PDB: 4I5C — TYR JAK1_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 2 100.0% 4I5CA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR JAK1-2 JAK1_HUMAN 4I5CA P23458 865 1154 1154.0 C5I:61201 Type1 Inactive DFGin 6.372 13.0985 ABAminus -114.74, 13.12 -159.95, 138.51 -132.46, 27.57 300.19, 86.09 -57.95, -29.46 in-in in 7.6484 Saltbr-in 2.6628 HRD-in -72.51, -44.79 66.5, 0.54 in-in-out SNCiio in-out ActLoopNT-in 2.903 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -124.02, 33.91 APE9-dihe-in -66.46, 131.24 APE8-dihe-in -75.55, 75.28 APE8-rot-na 31.15 APE67-dihe-in -75.41, -9.49 -50.0, -34.68 APE12-dist-na 11.2602 APE11-dist-na 13.3407 APE10-dist-na 10.1945 APE9-dist-in 6.774 None PTR1034,PTR1035 PTR1034,PTR1035 XRAY 2.1 0.193 0.245 A 302.0 281.0 9 31 30 1 [[583, 847], [875, 1151]] 2.0 4i5c TYR_JAK1-2_HUMAN TYR 2.2e-87 298.6 2.0 259.0 258.0 1020 1021 1022 1024 1026 908 925 929 1000 1002 1001 1003.0 1063 1051 1046 1045 1044 1043 1042 1041 1040 957 Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 4I5CB P23458 854 1154 1154.0 C5I:61205 Type1 Inactive DFGin 6.2884 13.0623 ABAminus -117.66, 20.22 -158.68, 137.22 -131.37, 22.03 299.16, 87.56 -52.78, -31.38 in-in in 7.784 Saltbr-in 2.5861 HRD-in -74.37, -52.31 71.43, 0.95 in-in-out SNCiio in-out ActLoopNT-in 2.9476 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -101.41, 21.23 APE9-dihe-in -58.7, 133.33 APE8-dihe-in -78.45, 70.87 APE8-rot-na 28.87 APE67-dihe-in -73.75, -3.17 -47.7, -37.18 APE12-dist-na 11.1462 APE11-dist-na 13.1938 APE10-dist-na 10.0316 APE9-dist-in 6.8402 None PTR1034,PTR1035 PTR1034,PTR1035 XRAY 2.1 0.193 0.245 B 302.0 292.0 9 31 31 0 [[583, 847], [875, 1151]] 2.0 4i5c TYR_JAK1-2_HUMAN TYR 2.2e-87 298.6 2.0 259.0 258.0 1020 1021 1022 1024 1026 908 925 929 1000 1002 1001 1003.0 1063 1051 1046 1045 1044 1043 1042 1041 1040 957 Tyrosine-protein kinase JAK1

PDB: 4I5C — TYR JAK1_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 2 100.0% 4I5CA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR JAK1-2 JAK1_HUMAN 4I5CA P23458 865 1154 1154.0 C5I:61201 Type1 Inactive DFGin 6.372 13.0985 ABAminus -114.74, 13.12 -159.95, 138.51 -132.46, 27.57 300.19, 86.09 -57.95, -29.46 in-in in 7.6484 Saltbr-in 2.6628 HRD-in -72.51, -44.79 66.5, 0.54 in-in-out SNCiio in-out ActLoopNT-in 2.903 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -124.02, 33.91 APE9-dihe-in -66.46, 131.24 APE8-dihe-in -75.55, 75.28 APE8-rot-na 31.15 APE67-dihe-in -75.41, -9.49 -50.0, -34.68 APE12-dist-na 11.2602 APE11-dist-na 13.3407 APE10-dist-na 10.1945 APE9-dist-in 6.774 None PTR1034,PTR1035 PTR1034,PTR1035 XRAY 2.1 0.193 0.245 A 302.0 281.0 9 31 30 1 [[583, 847], [875, 1151]] 2.0 4i5c Homo sapiens TYR_JAK1-2_HUMAN TYR 2.2e-87 298.6 2.0 259.0 258.0 1020 1021 1022 1024 1026 908 925 929 1000 1002 1001 1003.0 1063 1051 1046 1045 1044 1043 1042 1041 1040 957 Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 4I5CB P23458 854 1154 1154.0 C5I:61205 Type1 Inactive DFGin 6.2884 13.0623 ABAminus -117.66, 20.22 -158.68, 137.22 -131.37, 22.03 299.16, 87.56 -52.78, -31.38 in-in in 7.784 Saltbr-in 2.5861 HRD-in -74.37, -52.31 71.43, 0.95 in-in-out SNCiio in-out ActLoopNT-in 2.9476 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -101.41, 21.23 APE9-dihe-in -58.7, 133.33 APE8-dihe-in -78.45, 70.87 APE8-rot-na 28.87 APE67-dihe-in -73.75, -3.17 -47.7, -37.18 APE12-dist-na 11.1462 APE11-dist-na 13.1938 APE10-dist-na 10.0316 APE9-dist-in 6.8402 None PTR1034,PTR1035 PTR1034,PTR1035 XRAY 2.1 0.193 0.245 B 302.0 292.0 9 31 31 0 [[583, 847], [875, 1151]] 2.0 4i5c Homo sapiens TYR_JAK1-2_HUMAN TYR 2.2e-87 298.6 2.0 259.0 258.0 1020 1021 1022 1024 1026 908 925 929 1000 1002 1001 1003.0 1063 1051 1046 1045 1044 1043 1042 1041 1040 957 Tyrosine-protein kinase JAK1

PDB: 4I5C — TYR JAK1_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name