PDB: 4ASX — TKL AVR2A_HUMAN

Total number of chains: 2
Active chains: 1
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 4ASXB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL ACVR2A AVR2A_HUMAN 4ASXA P27037 191 486 513.0 6OJ:61487 Type1 Active DFGin 7.5848 13.7119 BLAminus -124.23, 158.41 76.6, 95.75 -110.56, 27.08 303.84, 107.63 -64.07, -28.35 in-in in 8.1512 Saltbr-in 2.681 HRD-in -83.4, -48.78 80.27, 1.37 in-in-in SNCiii in-in ActLoopNT-in 2.9143 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -98.14, -19.06 APE9-dihe-na -92.2, -158.06 APE8-dihe-in -89.26, 125.94 APE8-rot-in 297.71 APE67-dihe-in -63.22, -23.86 -54.78, -47.48 APE12-dist-in 10.9349 APE11-dist-in 12.4424 APE10-dist-in 6.3997 APE9-dist-in 3.4817 None None None XRAY 2.05 0.188 0.225 A 322.0 295.0 1 30 29 1 [[192, 481]] 1.0 4asx TKL_ACVR2A_HUMAN TKL 3.5e-83 285.1 2.0 266.0 265.0 339 340 341 343 345 219 232 236 319 321 320 322.0 386 369 364 363 362 361 360 359 358 268 Activin receptor type-2A
TKL ACVR2A AVR2A_HUMAN 4ASXB P27037 191 486 513.0 6OJ:61487 Type1 Inactive DFGin 7.649 13.9339 BLAminus -125.14, 162.25 70.64, 90.86 -105.86, 23.27 300.55, 102.55 -60.78, -32.52 in-in in 8.1876 Saltbr-in 2.8127 HRD-in -76.15, -47.44 73.25, 3.45 in-in-out SNCiio in-out ActLoopNT-in 2.9141 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iooi APE10-dihe-na -130.56, 171.14 APE9-dihe-na -89.41, -155.19 APE8-dihe-in -83.7, 128.51 APE8-rot-in 306.98 APE67-dihe-in -59.4, -19.9 -51.63, -52.75 APE12-dist-in 10.1183 APE11-dist-out 5.9218 APE10-dist-out 8.9293 APE9-dist-in 3.6405 None None None XRAY 2.05 0.188 0.225 B 322.0 296.0 0 30 30 0 [[192, 481]] 1.0 4asx TKL_ACVR2A_HUMAN TKL 3.5e-83 285.1 2.0 266.0 265.0 339 340 341 343 345 219 232 236 319 321 320 322.0 386 369 364 363 362 361 360 359 358 268 Activin receptor type-2A

PDB: 4ASX — TKL AVR2A_HUMAN

Total number of chains: 2
Active chains: 1
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 4ASXB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL ACVR2A AVR2A_HUMAN 4ASXA P27037 191 486 513.0 6OJ:61487 Type1 Active DFGin 7.5848 13.7119 BLAminus -124.23, 158.41 76.6, 95.75 -110.56, 27.08 303.84, 107.63 -64.07, -28.35 in-in in 8.1512 Saltbr-in 2.681 HRD-in -83.4, -48.78 80.27, 1.37 in-in-in SNCiii in-in ActLoopNT-in 2.9143 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -98.14, -19.06 APE9-dihe-na -92.2, -158.06 APE8-dihe-in -89.26, 125.94 APE8-rot-in 297.71 APE67-dihe-in -63.22, -23.86 -54.78, -47.48 APE12-dist-in 10.9349 APE11-dist-in 12.4424 APE10-dist-in 6.3997 APE9-dist-in 3.4817 None None None XRAY 2.05 0.188 0.225 A 322.0 295.0 1 30 29 1 [[192, 481]] 1.0 4asx Homo sapiens TKL_ACVR2A_HUMAN TKL 3.5e-83 285.1 2.0 266.0 265.0 339 340 341 343 345 219 232 236 319 321 320 322.0 386 369 364 363 362 361 360 359 358 268 Activin receptor type-2A
TKL ACVR2A AVR2A_HUMAN 4ASXB P27037 191 486 513.0 6OJ:61487 Type1 Inactive DFGin 7.649 13.9339 BLAminus -125.14, 162.25 70.64, 90.86 -105.86, 23.27 300.55, 102.55 -60.78, -32.52 in-in in 8.1876 Saltbr-in 2.8127 HRD-in -76.15, -47.44 73.25, 3.45 in-in-out SNCiio in-out ActLoopNT-in 2.9141 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iooi APE10-dihe-na -130.56, 171.14 APE9-dihe-na -89.41, -155.19 APE8-dihe-in -83.7, 128.51 APE8-rot-in 306.98 APE67-dihe-in -59.4, -19.9 -51.63, -52.75 APE12-dist-in 10.1183 APE11-dist-out 5.9218 APE10-dist-out 8.9293 APE9-dist-in 3.6405 None None None XRAY 2.05 0.188 0.225 B 322.0 296.0 0 30 30 0 [[192, 481]] 1.0 4asx Homo sapiens TKL_ACVR2A_HUMAN TKL 3.5e-83 285.1 2.0 266.0 265.0 339 340 341 343 345 219 232 236 319 321 320 322.0 386 369 364 363 362 361 360 359 358 268 Activin receptor type-2A

PDB: 4ASX — TKL AVR2A_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name