PDB: 4K77 — TYR JAK1_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 2 100.0% 4K77A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR JAK1-2 JAK1_HUMAN 4K77A P23458 864 1154 1154.0 1Q4:1201 Type1 Inactive DFGin 6.2559 13.4641 ABAminus -120.21, 6.98 -152.33, 140.1 -135.8, 29.32 300.23, 84.02 -66.83, -17.3 in-in in 8.0423 Saltbr-in 2.62 HRD-in -83.59, -46.77 75.55, -1.36 in-in-out SNCiio in-out ActLoopNT-in 2.8065 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -110.78, 30.95 APE9-dihe-in -65.86, 137.27 APE8-dihe-in -79.1, 74.56 APE8-rot-na 31.39 APE67-dihe-in -73.63, -7.17 -57.69, -30.82 APE12-dist-na 11.1803 APE11-dist-na 12.7953 APE10-dist-na 9.921 APE9-dist-in 6.7505 None PTR1034,PTR1035 PTR1034,PTR1035 XRAY 2.4 0.193 0.251 A 302.0 284.0 7 31 31 0 [[583, 847], [875, 1151]] 2.0 4k77 TYR_JAK1-2_HUMAN TYR 2.2e-87 298.6 2.0 259.0 258.0 1020 1021 1022 1024 1026 908 925 929 1000 1002 1001 1003.0 1063 1051 1046 1045 1044 1043 1042 1041 1040 957 Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 4K77B P23458 865 1154 1154.0 1Q4:1201 Type1 Inactive DFGin 6.2823 13.5037 ABAminus -120.68, 0.99 -147.42, 142.05 -133.88, 36.74 297.84, 83.5 -67.02, -18.72 in-in in 7.9484 Saltbr-in 2.9218 HRD-in -85.03, -50.83 74.8, -3.74 in-in-out SNCiio in-out ActLoopNT-in 2.726 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -112.68, 47.05 APE9-dihe-in -77.0, 143.68 APE8-dihe-in -79.91, 78.18 APE8-rot-na 30.27 APE67-dihe-in -77.76, -4.87 -65.15, -27.78 APE12-dist-na 11.1372 APE11-dist-na 12.7263 APE10-dist-na 10.167 APE9-dist-in 6.81 None PTR1034,PTR1035 PTR1034,PTR1035 XRAY 2.4 0.193 0.251 B 302.0 282.0 8 31 31 0 [[583, 847], [875, 1151]] 2.0 4k77 TYR_JAK1-2_HUMAN TYR 2.2e-87 298.6 2.0 259.0 258.0 1020 1021 1022 1024 1026 908 925 929 1000 1002 1001 1003.0 1063 1051 1046 1045 1044 1043 1042 1041 1040 957 Tyrosine-protein kinase JAK1

PDB: 4K77 — TYR JAK1_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 2 100.0% 4K77A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR JAK1-2 JAK1_HUMAN 4K77A P23458 864 1154 1154.0 1Q4:1201 Type1 Inactive DFGin 6.2559 13.4641 ABAminus -120.21, 6.98 -152.33, 140.1 -135.8, 29.32 300.23, 84.02 -66.83, -17.3 in-in in 8.0423 Saltbr-in 2.62 HRD-in -83.59, -46.77 75.55, -1.36 in-in-out SNCiio in-out ActLoopNT-in 2.8065 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -110.78, 30.95 APE9-dihe-in -65.86, 137.27 APE8-dihe-in -79.1, 74.56 APE8-rot-na 31.39 APE67-dihe-in -73.63, -7.17 -57.69, -30.82 APE12-dist-na 11.1803 APE11-dist-na 12.7953 APE10-dist-na 9.921 APE9-dist-in 6.7505 None PTR1034,PTR1035 PTR1034,PTR1035 XRAY 2.4 0.193 0.251 A 302.0 284.0 7 31 31 0 [[583, 847], [875, 1151]] 2.0 4k77 Homo sapiens TYR_JAK1-2_HUMAN TYR 2.2e-87 298.6 2.0 259.0 258.0 1020 1021 1022 1024 1026 908 925 929 1000 1002 1001 1003.0 1063 1051 1046 1045 1044 1043 1042 1041 1040 957 Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 4K77B P23458 865 1154 1154.0 1Q4:1201 Type1 Inactive DFGin 6.2823 13.5037 ABAminus -120.68, 0.99 -147.42, 142.05 -133.88, 36.74 297.84, 83.5 -67.02, -18.72 in-in in 7.9484 Saltbr-in 2.9218 HRD-in -85.03, -50.83 74.8, -3.74 in-in-out SNCiio in-out ActLoopNT-in 2.726 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -112.68, 47.05 APE9-dihe-in -77.0, 143.68 APE8-dihe-in -79.91, 78.18 APE8-rot-na 30.27 APE67-dihe-in -77.76, -4.87 -65.15, -27.78 APE12-dist-na 11.1372 APE11-dist-na 12.7263 APE10-dist-na 10.167 APE9-dist-in 6.81 None PTR1034,PTR1035 PTR1034,PTR1035 XRAY 2.4 0.193 0.251 B 302.0 282.0 8 31 31 0 [[583, 847], [875, 1151]] 2.0 4k77 Homo sapiens TYR_JAK1-2_HUMAN TYR 2.2e-87 298.6 2.0 259.0 258.0 1020 1021 1022 1024 1026 908 925 929 1000 1002 1001 1003.0 1063 1051 1046 1045 1044 1043 1042 1041 1040 957 Tyrosine-protein kinase JAK1

PDB: 4K77 — TYR JAK1_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name