PDB: 4IVB — TYR JAK1_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 2 100.0% 4IVBB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR JAK1-2 JAK1_HUMAN 4IVBA P23458 854 1154 1154.0 1J5:61201 Type1 Inactive DFGin 6.4461 13.3982 ABAminus -120.37, 8.79 -154.43, 145.03 -134.59, 25.95 296.41, 85.72 -59.41, -26.27 in-in in 7.7771 Saltbr-in 2.6073 HRD-in -81.27, -49.76 73.46, 5.83 in-in-out SNCiio in-out ActLoopNT-in 2.9009 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -103.65, 36.69 APE9-dihe-in -67.09, 139.5 APE8-dihe-in -78.95, 74.88 APE8-rot-na 31.26 APE67-dihe-in -75.42, -5.51 -58.71, -32.55 APE12-dist-na 11.2148 APE11-dist-na 12.9349 APE10-dist-na 10.3112 APE9-dist-in 6.7806 None PTR1034,PTR1035 PTR1034,PTR1035 XRAY 1.9 0.183 0.221 A 302.0 292.0 9 31 31 0 [[583, 847], [875, 1151]] 2.0 4ivb TYR_JAK1-2_HUMAN TYR 2.2e-87 298.6 2.0 259.0 258.0 1020 1021 1022 1024 1026 908 925 929 1000 1002 1001 1003.0 1063 1051 1046 1045 1044 1043 1042 1041 1040 957 Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 4IVBB P23458 865 1154 1154.0 1J5:61201 Type1 Inactive DFGin 6.4294 13.4146 ABAminus -116.62, 7.74 -154.57, 143.33 -132.65, 26.65 294.75, 85.72 -57.0, -32.17 in-in in 7.7125 Saltbr-in 2.6507 HRD-in -82.29, -46.68 69.34, 6.53 in-in-out SNCiio in-out ActLoopNT-in 2.8948 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -108.2, 32.35 APE9-dihe-in -63.44, 138.0 APE8-dihe-in -78.25, 77.26 APE8-rot-na 32.13 APE67-dihe-in -75.77, -2.93 -62.98, -29.79 APE12-dist-na 11.2627 APE11-dist-na 12.9835 APE10-dist-na 10.306 APE9-dist-in 6.7691 None PTR1034,PTR1035 PTR1034,PTR1035 XRAY 1.9 0.183 0.221 B 302.0 282.0 8 31 31 0 [[583, 847], [875, 1151]] 2.0 4ivb TYR_JAK1-2_HUMAN TYR 2.2e-87 298.6 2.0 259.0 258.0 1020 1021 1022 1024 1026 908 925 929 1000 1002 1001 1003.0 1063 1051 1046 1045 1044 1043 1042 1041 1040 957 Tyrosine-protein kinase JAK1

PDB: 4IVB — TYR JAK1_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 2 100.0% 4IVBB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR JAK1-2 JAK1_HUMAN 4IVBA P23458 854 1154 1154.0 1J5:61201 Type1 Inactive DFGin 6.4461 13.3982 ABAminus -120.37, 8.79 -154.43, 145.03 -134.59, 25.95 296.41, 85.72 -59.41, -26.27 in-in in 7.7771 Saltbr-in 2.6073 HRD-in -81.27, -49.76 73.46, 5.83 in-in-out SNCiio in-out ActLoopNT-in 2.9009 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -103.65, 36.69 APE9-dihe-in -67.09, 139.5 APE8-dihe-in -78.95, 74.88 APE8-rot-na 31.26 APE67-dihe-in -75.42, -5.51 -58.71, -32.55 APE12-dist-na 11.2148 APE11-dist-na 12.9349 APE10-dist-na 10.3112 APE9-dist-in 6.7806 None PTR1034,PTR1035 PTR1034,PTR1035 XRAY 1.9 0.183 0.221 A 302.0 292.0 9 31 31 0 [[583, 847], [875, 1151]] 2.0 4ivb Homo sapiens TYR_JAK1-2_HUMAN TYR 2.2e-87 298.6 2.0 259.0 258.0 1020 1021 1022 1024 1026 908 925 929 1000 1002 1001 1003.0 1063 1051 1046 1045 1044 1043 1042 1041 1040 957 Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 4IVBB P23458 865 1154 1154.0 1J5:61201 Type1 Inactive DFGin 6.4294 13.4146 ABAminus -116.62, 7.74 -154.57, 143.33 -132.65, 26.65 294.75, 85.72 -57.0, -32.17 in-in in 7.7125 Saltbr-in 2.6507 HRD-in -82.29, -46.68 69.34, 6.53 in-in-out SNCiio in-out ActLoopNT-in 2.8948 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -108.2, 32.35 APE9-dihe-in -63.44, 138.0 APE8-dihe-in -78.25, 77.26 APE8-rot-na 32.13 APE67-dihe-in -75.77, -2.93 -62.98, -29.79 APE12-dist-na 11.2627 APE11-dist-na 12.9835 APE10-dist-na 10.306 APE9-dist-in 6.7691 None PTR1034,PTR1035 PTR1034,PTR1035 XRAY 1.9 0.183 0.221 B 302.0 282.0 8 31 31 0 [[583, 847], [875, 1151]] 2.0 4ivb Homo sapiens TYR_JAK1-2_HUMAN TYR 2.2e-87 298.6 2.0 259.0 258.0 1020 1021 1022 1024 1026 908 925 929 1000 1002 1001 1003.0 1063 1051 1046 1045 1044 1043 1042 1041 1040 957 Tyrosine-protein kinase JAK1

PDB: 4IVB — TYR JAK1_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name