| Group | Gene | SwissprotID | PDB | UniprotID | First_obs_res | Last_obs_res | Length_Unp | Ligand | Ligand_type | Activity_label | Spatial_label | Phe_Glu4_dis | Phe_Lys_dis | Dihedral_label | XDFG φ,ψ |
DFG-Asp φ,ψ |
DFG-Phe φ,ψ |
DFG-Phe χ1,χ2 |
DFG-Gly φ,ψ |
ChelixSaltbr_label | Chelix_label | Lys_Glu_dis | Saltbr_label | LysNZ_GluOE_dis | HRD_label | His φ,ψ | Arg φ,ψ | SNC_label | SNCpymol_label | ActLoop_label | ActLoopNT_label | DFG6_XHRD_dis | ActLoopCT_label | APEtype | APEdihe_label | APEdist_label | APE10_dihe_label | APE10 φ,ψ | APE9_dihe_label | APE9 φ,ψ | APE8_dihe_label | APE8 φ,ψ | APE8_rotamer_label | APE8 χ1 | APE67_label | APE6 φ,ψ | APE7 φ,ψ | APE12_dist_label | APE12_DFG4_dis | APE11_dist_label | APE11_DFG4_dis | APE10_dist_label | APE10_DFG4_dis | APE9_dist_label | APE9_Arg_dis | Chain_mut | Chain_phos | Modified_aa | Method | Resolution | Rvalue | FreeRvalue | Chain_id | ChainLen | Ordered_residues | DomainBreak | ActLoopLength | ActLoopResolvedResidues | ActLoopDisorderedResidues | Kinase_domains_Unp | N_Kinase_domains_Unp | pdb | Kincore_name | hmm | Evalue | Score | hmmbeg | hmmend | hmmlen | XDFGnum | DFGnum | PHEnum | DFG4num | DFG6num | LYSnum | GLUnum | GLU4num | XHRDnum | ARGnum | HRDnum | HRDaspnum | aFaspnum | APEnum | APE6num | APE7num | APE8num | APE9num | APE10num | APE11num | APE12num | Hinge1num | Protein_name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| TYR | FGFR1 | FGFR1_HUMAN | 4UWCA | P11362 | 465 | 765 | 822.0 | 4Y0:1773 | Type1 | Inactive | DFGin | 5.1849 | 13.2183 | BLAplus | -114.28, 167.51 | 64.08, 17.08 | -73.37, -20.76 | 56.56, 86.09 | -95.43, 0.2 | in-in | in | 7.6658 | Saltbr-in | 2.7686 | HRD-in | -68.21, -55.41 | 81.81, -19.33 | in-out-out | SNCioo | out-out | ActLoopNT-out | 8.0095 | ActLoopCT-out | TYR | APEdihe_iioai | APEdist_aaao | APE10-dihe-in | -96.15, 154.48 | APE9-dihe-in | -99.31, 111.29 | APE8-dihe-out | -53.23, -22.86 | APE8-rot-na | 338.31 | APE67-dihe-in | -68.82, -8.72 | -56.37, -24.16 | APE12-dist-na | 20.301 | APE11-dist-na | 21.1983 | APE10-dist-na | 19.3787 | APE9-dist-out | 11.7572 | C488A,C584S | None | None | XRAY | 1.96 | 0.179 | 0.206 | A | 309.0 | 301.0 | 0 | 30 | 30 | 0 | [[478, 756]] | 1.0 | 4uwc | TYR_FGFR1_HUMAN | TYR | 1.4e-104 | 354.9 | 1.0 | 260.0 | 260.0 | 640 | 641 | 642 | 644 | 646 | 514 | 531 | 535 | 620 | 622 | 621 | 623.0 | 682 | 670 | 665 | 664 | 663 | 662 | 661 | 660 | 659 | 562 | Fibroblast growth factor receptor 1 |
| TYR | FGFR1 | FGFR1_HUMAN | 4UWCB | P11362 | 459 | 764 | 822.0 | 4Y0:1770 | Type1 | Inactive | DFGin | 5.2203 | 13.0219 | BLAplus | -114.0, 163.28 | 67.1, 18.57 | -73.54, -21.45 | 56.42, 85.19 | -95.52, -0.76 | in-in | in | 7.5903 | Saltbr-in | 2.9197 | HRD-in | -68.93, -54.08 | 82.79, -14.74 | in-out-out | SNCioo | out-out | ActLoopNT-out | 8.3432 | ActLoopCT-out | TYR | APEdihe_iioai | APEdist_aaao | APE10-dihe-in | -101.38, 156.7 | APE9-dihe-in | -100.76, 111.03 | APE8-dihe-out | -54.68, -24.33 | APE8-rot-na | 334.31 | APE67-dihe-in | -64.61, -11.0 | -54.66, -28.32 | APE12-dist-na | 20.0881 | APE11-dist-na | 21.1466 | APE10-dist-na | 19.4809 | APE9-dist-out | 11.7331 | C488A,C584S | None | None | XRAY | 1.96 | 0.179 | 0.206 | B | 309.0 | 301.0 | 5 | 30 | 30 | 0 | [[478, 756]] | 1.0 | 4uwc | TYR_FGFR1_HUMAN | TYR | 1.4e-104 | 354.9 | 1.0 | 260.0 | 260.0 | 640 | 641 | 642 | 644 | 646 | 514 | 531 | 535 | 620 | 622 | 621 | 623.0 | 682 | 670 | 665 | 664 | 663 | 662 | 661 | 660 | 659 | 562 | Fibroblast growth factor receptor 1 |
| Group | Gene | SwissprotID | PDB | UniprotID | First_obs_res | Last_obs_res | Length_Unp | Ligand | Ligand_type | Activity_label | Spatial_label | Phe_Glu4_dis | Phe_Lys_dis | Dihedral_label | XDFG φ,ψ |
DFG-Asp φ,ψ |
DFG-Phe φ,ψ |
DFG-Phe χ1,χ2 |
DFG-Gly φ,ψ |
ChelixSaltbr_label | Chelix_label | Lys_Glu_dis | Saltbr_label | LysNZ_GluOE_dis | HRD_label | His φ,ψ | Arg φ,ψ | SNC_label | SNCpymol_label | ActLoop_label | ActLoopNT_label | DFG6_XHRD_dis | ActLoopCT_label | APEtype | APEdihe_label | APEdist_label | APE10_dihe_label | APE10 φ,ψ | APE9_dihe_label | APE9 φ,ψ | APE8_dihe_label | APE8 φ,ψ | APE8_rotamer_label | APE8 χ1 | APE67_label | APE6 φ,ψ | APE7 φ,ψ | APE12_dist_label | APE12_DFG4_dis | APE11_dist_label | APE11_DFG4_dis | APE10_dist_label | APE10_DFG4_dis | APE9_dist_label | APE9_Arg_dis | Chain_mut | Chain_phos | Modified_aa | Method | Resolution | Rvalue | FreeRvalue | Chain_id | ChainLen | Ordered_residues | DomainBreak | ActLoopLength | ActLoopResolvedResidues | ActLoopDisorderedResidues | Kinase_domains_Unp | N_Kinase_domains_Unp | pdb | Species | Kincore_name | hmm | Evalue | Score | hmmbeg | hmmend | hmmlen | XDFGnum | DFGnum | PHEnum | DFG4num | DFG6num | LYSnum | GLUnum | GLU4num | XHRDnum | ARGnum | HRDnum | HRDaspnum | aFaspnum | APEnum | APE6num | APE7num | APE8num | APE9num | APE10num | APE11num | APE12num | Hinge1num | Protein_name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| TYR | FGFR1 | FGFR1_HUMAN | 4UWCA | P11362 | 465 | 765 | 822.0 | 4Y0:1773 | Type1 | Inactive | DFGin | 5.1849 | 13.2183 | BLAplus | -114.28, 167.51 | 64.08, 17.08 | -73.37, -20.76 | 56.56, 86.09 | -95.43, 0.2 | in-in | in | 7.6658 | Saltbr-in | 2.7686 | HRD-in | -68.21, -55.41 | 81.81, -19.33 | in-out-out | SNCioo | out-out | ActLoopNT-out | 8.0095 | ActLoopCT-out | TYR | APEdihe_iioai | APEdist_aaao | APE10-dihe-in | -96.15, 154.48 | APE9-dihe-in | -99.31, 111.29 | APE8-dihe-out | -53.23, -22.86 | APE8-rot-na | 338.31 | APE67-dihe-in | -68.82, -8.72 | -56.37, -24.16 | APE12-dist-na | 20.301 | APE11-dist-na | 21.1983 | APE10-dist-na | 19.3787 | APE9-dist-out | 11.7572 | C488A,C584S | None | None | XRAY | 1.96 | 0.179 | 0.206 | A | 309.0 | 301.0 | 0 | 30 | 30 | 0 | [[478, 756]] | 1.0 | 4uwc | Homo sapiens | TYR_FGFR1_HUMAN | TYR | 1.4e-104 | 354.9 | 1.0 | 260.0 | 260.0 | 640 | 641 | 642 | 644 | 646 | 514 | 531 | 535 | 620 | 622 | 621 | 623.0 | 682 | 670 | 665 | 664 | 663 | 662 | 661 | 660 | 659 | 562 | Fibroblast growth factor receptor 1 |
| TYR | FGFR1 | FGFR1_HUMAN | 4UWCB | P11362 | 459 | 764 | 822.0 | 4Y0:1770 | Type1 | Inactive | DFGin | 5.2203 | 13.0219 | BLAplus | -114.0, 163.28 | 67.1, 18.57 | -73.54, -21.45 | 56.42, 85.19 | -95.52, -0.76 | in-in | in | 7.5903 | Saltbr-in | 2.9197 | HRD-in | -68.93, -54.08 | 82.79, -14.74 | in-out-out | SNCioo | out-out | ActLoopNT-out | 8.3432 | ActLoopCT-out | TYR | APEdihe_iioai | APEdist_aaao | APE10-dihe-in | -101.38, 156.7 | APE9-dihe-in | -100.76, 111.03 | APE8-dihe-out | -54.68, -24.33 | APE8-rot-na | 334.31 | APE67-dihe-in | -64.61, -11.0 | -54.66, -28.32 | APE12-dist-na | 20.0881 | APE11-dist-na | 21.1466 | APE10-dist-na | 19.4809 | APE9-dist-out | 11.7331 | C488A,C584S | None | None | XRAY | 1.96 | 0.179 | 0.206 | B | 309.0 | 301.0 | 5 | 30 | 30 | 0 | [[478, 756]] | 1.0 | 4uwc | Homo sapiens | TYR_FGFR1_HUMAN | TYR | 1.4e-104 | 354.9 | 1.0 | 260.0 | 260.0 | 640 | 641 | 642 | 644 | 646 | 514 | 531 | 535 | 620 | 622 | 621 | 623.0 | 682 | 670 | 665 | 664 | 663 | 662 | 661 | 660 | 659 | 562 | Fibroblast growth factor receptor 1 |
| Spatial label | Dihedral label | Number of Chains | Percent | Representative |
|---|
| Group | Gene | SwissprotID | PDB | UniprotID | First_obs_res | Last_obs_res | Length_Unp | Ligand | Ligand_type | Activity_label | Spatial_label | Phe_Glu4_dis | Phe_Lys_dis | Dihedral_label | XDFG φ,ψ |
DFG-Asp φ,ψ |
DFG-Phe φ,ψ |
DFG-Phe χ1,χ2 |
DFG-Gly φ,ψ |
ChelixSaltbr_label | Chelix_label | Lys_Glu_dis | Saltbr_label | LysNZ_GluOE_dis | HRD_label | His φ,ψ | Arg φ,ψ | SNC_label | SNCpymol_label | ActLoop_label | ActLoopNT_label | DFG6_XHRD_dis | ActLoopCT_label | APEtype | APEdihe_label | APEdist_label | APE10_dihe_label | APE10 φ,ψ | APE9_dihe_label | APE9 φ,ψ | APE8_dihe_label | APE8 φ,ψ | APE8_rotamer_label | APE8 χ1 | APE67_label | APE6 φ,ψ | APE7 φ,ψ | APE12_dist_label | APE12_DFG4_dis | APE11_dist_label | APE11_DFG4_dis | APE10_dist_label | APE10_DFG4_dis | APE9_dist_label | APE9_Arg_dis | Chain_mut | Chain_phos | Modified_aa | Method | Resolution | Rvalue | FreeRvalue | Chain_id | ChainLen | Ordered_residues | DomainBreak | ActLoopLength | ActLoopResolvedResidues | ActLoopDisorderedResidues | Kinase_domains_Unp | N_Kinase_domains_Unp | pdb | Species | Kincore_name | hmm | Evalue | Score | hmmbeg | hmmend | hmmlen | XDFGnum | DFGnum | PHEnum | DFG4num | DFG6num | LYSnum | GLUnum | GLU4num | XHRDnum | ARGnum | HRDnum | HRDaspnum | aFaspnum | APEnum | APE6num | APE7num | APE8num | APE9num | APE10num | APE11num | APE12num | Hinge1num | Protein_name |
|---|