Hover over column headers for tooltip help
| Group | Gene | SwissprotID | PDB | UniprotID | First_obs_res | Last_obs_res | Length_Unp | Ligand | Ligand_type | Activity_label | Spatial_label | Phe_Glu4_dis | Phe_Lys_dis | Dihedral_label | XDFG φ,ψ |
DFG-Asp φ,ψ |
DFG-Phe φ,ψ |
DFG-Phe χ1,χ2 |
DFG-Gly φ,ψ |
ChelixSaltbr_label | Chelix_label | Lys_Glu_dis | Saltbr_label | LysNZ_GluOE_dis | HRD_label | His φ,ψ | Arg φ,ψ | SNC_label | SNCpymol_label | ActLoop_label | ActLoopNT_label | DFG6_XHRD_dis | ActLoopCT_label | APEtype | APEdihe_label | APEdist_label | APE10_dihe_label | APE10 φ,ψ | APE9_dihe_label | APE9 φ,ψ | APE8_dihe_label | APE8 φ,ψ | APE8_rotamer_label | APE8 χ1 | APE67_label | APE6 φ,ψ | APE7 φ,ψ | APE12_dist_label | APE12_DFG4_dis | APE11_dist_label | APE11_DFG4_dis | APE10_dist_label | APE10_DFG4_dis | APE9_dist_label | APE9_Arg_dis | Chain_mut | Chain_phos | Modified_aa | Method | Resolution | Rvalue | FreeRvalue | Chain_id | ChainLen | Ordered_residues | DomainBreak | ActLoopLength | ActLoopResolvedResidues | ActLoopDisorderedResidues | Kinase_domains_Unp | N_Kinase_domains_Unp | pdb | Kincore_name | hmm | Evalue | Score | hmmbeg | hmmend | hmmlen | XDFGnum | DFGnum | PHEnum | DFG4num | DFG6num | LYSnum | GLUnum | GLU4num | XHRDnum | ARGnum | HRDnum | HRDaspnum | aFaspnum | APEnum | APE6num | APE7num | APE8num | APE9num | APE10num | APE11num | APE12num | Hinge1num | Protein_name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| TYR | EGFR | EGFR_HUMAN | 4I24A | P00533 | 700 | 1014 | 1210.0 | 1C9:9001 | Type1 | Inactive | DFGin | 5.661 | 16.446 | BLBtrans | -124.79, -177.97 | 65.95, 19.32 | -65.94, 134.77 | 167.42, 77.24 | 100.69, -25.94 | out-out | out | 13.775 | Saltbr-out | 12.829 | HRD-in | -83.3, -47.74 | 80.82, -14.46 | out-out-out | SNCooo | out-out | ActLoopNT-out | 6.554 | ActLoopCT-out | TYR | APEdihe_nniai | APEdist_aaao | APE10-dihe-none | 999.0, 999.0 | APE9-dihe-none | 999.0, 124.29 | APE8-dihe-in | -74.66, 58.68 | APE8-rot-na | 28.63 | APE67-dihe-in | -76.18, -6.25 | -49.37, -41.47 | APE12-dist-na | 999.0 | APE11-dist-na | 999.0 | APE10-dist-na | 999.0 | APE9-dist-out | 8.306 | T790M | None | None | XRAY | 1.8 | 0.21 | 0.239 | A | 329 | 295 | 20 | 0 | 0 | 13 | [[712, 970]] | 1.0 | 4i24 | TYR_EGFR_HUMAN | TYR | 8.2e-88 | 300.1 | 3 | 259 | 257 | 854 | 855 | 856 | 858 | 860 | 745 | 762 | 766 | 834 | 836 | 835 | 837 | 896 | 884 | 879 | 878 | 877 | 876 | 875 | 874 | 873 | 791 | Epidermal growth factor receptor |
| TYR | EGFR | EGFR_HUMAN | 4I24B | P00533 | 700 | 1014 | 1210.0 | 1C9:9001 | Type1 | Inactive | DFGin | 5.538 | 16.502 | BLBtrans | -127.49, -179.81 | 73.27, 11.54 | -60.91, 132.74 | 167.82, 75.33 | 94.21, -14.75 | out-out | out | 14.01 | Saltbr-out | 12.566 | HRD-in | -82.33, -49.07 | 80.92, -16.04 | out-out-out | SNCooo | out-out | ActLoopNT-out | 6.75 | ActLoopCT-out | TYR | APEdihe_oiiai | APEdist_aaai | APE10-dihe-out | -77.49, -14.51 | APE9-dihe-in | -107.27, 109.9 | APE8-dihe-in | -79.94, 72.64 | APE8-rot-na | 30.26 | APE67-dihe-in | -75.43, -3.71 | -52.62, -43.52 | APE12-dist-na | 999.0 | APE11-dist-na | 13.81 | APE10-dist-na | 9.903 | APE9-dist-in | 7.489 | T790M | None | None | XRAY | 1.8 | 0.21 | 0.239 | B | 329 | 304 | 11 | 0 | 0 | 11 | [[712, 970]] | 1.0 | 4i24 | TYR_EGFR_HUMAN | TYR | 8.2e-88 | 300.1 | 3 | 259 | 257 | 854 | 855 | 856 | 858 | 860 | 745 | 762 | 766 | 834 | 836 | 835 | 837 | 896 | 884 | 879 | 878 | 877 | 876 | 875 | 874 | 873 | 791 | Epidermal growth factor receptor |
Hover over column headers for tooltip help
| Group | Gene | SwissprotID | PDB | UniprotID | First_obs_res | Last_obs_res | Length_Unp | Ligand | Ligand_type | Activity_label | Spatial_label | Phe_Glu4_dis | Phe_Lys_dis | Dihedral_label | XDFG φ,ψ |
DFG-Asp φ,ψ |
DFG-Phe φ,ψ |
DFG-Phe χ1,χ2 |
DFG-Gly φ,ψ |
ChelixSaltbr_label | Chelix_label | Lys_Glu_dis | Saltbr_label | LysNZ_GluOE_dis | HRD_label | His φ,ψ | Arg φ,ψ | SNC_label | SNCpymol_label | ActLoop_label | ActLoopNT_label | DFG6_XHRD_dis | ActLoopCT_label | APEtype | APEdihe_label | APEdist_label | APE10_dihe_label | APE10 φ,ψ | APE9_dihe_label | APE9 φ,ψ | APE8_dihe_label | APE8 φ,ψ | APE8_rotamer_label | APE8 χ1 | APE67_label | APE6 φ,ψ | APE7 φ,ψ | APE12_dist_label | APE12_DFG4_dis | APE11_dist_label | APE11_DFG4_dis | APE10_dist_label | APE10_DFG4_dis | APE9_dist_label | APE9_Arg_dis | Chain_mut | Chain_phos | Modified_aa | Method | Resolution | Rvalue | FreeRvalue | Chain_id | ChainLen | Ordered_residues | DomainBreak | ActLoopLength | ActLoopResolvedResidues | ActLoopDisorderedResidues | Kinase_domains_Unp | N_Kinase_domains_Unp | pdb | Species | Kincore_name | hmm | Evalue | Score | hmmbeg | hmmend | hmmlen | XDFGnum | DFGnum | PHEnum | DFG4num | DFG6num | LYSnum | GLUnum | GLU4num | XHRDnum | ARGnum | HRDnum | HRDaspnum | aFaspnum | APEnum | APE6num | APE7num | APE8num | APE9num | APE10num | APE11num | APE12num | Hinge1num | Protein_name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| TYR | EGFR | EGFR_HUMAN | 4I24A | P00533 | 700 | 1014 | 1210.0 | 1C9:9001 | Type1 | Inactive | DFGin | 5.661 | 16.446 | BLBtrans | -124.79, -177.97 | 65.95, 19.32 | -65.94, 134.77 | 167.42, 77.24 | 100.69, -25.94 | out-out | out | 13.775 | Saltbr-out | 12.829 | HRD-in | -83.3, -47.74 | 80.82, -14.46 | out-out-out | SNCooo | out-out | ActLoopNT-out | 6.554 | ActLoopCT-out | TYR | APEdihe_nniai | APEdist_aaao | APE10-dihe-none | 999.0, 999.0 | APE9-dihe-none | 999.0, 124.29 | APE8-dihe-in | -74.66, 58.68 | APE8-rot-na | 28.63 | APE67-dihe-in | -76.18, -6.25 | -49.37, -41.47 | APE12-dist-na | 999.0 | APE11-dist-na | 999.0 | APE10-dist-na | 999.0 | APE9-dist-out | 8.306 | T790M | None | None | XRAY | 1.8 | 0.21 | 0.239 | A | 329 | 295 | 20 | 0 | 0 | 13 | [[712, 970]] | 1.0 | 4i24 | Homo sapiens | TYR_EGFR_HUMAN | TYR | 8.2e-88 | 300.1 | 3 | 259 | 257 | 854 | 855 | 856 | 858 | 860 | 745 | 762 | 766 | 834 | 836 | 835 | 837 | 896 | 884 | 879 | 878 | 877 | 876 | 875 | 874 | 873 | 791 | Epidermal growth factor receptor |
| TYR | EGFR | EGFR_HUMAN | 4I24B | P00533 | 700 | 1014 | 1210.0 | 1C9:9001 | Type1 | Inactive | DFGin | 5.538 | 16.502 | BLBtrans | -127.49, -179.81 | 73.27, 11.54 | -60.91, 132.74 | 167.82, 75.33 | 94.21, -14.75 | out-out | out | 14.01 | Saltbr-out | 12.566 | HRD-in | -82.33, -49.07 | 80.92, -16.04 | out-out-out | SNCooo | out-out | ActLoopNT-out | 6.75 | ActLoopCT-out | TYR | APEdihe_oiiai | APEdist_aaai | APE10-dihe-out | -77.49, -14.51 | APE9-dihe-in | -107.27, 109.9 | APE8-dihe-in | -79.94, 72.64 | APE8-rot-na | 30.26 | APE67-dihe-in | -75.43, -3.71 | -52.62, -43.52 | APE12-dist-na | 999.0 | APE11-dist-na | 13.81 | APE10-dist-na | 9.903 | APE9-dist-in | 7.489 | T790M | None | None | XRAY | 1.8 | 0.21 | 0.239 | B | 329 | 304 | 11 | 0 | 0 | 11 | [[712, 970]] | 1.0 | 4i24 | Homo sapiens | TYR_EGFR_HUMAN | TYR | 8.2e-88 | 300.1 | 3 | 259 | 257 | 854 | 855 | 856 | 858 | 860 | 745 | 762 | 766 | 834 | 836 | 835 | 837 | 896 | 884 | 879 | 878 | 877 | 876 | 875 | 874 | 873 | 791 | Epidermal growth factor receptor |
| Spatial label | Dihedral label | Number of Chains | Percent | Representative |
|---|
Hover over column headers for tooltip help
| Group | Gene | SwissprotID | PDB | UniprotID | First_obs_res | Last_obs_res | Length_Unp | Ligand | Ligand_type | Activity_label | Spatial_label | Phe_Glu4_dis | Phe_Lys_dis | Dihedral_label | XDFG φ,ψ |
DFG-Asp φ,ψ |
DFG-Phe φ,ψ |
DFG-Phe χ1,χ2 |
DFG-Gly φ,ψ |
ChelixSaltbr_label | Chelix_label | Lys_Glu_dis | Saltbr_label | LysNZ_GluOE_dis | HRD_label | His φ,ψ | Arg φ,ψ | SNC_label | SNCpymol_label | ActLoop_label | ActLoopNT_label | DFG6_XHRD_dis | ActLoopCT_label | APEtype | APEdihe_label | APEdist_label | APE10_dihe_label | APE10 φ,ψ | APE9_dihe_label | APE9 φ,ψ | APE8_dihe_label | APE8 φ,ψ | APE8_rotamer_label | APE8 χ1 | APE67_label | APE6 φ,ψ | APE7 φ,ψ | APE12_dist_label | APE12_DFG4_dis | APE11_dist_label | APE11_DFG4_dis | APE10_dist_label | APE10_DFG4_dis | APE9_dist_label | APE9_Arg_dis | Chain_mut | Chain_phos | Modified_aa | Method | Resolution | Rvalue | FreeRvalue | Chain_id | ChainLen | Ordered_residues | DomainBreak | ActLoopLength | ActLoopResolvedResidues | ActLoopDisorderedResidues | Kinase_domains_Unp | N_Kinase_domains_Unp | pdb | Species | Kincore_name | hmm | Evalue | Score | hmmbeg | hmmend | hmmlen | XDFGnum | DFGnum | PHEnum | DFG4num | DFG6num | LYSnum | GLUnum | GLU4num | XHRDnum | ARGnum | HRDnum | HRDaspnum | aFaspnum | APEnum | APE6num | APE7num | APE8num | APE9num | APE10num | APE11num | APE12num | Hinge1num | Protein_name |
|---|