PDB: 4IZA — CMGC MK01_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 4IZAA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC MAPK1 MK01_HUMAN 4IZAA P28482 11 358 360.0 No_ligand No_ligand Inactive DFGin 6.7716 16.4482 BLAminus -129.85, -176.34 68.35, 73.87 -101.91, 18.02 280.1, 70.06 -62.61, -26.2 in-in in 9.9823 Saltbr-in 2.5085 HRD-in -67.1, -53.14 77.26, -1.94 in-in-out SNCiio in-out ActLoopNT-in 2.8209 ActLoopCT-out nonTYR APEdihe_aaoii APEdist_iooo APE10-dihe-na -129.09, 28.01 APE9-dihe-na -88.83, 7.82 APE8-dihe-out -120.34, 16.45 APE8-rot-in 313.77 APE67-dihe-in -71.68, -14.26 -48.45, -41.92 APE12-dist-in 11.2457 APE11-dist-out 7.4141 APE10-dist-out 12.8508 APE9-dist-out 9.9508 None TPO185,PTR187 TPO185,PTR187 XRAY 1.93 0.199 0.243 A 356.0 348.0 0 31 31 0 [[25, 313]] 1.0 4iza CMGC_MAPK1_HUMAN CMGC 8.8e-86 293.8 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
CMGC MAPK1 MK01_HUMAN 4IZAC P28482 11 358 360.0 No_ligand No_ligand Inactive DFGin 6.8504 16.4972 BLAminus -135.43, -175.74 69.86, 75.04 -101.18, 17.42 285.53, 76.16 -59.4, -25.37 out-none out 10.3448 Saltbr-none 999.0 HRD-in -67.56, -54.71 80.03, -9.06 none-in-out SNCnio in-out ActLoopNT-in 2.6429 ActLoopCT-out nonTYR APEdihe_aanoi APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 126.48 APE8-rot-out 60.76 APE67-dihe-in -68.72, -16.52 -103.69, -14.86 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 None TPO185,PTR187 TPO185,PTR187 XRAY 1.93 0.199 0.243 C 356.0 335.0 13 31 18 13 [[25, 313]] 1.0 4iza CMGC_MAPK1_HUMAN CMGC 8.8e-86 293.8 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1

PDB: 4IZA — CMGC MK01_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 4IZAA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC MAPK1 MK01_HUMAN 4IZAA P28482 11 358 360.0 No_ligand No_ligand Inactive DFGin 6.7716 16.4482 BLAminus -129.85, -176.34 68.35, 73.87 -101.91, 18.02 280.1, 70.06 -62.61, -26.2 in-in in 9.9823 Saltbr-in 2.5085 HRD-in -67.1, -53.14 77.26, -1.94 in-in-out SNCiio in-out ActLoopNT-in 2.8209 ActLoopCT-out nonTYR APEdihe_aaoii APEdist_iooo APE10-dihe-na -129.09, 28.01 APE9-dihe-na -88.83, 7.82 APE8-dihe-out -120.34, 16.45 APE8-rot-in 313.77 APE67-dihe-in -71.68, -14.26 -48.45, -41.92 APE12-dist-in 11.2457 APE11-dist-out 7.4141 APE10-dist-out 12.8508 APE9-dist-out 9.9508 None TPO185,PTR187 TPO185,PTR187 XRAY 1.93 0.199 0.243 A 356.0 348.0 0 31 31 0 [[25, 313]] 1.0 4iza Homo sapiens CMGC_MAPK1_HUMAN CMGC 8.8e-86 293.8 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1
CMGC MAPK1 MK01_HUMAN 4IZAC P28482 11 358 360.0 No_ligand No_ligand Inactive DFGin 6.8504 16.4972 BLAminus -135.43, -175.74 69.86, 75.04 -101.18, 17.42 285.53, 76.16 -59.4, -25.37 out-none out 10.3448 Saltbr-none 999.0 HRD-in -67.56, -54.71 80.03, -9.06 none-in-out SNCnio in-out ActLoopNT-in 2.6429 ActLoopCT-out nonTYR APEdihe_aanoi APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 126.48 APE8-rot-out 60.76 APE67-dihe-in -68.72, -16.52 -103.69, -14.86 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 None TPO185,PTR187 TPO185,PTR187 XRAY 1.93 0.199 0.243 C 356.0 335.0 13 31 18 13 [[25, 313]] 1.0 4iza Homo sapiens CMGC_MAPK1_HUMAN CMGC 8.8e-86 293.8 1.0 301.0 301.0 166 167 168 170 172 54 71 75 146 148 147 149.0 210 197 192 191 190 189 188 187 186 106 Mitogen-activated protein kinase 1

PDB: 4IZA — CMGC MK01_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name