PDB: 4NIF — 2 kinases

Total number of chains: 4
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 4 100.0% 4NIFA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CAMK RPS6KA1-2 KS6A1_HUMAN 4NIFA Q15418 413 728 735.0 No_ligand No_ligand Inactive DFGin 6.8677 14.6108 BLAminus -123.07, -176.37 48.87, 75.9 -90.5, 26.09 285.58, 73.35 -57.93, -22.0 in-in in 9.0989 Saltbr-in 2.6402 HRD-in -82.17, -49.47 73.17, -4.09 in-in-out SNCiio in-out ActLoopNT-in 2.9048 ActLoopCT-out nonTYR APEdihe_aannn APEdist_oooo APE10-dihe-na -76.32, -82.9 APE9-dihe-na -107.74, 999.0 APE8-dihe-none 999.0, 999.0 APE8-rot-none 999.0 APE67-dihe-none 999.0, 999.0 999.0, 999.0 APE12-dist-out 18.7396 APE11-dist-out 18.0535 APE10-dist-out 22.3995 APE9-dist-out 24.655 None None None XRAY 2.15 0.161 0.208 A 333.0 313.0 3 28 25 3 [[62, 321], [418, 675]] 2.0 4nif CAMK_RPS6KA1-2_HUMAN CAMK 1.3e-87 299.4 1.0 256.0 256.0 556 557 558 560 562 447 459 463 532 534 533 535.0 596 584 579 578 577 576 575 574 573 490 Ribosomal protein S6 kinase alpha-1
CAMK RPS6KA1-2 KS6A1_HUMAN 4NIFD Q15418 413 728 735.0 No_ligand No_ligand Inactive DFGin 6.8211 14.5091 BLAminus -125.54, -177.7 51.84, 74.57 -89.95, 24.53 284.87, 75.41 -55.2, -23.55 in-in in 9.0093 Saltbr-in 2.7014 HRD-in -81.48, -48.04 74.24, -5.51 in-in-out SNCiio in-out ActLoopNT-in 2.9634 ActLoopCT-out nonTYR APEdihe_aannn APEdist_ooon APE10-dihe-na -107.68, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 999.0 APE8-rot-none 999.0 APE67-dihe-none 999.0, -123.59 999.0, 999.0 APE12-dist-out 18.9604 APE11-dist-out 17.9149 APE10-dist-out 22.5878 APE9-dist-none 999.0 None None None XRAY 2.15 0.161 0.208 D 333.0 313.0 3 28 25 3 [[62, 321], [418, 675]] 2.0 4nif CAMK_RPS6KA1-2_HUMAN CAMK 1.3e-87 299.4 1.0 256.0 256.0 556 557 558 560 562 447 459 463 532 534 533 535.0 596 584 579 578 577 576 575 574 573 490 Ribosomal protein S6 kinase alpha-1
CMGC MAPK1 MK01_HUMAN 4NIFB P28482 9 360 360.0 ANP:401 ATPlike Inactive DFGin 6.7638 15.4088 BLAminus -131.87, -169.42 69.51, 63.01 -98.39, 22.71 281.57, 68.87 -63.28, -26.61 in-in in 9.0075 Saltbr-in 2.7834 HRD-in -68.77, -49.09 76.18, -3.84 in-in-out SNCiio in-out ActLoopNT-in 2.7275 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iioo APE10-dihe-na -127.8, 161.08 APE9-dihe-na -75.51, -26.3 APE8-dihe-in -152.23, 138.84 APE8-rot-out 180.18 APE67-dihe-in -71.26, -8.82 -111.88, 5.33 APE12-dist-in 8.1996 APE11-dist-in 11.9615 APE10-dist-out 8.903 APE9-dist-out 11.5131 None None None XRAY 2.15 0.161 0.208 B 362.0 349.0 3 31 28 3 [[25, 313]] 1.0 4nif CMGC_MAPK1_HUMAN CMGC 9.3e-86 293.7 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
CMGC MAPK1 MK01_HUMAN 4NIFE P28482 10 360 360.0 ANP:401 ATPlike Inactive DFGin 6.7991 15.6006 BLAminus -132.52, -168.43 65.68, 64.41 -97.79, 21.09 277.61, 67.0 -63.55, -23.2 in-in in 9.1704 Saltbr-in 2.7133 HRD-in -70.38, -48.01 73.58, -2.52 in-in-out SNCiio in-out ActLoopNT-in 2.7288 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iioo APE10-dihe-na -128.04, 157.14 APE9-dihe-na -71.47, -27.38 APE8-dihe-in -153.58, 137.78 APE8-rot-out 179.37 APE67-dihe-in -68.22, -5.95 -110.7, 4.02 APE12-dist-in 8.1436 APE11-dist-in 11.9289 APE10-dist-out 8.9408 APE9-dist-out 11.5278 None None None XRAY 2.15 0.161 0.208 E 362.0 348.0 3 31 28 3 [[25, 313]] 1.0 4nif CMGC_MAPK1_HUMAN CMGC 9.3e-86 293.7 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1

PDB: 4NIF — 2 kinases

Total number of chains: 4
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 4 100.0% 4NIFA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CAMK RPS6KA1-2 KS6A1_HUMAN 4NIFA Q15418 413 728 735.0 No_ligand No_ligand Inactive DFGin 6.8677 14.6108 BLAminus -123.07, -176.37 48.87, 75.9 -90.5, 26.09 285.58, 73.35 -57.93, -22.0 in-in in 9.0989 Saltbr-in 2.6402 HRD-in -82.17, -49.47 73.17, -4.09 in-in-out SNCiio in-out ActLoopNT-in 2.9048 ActLoopCT-out nonTYR APEdihe_aannn APEdist_oooo APE10-dihe-na -76.32, -82.9 APE9-dihe-na -107.74, 999.0 APE8-dihe-none 999.0, 999.0 APE8-rot-none 999.0 APE67-dihe-none 999.0, 999.0 999.0, 999.0 APE12-dist-out 18.7396 APE11-dist-out 18.0535 APE10-dist-out 22.3995 APE9-dist-out 24.655 None None None XRAY 2.15 0.161 0.208 A 333.0 313.0 3 28 25 3 [[62, 321], [418, 675]] 2.0 4nif Homo sapiens CAMK_RPS6KA1-2_HUMAN CAMK 1.3e-87 299.4 1.0 256.0 256.0 556 557 558 560 562 447 459 463 532 534 533 535.0 596 584 579 578 577 576 575 574 573 490 Ribosomal protein S6 kinase alpha-1
CAMK RPS6KA1-2 KS6A1_HUMAN 4NIFD Q15418 413 728 735.0 No_ligand No_ligand Inactive DFGin 6.8211 14.5091 BLAminus -125.54, -177.7 51.84, 74.57 -89.95, 24.53 284.87, 75.41 -55.2, -23.55 in-in in 9.0093 Saltbr-in 2.7014 HRD-in -81.48, -48.04 74.24, -5.51 in-in-out SNCiio in-out ActLoopNT-in 2.9634 ActLoopCT-out nonTYR APEdihe_aannn APEdist_ooon APE10-dihe-na -107.68, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 999.0 APE8-rot-none 999.0 APE67-dihe-none 999.0, -123.59 999.0, 999.0 APE12-dist-out 18.9604 APE11-dist-out 17.9149 APE10-dist-out 22.5878 APE9-dist-none 999.0 None None None XRAY 2.15 0.161 0.208 D 333.0 313.0 3 28 25 3 [[62, 321], [418, 675]] 2.0 4nif Homo sapiens CAMK_RPS6KA1-2_HUMAN CAMK 1.3e-87 299.4 1.0 256.0 256.0 556 557 558 560 562 447 459 463 532 534 533 535.0 596 584 579 578 577 576 575 574 573 490 Ribosomal protein S6 kinase alpha-1
CMGC MAPK1 MK01_HUMAN 4NIFB P28482 9 360 360.0 ANP:401 ATPlike Inactive DFGin 6.7638 15.4088 BLAminus -131.87, -169.42 69.51, 63.01 -98.39, 22.71 281.57, 68.87 -63.28, -26.61 in-in in 9.0075 Saltbr-in 2.7834 HRD-in -68.77, -49.09 76.18, -3.84 in-in-out SNCiio in-out ActLoopNT-in 2.7275 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iioo APE10-dihe-na -127.8, 161.08 APE9-dihe-na -75.51, -26.3 APE8-dihe-in -152.23, 138.84 APE8-rot-out 180.18 APE67-dihe-in -71.26, -8.82 -111.88, 5.33 APE12-dist-in 8.1996 APE11-dist-in 11.9615 APE10-dist-out 8.903 APE9-dist-out 11.5131 None None None XRAY 2.15 0.161 0.208 B 362.0 349.0 3 31 28 3 [[25, 313]] 1.0 4nif Homo sapiens CMGC_MAPK1_HUMAN CMGC 9.3e-86 293.7 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
CMGC MAPK1 MK01_HUMAN 4NIFE P28482 10 360 360.0 ANP:401 ATPlike Inactive DFGin 6.7991 15.6006 BLAminus -132.52, -168.43 65.68, 64.41 -97.79, 21.09 277.61, 67.0 -63.55, -23.2 in-in in 9.1704 Saltbr-in 2.7133 HRD-in -70.38, -48.01 73.58, -2.52 in-in-out SNCiio in-out ActLoopNT-in 2.7288 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iioo APE10-dihe-na -128.04, 157.14 APE9-dihe-na -71.47, -27.38 APE8-dihe-in -153.58, 137.78 APE8-rot-out 179.37 APE67-dihe-in -68.22, -5.95 -110.7, 4.02 APE12-dist-in 8.1436 APE11-dist-in 11.9289 APE10-dist-out 8.9408 APE9-dist-out 11.5278 None None None XRAY 2.15 0.161 0.208 E 362.0 348.0 3 31 28 3 [[25, 313]] 1.0 4nif Homo sapiens CMGC_MAPK1_HUMAN CMGC 9.3e-86 293.7 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1

PDB: 4NIF — 2 kinases

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name