PDB: 4E6Q — TYR JAK2_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 2 100.0% 4E6QA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR JAK2-2 JAK2_HUMAN 4E6QA O60674 835 1132 1132.0 0NV:1201 Type1 Inactive DFGin 6.2691 13.4502 ABAminus -126.67, 13.67 -142.89, 143.88 -137.27, 22.15 296.58, 95.03 -64.63, -19.34 in-in in 8.3656 Saltbr-in 2.8741 HRD-in -63.97, -49.26 71.25, 9.0 in-in-out SNCiio in-out ActLoopNT-in 2.7328 ActLoopCT-out TYR APEdihe_iiiai APEdist_aaao APE10-dihe-in -67.76, 142.09 APE9-dihe-in -117.85, 160.32 APE8-dihe-in -76.9, 79.46 APE8-rot-na 30.98 APE67-dihe-in -84.05, -2.56 -64.72, -24.34 APE12-dist-na 13.7531 APE11-dist-na 13.3495 APE10-dist-na 14.0785 APE9-dist-out 8.1979 Q853R,Y931F,D939E PTR1007,PTR1008 PTR1007,PTR1008 XRAY 1.948 0.189 0.234 A 298.0 298.0 0 31 31 0 [[545, 807], [849, 1125]] 2.0 4e6q TYR_JAK2-2_HUMAN TYR 4.9e-87 297.5 1.0 260.0 260.0 993 994 995 997 999 882 898 902 973 975 974 976.0 1036 1024 1019 1018 1017 1016 1015 1014 1013 930 Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 4E6QB O60674 835 1132 1132.0 0NV:1201 Type1 Inactive DFGin 6.3092 13.3934 ABAminus -126.92, 5.36 -155.12, 144.98 -131.94, 23.19 295.89, 95.38 -67.11, -25.79 in-in in 8.1185 Saltbr-in 2.3735 HRD-in -66.33, -47.39 73.85, -0.29 in-in-out SNCiio in-out ActLoopNT-in 2.9834 ActLoopCT-out TYR APEdihe_iiiai APEdist_aaao APE10-dihe-in -76.02, 138.29 APE9-dihe-in -102.23, 152.61 APE8-dihe-in -79.57, 76.43 APE8-rot-na 29.69 APE67-dihe-in -80.89, 2.35 -56.64, -31.57 APE12-dist-na 13.8601 APE11-dist-na 12.97 APE10-dist-na 13.9823 APE9-dist-out 8.4564 Q853R,Y931F,D939E PTR1007,PTR1008 PTR1007,PTR1008 XRAY 1.948 0.189 0.234 B 298.0 298.0 0 31 31 0 [[545, 807], [849, 1125]] 2.0 4e6q TYR_JAK2-2_HUMAN TYR 4.9e-87 297.5 1.0 260.0 260.0 993 994 995 997 999 882 898 902 973 975 974 976.0 1036 1024 1019 1018 1017 1016 1015 1014 1013 930 Tyrosine-protein kinase JAK2

PDB: 4E6Q — TYR JAK2_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 2 100.0% 4E6QA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR JAK2-2 JAK2_HUMAN 4E6QA O60674 835 1132 1132.0 0NV:1201 Type1 Inactive DFGin 6.2691 13.4502 ABAminus -126.67, 13.67 -142.89, 143.88 -137.27, 22.15 296.58, 95.03 -64.63, -19.34 in-in in 8.3656 Saltbr-in 2.8741 HRD-in -63.97, -49.26 71.25, 9.0 in-in-out SNCiio in-out ActLoopNT-in 2.7328 ActLoopCT-out TYR APEdihe_iiiai APEdist_aaao APE10-dihe-in -67.76, 142.09 APE9-dihe-in -117.85, 160.32 APE8-dihe-in -76.9, 79.46 APE8-rot-na 30.98 APE67-dihe-in -84.05, -2.56 -64.72, -24.34 APE12-dist-na 13.7531 APE11-dist-na 13.3495 APE10-dist-na 14.0785 APE9-dist-out 8.1979 Q853R,Y931F,D939E PTR1007,PTR1008 PTR1007,PTR1008 XRAY 1.948 0.189 0.234 A 298.0 298.0 0 31 31 0 [[545, 807], [849, 1125]] 2.0 4e6q Homo sapiens TYR_JAK2-2_HUMAN TYR 4.9e-87 297.5 1.0 260.0 260.0 993 994 995 997 999 882 898 902 973 975 974 976.0 1036 1024 1019 1018 1017 1016 1015 1014 1013 930 Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 4E6QB O60674 835 1132 1132.0 0NV:1201 Type1 Inactive DFGin 6.3092 13.3934 ABAminus -126.92, 5.36 -155.12, 144.98 -131.94, 23.19 295.89, 95.38 -67.11, -25.79 in-in in 8.1185 Saltbr-in 2.3735 HRD-in -66.33, -47.39 73.85, -0.29 in-in-out SNCiio in-out ActLoopNT-in 2.9834 ActLoopCT-out TYR APEdihe_iiiai APEdist_aaao APE10-dihe-in -76.02, 138.29 APE9-dihe-in -102.23, 152.61 APE8-dihe-in -79.57, 76.43 APE8-rot-na 29.69 APE67-dihe-in -80.89, 2.35 -56.64, -31.57 APE12-dist-na 13.8601 APE11-dist-na 12.97 APE10-dist-na 13.9823 APE9-dist-out 8.4564 Q853R,Y931F,D939E PTR1007,PTR1008 PTR1007,PTR1008 XRAY 1.948 0.189 0.234 B 298.0 298.0 0 31 31 0 [[545, 807], [849, 1125]] 2.0 4e6q Homo sapiens TYR_JAK2-2_HUMAN TYR 4.9e-87 297.5 1.0 260.0 260.0 993 994 995 997 999 882 898 902 973 975 974 976.0 1036 1024 1019 1018 1017 1016 1015 1014 1013 930 Tyrosine-protein kinase JAK2

PDB: 4E6Q — TYR JAK2_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name