PDB: 4EI4 — TYR JAK1_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 2 100.0% 4EI4B
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR JAK1-2 JAK1_HUMAN 4EI4A P23458 854 1154 1154.0 0Q2:61201 Type1 Inactive DFGin 6.3615 13.4524 ABAminus -125.08, 21.55 -162.93, 136.7 -132.47, 29.54 298.16, 82.51 -65.62, -22.07 in-in in 7.843 Saltbr-in 2.6125 HRD-in -82.16, -48.37 72.58, 5.29 in-in-out SNCiio in-out ActLoopNT-in 2.7441 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -105.53, 42.94 APE9-dihe-in -71.49, 136.49 APE8-dihe-in -77.62, 74.63 APE8-rot-na 31.88 APE67-dihe-in -76.69, -5.39 -62.91, -28.92 APE12-dist-na 10.9829 APE11-dist-na 12.7533 APE10-dist-na 10.2586 APE9-dist-in 6.7838 None PTR1034,PTR1035 PTR1034,PTR1035 XRAY 2.22 0.202 0.239 A 302.0 290.0 11 31 31 0 [[583, 847], [875, 1151]] 2.0 4ei4 TYR_JAK1-2_HUMAN TYR 2.2e-87 298.6 2.0 259.0 258.0 1020 1021 1022 1024 1026 908 925 929 1000 1002 1001 1003.0 1063 1051 1046 1045 1044 1043 1042 1041 1040 957 Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 4EI4B P23458 865 1154 1154.0 0Q2:61201 Type1 Inactive DFGin 6.3821 13.5185 ABAminus -120.19, 16.13 -160.02, 140.78 -136.52, 31.88 292.39, 84.5 -65.63, -28.61 in-in in 7.8532 Saltbr-in 2.8267 HRD-in -84.06, -46.22 68.02, 6.16 in-in-out SNCiio in-out ActLoopNT-in 2.7517 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -108.4, 38.28 APE9-dihe-in -67.47, 135.5 APE8-dihe-in -75.19, 75.25 APE8-rot-na 28.78 APE67-dihe-in -75.9, -4.89 -57.78, -34.83 APE12-dist-na 11.0547 APE11-dist-na 12.6874 APE10-dist-na 10.2359 APE9-dist-in 6.7889 None PTR1034,PTR1035 PTR1034,PTR1035 XRAY 2.22 0.202 0.239 B 302.0 282.0 8 31 31 0 [[583, 847], [875, 1151]] 2.0 4ei4 TYR_JAK1-2_HUMAN TYR 2.2e-87 298.6 2.0 259.0 258.0 1020 1021 1022 1024 1026 908 925 929 1000 1002 1001 1003.0 1063 1051 1046 1045 1044 1043 1042 1041 1040 957 Tyrosine-protein kinase JAK1

PDB: 4EI4 — TYR JAK1_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 2 100.0% 4EI4B
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR JAK1-2 JAK1_HUMAN 4EI4A P23458 854 1154 1154.0 0Q2:61201 Type1 Inactive DFGin 6.3615 13.4524 ABAminus -125.08, 21.55 -162.93, 136.7 -132.47, 29.54 298.16, 82.51 -65.62, -22.07 in-in in 7.843 Saltbr-in 2.6125 HRD-in -82.16, -48.37 72.58, 5.29 in-in-out SNCiio in-out ActLoopNT-in 2.7441 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -105.53, 42.94 APE9-dihe-in -71.49, 136.49 APE8-dihe-in -77.62, 74.63 APE8-rot-na 31.88 APE67-dihe-in -76.69, -5.39 -62.91, -28.92 APE12-dist-na 10.9829 APE11-dist-na 12.7533 APE10-dist-na 10.2586 APE9-dist-in 6.7838 None PTR1034,PTR1035 PTR1034,PTR1035 XRAY 2.22 0.202 0.239 A 302.0 290.0 11 31 31 0 [[583, 847], [875, 1151]] 2.0 4ei4 Homo sapiens TYR_JAK1-2_HUMAN TYR 2.2e-87 298.6 2.0 259.0 258.0 1020 1021 1022 1024 1026 908 925 929 1000 1002 1001 1003.0 1063 1051 1046 1045 1044 1043 1042 1041 1040 957 Tyrosine-protein kinase JAK1
TYR JAK1-2 JAK1_HUMAN 4EI4B P23458 865 1154 1154.0 0Q2:61201 Type1 Inactive DFGin 6.3821 13.5185 ABAminus -120.19, 16.13 -160.02, 140.78 -136.52, 31.88 292.39, 84.5 -65.63, -28.61 in-in in 7.8532 Saltbr-in 2.8267 HRD-in -84.06, -46.22 68.02, 6.16 in-in-out SNCiio in-out ActLoopNT-in 2.7517 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -108.4, 38.28 APE9-dihe-in -67.47, 135.5 APE8-dihe-in -75.19, 75.25 APE8-rot-na 28.78 APE67-dihe-in -75.9, -4.89 -57.78, -34.83 APE12-dist-na 11.0547 APE11-dist-na 12.6874 APE10-dist-na 10.2359 APE9-dist-in 6.7889 None PTR1034,PTR1035 PTR1034,PTR1035 XRAY 2.22 0.202 0.239 B 302.0 282.0 8 31 31 0 [[583, 847], [875, 1151]] 2.0 4ei4 Homo sapiens TYR_JAK1-2_HUMAN TYR 2.2e-87 298.6 2.0 259.0 258.0 1020 1021 1022 1024 1026 908 925 929 1000 1002 1001 1003.0 1063 1051 1046 1045 1044 1043 1042 1041 1040 957 Tyrosine-protein kinase JAK1

PDB: 4EI4 — TYR JAK1_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name