.84, 93.56 -65.3, 5.72 na-in-in SNCaii in-in ActLoopNT-in 2.9028 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -120.81, 133.53 APE9-dihe-na 123.34, -162.02 APE8-dihe-in -108.51, 121.14 APE8-rot-in 304.25 APE67-dihe-in -53.46, -41.03 -40.77, -53.11 APE12-dist-in 10.4389 APE11-dist-in 11.3734 APE10-dist-in 5.6636 APE9-dist-in 3.6903 None None None XRAY 2.89 0.204 0.239 B 332.0 302.0 6 28 28 0 [[136, 388]] 1.0 4y83 STE_MAP3K8_HUMAN STE 9.9e-75 257.3 7.0 256.0 250.0 269 270 271 273 275 167 178 182 250 252 251 253.0 309 297 292 291 290 289 288 287 286 208 Mitogen-activated protein kinase kinase kinase 8
STE MAP3K8 M3K8_HUMAN 4Y83C P41279 74 389 467.0 49B:401 Type1 Inactive DFGin 5.5842 13.4418 BLAminus -110.1, 168.68 58.93, 91.32 -105.74, 14.12 293.23, 84.53 -55.17, -37.01 in-na in 7.9364 Saltbr-na 999.0 HRD-out -77.01, 90.27 -64.95, 5.59 na-in-in SNCaii in-in ActLoopNT-in 2.8475 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -119.68, 133.22 APE9-dihe-na 121.85, -162.73 APE8-dihe-in -109.52, 121.69 APE8-rot-in 305.8 APE67-dihe-in -52.55, -40.59 -40.63, -53.14 APE12-dist-in 10.4515 APE11-dist-in 11.3786 APE10-dist-in 5.6396 APE9-dist-in 3.6795 None None None XRAY 2.89 0.204 0.239 C 332.0 293.0 11 28 27 1 [[136, 388]] 1.0 4y83 STE_MAP3K8_HUMAN STE 9.9e-75 257.3 7.0 256.0 250.0 269 270 271 273 275 167 178 182 250 252 251 253.0 309 297 292 291 290 289 288 287 286 208 Mitogen-activated protein kinase kinase kinase 8

PDB: 4Y83 — STE M3K8_HUMAN

Total number of chains: 3
Active chains: 1
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 3 100.0% 4Y83B
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
STE MAP3K8 M3K8_HUMAN 4Y83A P41279 73 389 467.0 49B:401 Type1 Active DFGin 6.0993 13.8195 BLAminus -124.59, 171.95 65.19, 92.7 -106.98, 18.83 296.59, 87.7 -55.3, -38.71 in-na in 7.9632 Saltbr-na 3.95 HRD-in -58.39, -44.97 76.28, -1.41 na-in-in SNCaii in-in ActLoopNT-in 2.9848 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -121.5, 134.53 APE9-dihe-na 124.17, -161.58 APE8-dihe-in -108.22, 120.72 APE8-rot-in 305.37 APE67-dihe-in -53.37, -39.86 -40.43, -53.79 APE12-dist-in 10.5733 APE11-dist-in 11.4347 APE10-dist-in 5.6628 APE9-dist-in 3.5955 None None None XRAY 2.89 0.204 0.239 A 332.0 299.0 7 28 28 0 [[136, 388]] 1.0 4y83 Homo sapiens STE_MAP3K8_HUMAN STE 9.9e-75 257.3 7.0 256.0 250.0 269 270 271 273 275 167 178 182 250 252 251 253.0 309 297 292 291 290 289 288 287 286 208 Mitogen-activated protein kinase kinase kinase 8
STE MAP3K8 M3K8_HUMAN 4Y83B P41279 73 390 467.0 49B:401 Type1 Inactive DFGin 6.1087 13.8331 BLAminus -124.82, 178.39 58.04, 91.08 -107.1, 19.86 295.8, 87.89 -54.55, -39.25 in-na in 7.9545 Saltbr-na 3.9252 HRD-out -89.84, 93.56 -65.3, 5.72 na-in-in SNCaii in-in ActLoopNT-in 2.9028 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -120.81, 133.53 APE9-dihe-na 123.34, -162.02 APE8-dihe-in -108.51, 121.14 APE8-rot-in 304.25 APE67-dihe-in -53.46, -41.03 -40.77, -53.11 APE12-dist-in 10.4389 APE11-dist-in 11.3734 APE10-dist-in 5.6636 APE9-dist-in 3.6903 None None None XRAY 2.89 0.204 0.239 B 332.0 302.0 6 28 28 0 [[136, 388]] 1.0 4y83 Homo sapiens STE_MAP3K8_HUMAN STE 9.9e-75 257.3 7.0 256.0 250.0 269 270 271 273 275 167 178 182 250 252 251 253.0 309 297 292 291 290 289 288 287 286 208 Mitogen-activated protein kinase kinase kinase 8
STE MAP3K8 M3K8_HUMAN 4Y83C P41279 74 389 467.0 49B:401 Type1 Inactive DFGin 5.5842 13.4418 BLAminus -110.1, 168.68 58.93, 91.32 -105.74, 14.12 293.23, 84.53 -55.17, -37.01 in-na in 7.9364 Saltbr-na 999.0 HRD-out -77.01, 90.27 -64.95, 5.59 na-in-in SNCaii in-in ActLoopNT-in 2.8475 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -119.68, 133.22 APE9-dihe-na 121.85, -162.73 APE8-dihe-in -109.52, 121.69 APE8-rot-in 305.8 APE67-dihe-in -52.55, -40.59 -40.63, -53.14 APE12-dist-in 10.4515 APE11-dist-in 11.3786 APE10-dist-in 5.6396 APE9-dist-in 3.6795 None None None XRAY 2.89 0.204 0.239 C 332.0 293.0 11 28 27 1 [[136, 388]] 1.0 4y83 Homo sapiens STE_MAP3K8_HUMAN STE 9.9e-75 257.3 7.0 256.0 250.0 269 270 271 273 275 167 178 182 250 252 251 253.0 309 297 292 291 290 289 288 287 286 208 Mitogen-activated protein kinase kinase kinase 8

PDB: 4Y83 — STE M3K8_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name