PDB: 4IVD — TYR JAK1_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 2 100.0% 4IVDB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR JAK1-2 JAK1_HUMAN 4IVDA P23458 854 1154 1154.0 15T:61201 Type1 Inactive DFGin 6.3094 13.3038 ABAminus -118.43, 8.35 -154.11, 148.17 -137.65, 24.48 298.46, 83.68 -55.12, -27.34 in-in in 7.7486 Saltbr-in 2.7286 HRD-in -85.26, -46.42 71.64, 5.83 in-in-out SNCiio in-out ActLoopNT-in 2.9031 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -118.71, 33.92 APE9-dihe-in -63.4, 140.18 APE8-dihe-in -80.26, 75.71 APE8-rot-na 32.55 APE67-dihe-in -74.69, -4.74 -58.39, -31.37 APE12-dist-na 11.2468 APE11-dist-na 12.9702 APE10-dist-na 10.2675 APE9-dist-in 6.6549 None PTR1034,PTR1035 PTR1034,PTR1035 XRAY 1.93 0.204 0.247 A 302.0 291.0 10 31 31 0 [[583, 847], [875, 1151]] 2.0 4ivd TYR_JAK1-2_HUMAN TYR 2.2e-87 298.6 2.0 259.0 258.0 1020 1021 1022 1024 1026 908 925 929 1000 1002 1001 1003.0 1063 1051 1046 1045 1044 1043 1042 1041 1040 957 Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 4IVDB P23458 865 1154 1154.0 15T:61201 Type1 Inactive DFGin 6.4106 13.3698 ABAminus -112.55, 2.72 -159.22, 144.81 -135.21, 28.45 296.48, 84.97 -57.15, -29.77 in-in in 7.6756 Saltbr-in 2.7452 HRD-in -84.66, -44.43 68.53, 7.81 in-in-out SNCiio in-out ActLoopNT-in 2.9218 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -119.94, 35.04 APE9-dihe-in -66.46, 139.38 APE8-dihe-in -79.29, 77.36 APE8-rot-na 30.63 APE67-dihe-in -76.81, -5.82 -62.53, -27.62 APE12-dist-na 11.2208 APE11-dist-na 12.9738 APE10-dist-na 10.2444 APE9-dist-in 6.6658 None PTR1034,PTR1035 PTR1034,PTR1035 XRAY 1.93 0.204 0.247 B 302.0 282.0 8 31 31 0 [[583, 847], [875, 1151]] 2.0 4ivd TYR_JAK1-2_HUMAN TYR 2.2e-87 298.6 2.0 259.0 258.0 1020 1021 1022 1024 1026 908 925 929 1000 1002 1001 1003.0 1063 1051 1046 1045 1044 1043 1042 1041 1040 957 Tyrosine-protein kinase JAK1

PDB: 4IVD — TYR JAK1_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 2 100.0% 4IVDB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR JAK1-2 JAK1_HUMAN 4IVDA P23458 854 1154 1154.0 15T:61201 Type1 Inactive DFGin 6.3094 13.3038 ABAminus -118.43, 8.35 -154.11, 148.17 -137.65, 24.48 298.46, 83.68 -55.12, -27.34 in-in in 7.7486 Saltbr-in 2.7286 HRD-in -85.26, -46.42 71.64, 5.83 in-in-out SNCiio in-out ActLoopNT-in 2.9031 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -118.71, 33.92 APE9-dihe-in -63.4, 140.18 APE8-dihe-in -80.26, 75.71 APE8-rot-na 32.55 APE67-dihe-in -74.69, -4.74 -58.39, -31.37 APE12-dist-na 11.2468 APE11-dist-na 12.9702 APE10-dist-na 10.2675 APE9-dist-in 6.6549 None PTR1034,PTR1035 PTR1034,PTR1035 XRAY 1.93 0.204 0.247 A 302.0 291.0 10 31 31 0 [[583, 847], [875, 1151]] 2.0 4ivd Homo sapiens TYR_JAK1-2_HUMAN TYR 2.2e-87 298.6 2.0 259.0 258.0 1020 1021 1022 1024 1026 908 925 929 1000 1002 1001 1003.0 1063 1051 1046 1045 1044 1043 1042 1041 1040 957 Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 4IVDB P23458 865 1154 1154.0 15T:61201 Type1 Inactive DFGin 6.4106 13.3698 ABAminus -112.55, 2.72 -159.22, 144.81 -135.21, 28.45 296.48, 84.97 -57.15, -29.77 in-in in 7.6756 Saltbr-in 2.7452 HRD-in -84.66, -44.43 68.53, 7.81 in-in-out SNCiio in-out ActLoopNT-in 2.9218 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -119.94, 35.04 APE9-dihe-in -66.46, 139.38 APE8-dihe-in -79.29, 77.36 APE8-rot-na 30.63 APE67-dihe-in -76.81, -5.82 -62.53, -27.62 APE12-dist-na 11.2208 APE11-dist-na 12.9738 APE10-dist-na 10.2444 APE9-dist-in 6.6658 None PTR1034,PTR1035 PTR1034,PTR1035 XRAY 1.93 0.204 0.247 B 302.0 282.0 8 31 31 0 [[583, 847], [875, 1151]] 2.0 4ivd Homo sapiens TYR_JAK1-2_HUMAN TYR 2.2e-87 298.6 2.0 259.0 258.0 1020 1021 1022 1024 1026 908 925 929 1000 1002 1001 1003.0 1063 1051 1046 1045 1044 1043 1042 1041 1040 957 Tyrosine-protein kinase JAK1

PDB: 4IVD — TYR JAK1_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name