PDB: 4CNH — TYR ALK_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 2 100.0% 4CNHB
All chains - renumbered by
Uniprot PDB Alignment

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Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR ALK ALK_HUMAN 4CNHA Q9UM73 1094 1402 1620.0 3U9:2402 Type1 Inactive DFGin 6.328 15.046 ABAminus -121.41, -13.5 -134.76, 134.27 -127.13, 24.83 291.86, 80.94 -58.37, -37.06 in-out in 7.905 Saltbr-out 4.916 HRD-in -72.36, -47.54 81.36, -5.81 out-out-none SNCoon out-none ActLoopNT-out 7.025 ActLoopCT-none TYR APEdihe_niiai APEdist_aaai APE10-dihe-none 999.0, 36.87 APE9-dihe-in -64.44, 124.84 APE8-dihe-in -71.68, 78.76 APE8-rot-na 25.36 APE67-dihe-in -71.29, -8.43 -50.25, -44.65 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 7.445 APE9-dist-in 6.811 None None None XRAY 1.9 0.206 0.25 A 327 286 23 0 0 10 [[1116, 1385]] 1.0 4cnh TYR_ALK_HUMAN TYR 1.4e-90 309.1 1 260 260 1269 1270 1271 1273 1275 1150 1167 1171 1246 1248 1247 1249 1311 1299 1294 1293 1292 1291 1290 1289 1288 1197 ALK tyrosine kinase receptor
TYR ALK ALK_HUMAN 4CNHB Q9UM73 1093 1401 1620.0 3U9:2401,3U9:2402 Type1,Allosteric Inactive DFGin 4.339 12.327 ABAminus -115.59, -14.06 -164.87, 163.73 -86.41, -10.43 302.46, 115.44 53.37, -130.64 in-in in 8.072 Saltbr-in 2.629 HRD-in -84.33, -49.79 83.6, -11.29 in-out-out SNCioo out-out ActLoopNT-out 8.549 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaao APE10-dihe-out -91.6, -17.34 APE9-dihe-in -73.51, 138.4 APE8-dihe-in -77.48, 68.43 APE8-rot-na 27.84 APE67-dihe-in -66.22, -13.37 -69.94, -19.9 APE12-dist-na 12.784 APE11-dist-na 13.464 APE10-dist-na 8.385 APE9-dist-out 8.684 None None None XRAY 1.9 0.206 0.25 B 327 294 15 0 0 5 [[1116, 1385]] 1.0 4cnh TYR_ALK_HUMAN TYR 1.4e-90 309.1 1 260 260 1269 1270 1271 1273 1275 1150 1167 1171 1246 1248 1247 1249 1311 1299 1294 1293 1292 1291 1290 1289 1288 1197 ALK tyrosine kinase receptor

PDB: 4CNH — TYR ALK_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 2 100.0% 4CNHB
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR ALK ALK_HUMAN 4CNHA Q9UM73 1094 1402 1620.0 3U9:2402 Type1 Inactive DFGin 6.328 15.046 ABAminus -121.41, -13.5 -134.76, 134.27 -127.13, 24.83 291.86, 80.94 -58.37, -37.06 in-out in 7.905 Saltbr-out 4.916 HRD-in -72.36, -47.54 81.36, -5.81 out-out-none SNCoon out-none ActLoopNT-out 7.025 ActLoopCT-none TYR APEdihe_niiai APEdist_aaai APE10-dihe-none 999.0, 36.87 APE9-dihe-in -64.44, 124.84 APE8-dihe-in -71.68, 78.76 APE8-rot-na 25.36 APE67-dihe-in -71.29, -8.43 -50.25, -44.65 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 7.445 APE9-dist-in 6.811 None None None XRAY 1.9 0.206 0.25 A 327 286 23 0 0 10 [[1116, 1385]] 1.0 4cnh Homo sapiens TYR_ALK_HUMAN TYR 1.4e-90 309.1 1 260 260 1269 1270 1271 1273 1275 1150 1167 1171 1246 1248 1247 1249 1311 1299 1294 1293 1292 1291 1290 1289 1288 1197 ALK tyrosine kinase receptor
TYR ALK ALK_HUMAN 4CNHB Q9UM73 1093 1401 1620.0 3U9:2401,3U9:2402 Type1,Allosteric Inactive DFGin 4.339 12.327 ABAminus -115.59, -14.06 -164.87, 163.73 -86.41, -10.43 302.46, 115.44 53.37, -130.64 in-in in 8.072 Saltbr-in 2.629 HRD-in -84.33, -49.79 83.6, -11.29 in-out-out SNCioo out-out ActLoopNT-out 8.549 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaao APE10-dihe-out -91.6, -17.34 APE9-dihe-in -73.51, 138.4 APE8-dihe-in -77.48, 68.43 APE8-rot-na 27.84 APE67-dihe-in -66.22, -13.37 -69.94, -19.9 APE12-dist-na 12.784 APE11-dist-na 13.464 APE10-dist-na 8.385 APE9-dist-out 8.684 None None None XRAY 1.9 0.206 0.25 B 327 294 15 0 0 5 [[1116, 1385]] 1.0 4cnh Homo sapiens TYR_ALK_HUMAN TYR 1.4e-90 309.1 1 260 260 1269 1270 1271 1273 1275 1150 1167 1171 1246 1248 1247 1249 1311 1299 1294 1293 1292 1291 1290 1289 1288 1197 ALK tyrosine kinase receptor

PDB: 4CNH — TYR ALK_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name