PDB: 4HGE — TYR JAK2_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 2 100.0% 4HGEA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR JAK2-2 JAK2_HUMAN 4HGEA O60674 843 1132 1132.0 15V:1201 Type1 Inactive DFGin 6.12 13.3223 ABAminus -121.19, -0.59 -151.44, 140.08 -132.37, 31.16 296.92, 93.91 -59.01, -29.78 in-in in 8.5102 Saltbr-in 2.6509 HRD-in -71.02, -46.89 72.34, 4.2 in-in-in SNCiii in-in ActLoopNT-in 2.8163 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -97.36, 116.11 APE9-dihe-in -94.64, 140.5 APE8-dihe-in -78.26, 68.86 APE8-rot-na 33.18 APE67-dihe-in -79.92, -6.13 -58.48, -24.37 APE12-dist-na 13.1329 APE11-dist-na 12.3352 APE10-dist-na 12.6137 APE9-dist-in 7.8996 None PTR1007,PTR1008 PTR1007,PTR1008 XRAY 2.3 0.182 0.227 A 300.0 286.0 4 31 31 0 [[545, 807], [849, 1125]] 2.0 4hge TYR_JAK2-2_HUMAN TYR 2.6e-87 298.4 1.0 260.0 260.0 993 994 995 997 999 882 898 902 973 975 974 976.0 1036 1024 1019 1018 1017 1016 1015 1014 1013 930 Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 4HGEB O60674 839 1132 1132.0 15V:1201 Type1 Inactive DFGin 6.4139 13.619 ABAminus -123.27, 3.39 -144.34, 141.84 -131.47, 30.21 289.8, 89.09 -61.76, -21.14 in-in in 8.47 Saltbr-in 2.7549 HRD-in -75.48, -44.42 74.95, -13.38 in-in-in SNCiii in-in ActLoopNT-in 2.7745 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -80.96, 159.38 APE9-dihe-in -121.56, 128.25 APE8-dihe-in -83.16, 76.08 APE8-rot-na 32.14 APE67-dihe-in -81.69, -3.64 -63.01, -27.28 APE12-dist-na 7.6125 APE11-dist-na 9.1957 APE10-dist-na 10.9268 APE9-dist-in 7.5698 None PTR1007,PTR1008 PTR1007,PTR1008 XRAY 2.3 0.182 0.227 B 300.0 290.0 4 31 31 0 [[545, 807], [849, 1125]] 2.0 4hge TYR_JAK2-2_HUMAN TYR 2.6e-87 298.4 1.0 260.0 260.0 993 994 995 997 999 882 898 902 973 975 974 976.0 1036 1024 1019 1018 1017 1016 1015 1014 1013 930 Tyrosine-protein kinase JAK2

PDB: 4HGE — TYR JAK2_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 2 100.0% 4HGEA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR JAK2-2 JAK2_HUMAN 4HGEA O60674 843 1132 1132.0 15V:1201 Type1 Inactive DFGin 6.12 13.3223 ABAminus -121.19, -0.59 -151.44, 140.08 -132.37, 31.16 296.92, 93.91 -59.01, -29.78 in-in in 8.5102 Saltbr-in 2.6509 HRD-in -71.02, -46.89 72.34, 4.2 in-in-in SNCiii in-in ActLoopNT-in 2.8163 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -97.36, 116.11 APE9-dihe-in -94.64, 140.5 APE8-dihe-in -78.26, 68.86 APE8-rot-na 33.18 APE67-dihe-in -79.92, -6.13 -58.48, -24.37 APE12-dist-na 13.1329 APE11-dist-na 12.3352 APE10-dist-na 12.6137 APE9-dist-in 7.8996 None PTR1007,PTR1008 PTR1007,PTR1008 XRAY 2.3 0.182 0.227 A 300.0 286.0 4 31 31 0 [[545, 807], [849, 1125]] 2.0 4hge Homo sapiens TYR_JAK2-2_HUMAN TYR 2.6e-87 298.4 1.0 260.0 260.0 993 994 995 997 999 882 898 902 973 975 974 976.0 1036 1024 1019 1018 1017 1016 1015 1014 1013 930 Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 4HGEB O60674 839 1132 1132.0 15V:1201 Type1 Inactive DFGin 6.4139 13.619 ABAminus -123.27, 3.39 -144.34, 141.84 -131.47, 30.21 289.8, 89.09 -61.76, -21.14 in-in in 8.47 Saltbr-in 2.7549 HRD-in -75.48, -44.42 74.95, -13.38 in-in-in SNCiii in-in ActLoopNT-in 2.7745 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -80.96, 159.38 APE9-dihe-in -121.56, 128.25 APE8-dihe-in -83.16, 76.08 APE8-rot-na 32.14 APE67-dihe-in -81.69, -3.64 -63.01, -27.28 APE12-dist-na 7.6125 APE11-dist-na 9.1957 APE10-dist-na 10.9268 APE9-dist-in 7.5698 None PTR1007,PTR1008 PTR1007,PTR1008 XRAY 2.3 0.182 0.227 B 300.0 290.0 4 31 31 0 [[545, 807], [849, 1125]] 2.0 4hge Homo sapiens TYR_JAK2-2_HUMAN TYR 2.6e-87 298.4 1.0 260.0 260.0 993 994 995 997 999 882 898 902 973 975 974 976.0 1036 1024 1019 1018 1017 1016 1015 1014 1013 930 Tyrosine-protein kinase JAK2

PDB: 4HGE — TYR JAK2_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name