PDB: 4JI9 — TYR JAK2_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 2 100.0% 4JI9A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR JAK2-2 JAK2_HUMAN 4JI9A O60674 843 1132 1132.0 1M3:1201 Type1 Inactive DFGin 6.3239 13.4839 ABAminus -109.55, -7.44 -150.82, 140.52 -127.26, 30.44 299.13, 87.76 -52.84, -40.14 in-in in 8.585 Saltbr-in 2.6472 HRD-in -80.17, -42.61 76.43, -32.58 in-in-out SNCiio in-out ActLoopNT-in 2.7518 ActLoopCT-out TYR APEdihe_iiiai APEdist_aaao APE10-dihe-in -82.23, 111.22 APE9-dihe-in -100.97, 137.91 APE8-dihe-in -72.06, 68.6 APE8-rot-na 27.55 APE67-dihe-in -77.94, 0.46 -63.88, -26.22 APE12-dist-na 13.4406 APE11-dist-na 13.3171 APE10-dist-na 13.3201 APE9-dist-out 8.7568 None PTR1007,PTR1008 PTR1007,PTR1008 XRAY 2.4 0.203 0.245 A 300.0 286.0 4 31 31 0 [[545, 807], [849, 1125]] 2.0 4ji9 TYR_JAK2-2_HUMAN TYR 2.6e-87 298.4 1.0 260.0 260.0 993 994 995 997 999 882 898 902 973 975 974 976.0 1036 1024 1019 1018 1017 1016 1015 1014 1013 930 Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 4JI9B O60674 839 1132 1132.0 1M3:1201 Type1 Inactive DFGin 6.466 13.8486 ABAminus -116.52, -6.78 -147.24, 138.79 -124.56, 33.92 292.32, 86.1 -62.37, -34.07 in-in in 8.4907 Saltbr-in 2.8224 HRD-in -81.25, -47.33 75.7, -23.37 in-in-in SNCiii in-in ActLoopNT-in 2.6971 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -81.22, 150.08 APE9-dihe-in -122.92, 128.48 APE8-dihe-in -79.58, 77.7 APE8-rot-na 25.7 APE67-dihe-in -82.32, 3.2 -61.18, -27.11 APE12-dist-na 8.057 APE11-dist-na 10.4553 APE10-dist-na 11.075 APE9-dist-in 7.6984 None PTR1007,PTR1008 PTR1007,PTR1008 XRAY 2.4 0.203 0.245 B 300.0 290.0 4 31 31 0 [[545, 807], [849, 1125]] 2.0 4ji9 TYR_JAK2-2_HUMAN TYR 2.6e-87 298.4 1.0 260.0 260.0 993 994 995 997 999 882 898 902 973 975 974 976.0 1036 1024 1019 1018 1017 1016 1015 1014 1013 930 Tyrosine-protein kinase JAK2

PDB: 4JI9 — TYR JAK2_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 2 100.0% 4JI9A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR JAK2-2 JAK2_HUMAN 4JI9A O60674 843 1132 1132.0 1M3:1201 Type1 Inactive DFGin 6.3239 13.4839 ABAminus -109.55, -7.44 -150.82, 140.52 -127.26, 30.44 299.13, 87.76 -52.84, -40.14 in-in in 8.585 Saltbr-in 2.6472 HRD-in -80.17, -42.61 76.43, -32.58 in-in-out SNCiio in-out ActLoopNT-in 2.7518 ActLoopCT-out TYR APEdihe_iiiai APEdist_aaao APE10-dihe-in -82.23, 111.22 APE9-dihe-in -100.97, 137.91 APE8-dihe-in -72.06, 68.6 APE8-rot-na 27.55 APE67-dihe-in -77.94, 0.46 -63.88, -26.22 APE12-dist-na 13.4406 APE11-dist-na 13.3171 APE10-dist-na 13.3201 APE9-dist-out 8.7568 None PTR1007,PTR1008 PTR1007,PTR1008 XRAY 2.4 0.203 0.245 A 300.0 286.0 4 31 31 0 [[545, 807], [849, 1125]] 2.0 4ji9 Homo sapiens TYR_JAK2-2_HUMAN TYR 2.6e-87 298.4 1.0 260.0 260.0 993 994 995 997 999 882 898 902 973 975 974 976.0 1036 1024 1019 1018 1017 1016 1015 1014 1013 930 Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 4JI9B O60674 839 1132 1132.0 1M3:1201 Type1 Inactive DFGin 6.466 13.8486 ABAminus -116.52, -6.78 -147.24, 138.79 -124.56, 33.92 292.32, 86.1 -62.37, -34.07 in-in in 8.4907 Saltbr-in 2.8224 HRD-in -81.25, -47.33 75.7, -23.37 in-in-in SNCiii in-in ActLoopNT-in 2.6971 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -81.22, 150.08 APE9-dihe-in -122.92, 128.48 APE8-dihe-in -79.58, 77.7 APE8-rot-na 25.7 APE67-dihe-in -82.32, 3.2 -61.18, -27.11 APE12-dist-na 8.057 APE11-dist-na 10.4553 APE10-dist-na 11.075 APE9-dist-in 7.6984 None PTR1007,PTR1008 PTR1007,PTR1008 XRAY 2.4 0.203 0.245 B 300.0 290.0 4 31 31 0 [[545, 807], [849, 1125]] 2.0 4ji9 Homo sapiens TYR_JAK2-2_HUMAN TYR 2.6e-87 298.4 1.0 260.0 260.0 993 994 995 997 999 882 898 902 973 975 974 976.0 1036 1024 1019 1018 1017 1016 1015 1014 1013 930 Tyrosine-protein kinase JAK2

PDB: 4JI9 — TYR JAK2_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name