PDB: 3V5L — TYR ITK_HUMAN

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAplus 4 100.0% 3V5LC
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR ITK ITK_HUMAN 3V5LA Q08881 357 616 620.0 0G1:60701 Type1 Inactive DFGin 4.1338 14.7047 BLAplus -115.85, 171.01 48.27, 46.07 -96.05, 11.31 58.96, 91.61 -107.31, 8.54 out-none out 10.1449 Saltbr-none 999.0 HRD-in -65.69, -47.42 74.14, -16.58 none-none-none SNCnnn none-none ActLoopNT-none 999.0 ActLoopCT-none TYR APEdihe_nnnai APEdist_aaan APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 999.0 APE8-dihe-none 999.0, 142.05 APE8-rot-na 332.57 APE67-dihe-in -62.15, -19.85 -69.15, -18.57 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-none 999.0 None None None XRAY 1.86 0.232 0.252 A 266.0 238.0 22 29 13 16 [[363, 614]] 1.0 3v5l TYR_ITK_HUMAN TYR 9.4e-93 316.2 1.0 260.0 260.0 499 500 501 503 505 391 406 410 479 481 480 482.0 540 528 523 522 521 520 519 518 517 436 Tyrosine-protein kinase ITK/TSK
TYR ITK ITK_HUMAN 3V5LB Q08881 357 619 620.0 0G1:60701 Type1 Inactive DFGin 4.1399 14.6499 BLAplus -115.25, 172.45 47.57, 47.21 -97.73, 8.05 59.86, 89.65 -107.55, 11.69 out-out out 10.0753 Saltbr-out 5.3889 HRD-in -66.97, -47.64 75.37, -19.95 out-none-none SNConn none-none ActLoopNT-none 999.0 ActLoopCT-none TYR APEdihe_nnnai APEdist_aaan APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 999.0 APE8-dihe-none 999.0, -28.51 APE8-rot-na 26.38 APE67-dihe-in -61.19, -18.82 -58.23, -34.87 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-none 999.0 None None None XRAY 1.86 0.232 0.252 B 266.0 239.0 24 29 13 16 [[363, 614]] 1.0 3v5l TYR_ITK_HUMAN TYR 9.4e-93 316.2 1.0 260.0 260.0 499 500 501 503 505 391 406 410 479 481 480 482.0 540 528 523 522 521 520 519 518 517 436 Tyrosine-protein kinase ITK/TSK
TYR ITK ITK_HUMAN 3V5LC Q08881 357 616 620.0 0G1:60701 Type1 Inactive DFGin 4.151 14.49 BLAplus -119.43, 171.57 47.86, 45.98 -95.4, 6.02 56.69, 90.24 -103.84, 4.9 in-out in 9.9164 Saltbr-out 5.4292 HRD-in -67.67, -52.97 78.54, -20.18 out-none-out SNCono none-out ActLoopNT-none 999.0 ActLoopCT-out TYR APEdihe_nnoai APEdist_aaao APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 134.05 APE8-dihe-out -64.27, -25.66 APE8-rot-na 343.98 APE67-dihe-in -64.94, -21.62 -63.54, -24.83 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-out 11.2825 None None None XRAY 1.86 0.232 0.252 C 266.0 242.0 18 29 14 15 [[363, 614]] 1.0 3v5l TYR_ITK_HUMAN TYR 9.4e-93 316.2 1.0 260.0 260.0 499 500 501 503 505 391 406 410 479 481 480 482.0 540 528 523 522 521 520 519 518 517 436 Tyrosine-protein kinase ITK/TSK
TYR ITK ITK_HUMAN 3V5LD Q08881 357 619 620.0 0G1:60701 Type1 Inactive DFGin 4.1221 14.5366 BLAplus -118.73, 170.46 50.59, 44.65 -96.3, 5.17 58.81, 89.99 -103.3, 10.97 out-out out 10.0127 Saltbr-out 5.4138 HRD-in -69.59, -48.92 76.64, -24.59 out-none-out SNCono none-out ActLoopNT-none 999.0 ActLoopCT-out TYR APEdihe_nnoai APEdist_aaao APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 84.06 APE8-dihe-out -96.47, -61.68 APE8-rot-na 21.65 APE67-dihe-in -60.91, -18.81 -64.24, -17.65 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-out 11.5568 None None None XRAY 1.86 0.232 0.252 D 266.0 244.0 19 29 13 16 [[363, 614]] 1.0 3v5l TYR_ITK_HUMAN TYR 9.4e-93 316.2 1.0 260.0 260.0 499 500 501 503 505 391 406 410 479 481 480 482.0 540 528 523 522 521 520 519 518 517 436 Tyrosine-protein kinase ITK/TSK

PDB: 3V5L — TYR ITK_HUMAN

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAplus 4 100.0% 3V5LC
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR ITK ITK_HUMAN 3V5LA Q08881 357 616 620.0 0G1:60701 Type1 Inactive DFGin 4.1338 14.7047 BLAplus -115.85, 171.01 48.27, 46.07 -96.05, 11.31 58.96, 91.61 -107.31, 8.54 out-none out 10.1449 Saltbr-none 999.0 HRD-in -65.69, -47.42 74.14, -16.58 none-none-none SNCnnn none-none ActLoopNT-none 999.0 ActLoopCT-none TYR APEdihe_nnnai APEdist_aaan APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 999.0 APE8-dihe-none 999.0, 142.05 APE8-rot-na 332.57 APE67-dihe-in -62.15, -19.85 -69.15, -18.57 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-none 999.0 None None None XRAY 1.86 0.232 0.252 A 266.0 238.0 22 29 13 16 [[363, 614]] 1.0 3v5l Homo sapiens TYR_ITK_HUMAN TYR 9.4e-93 316.2 1.0 260.0 260.0 499 500 501 503 505 391 406 410 479 481 480 482.0 540 528 523 522 521 520 519 518 517 436 Tyrosine-protein kinase ITK/TSK
TYR ITK ITK_HUMAN 3V5LB Q08881 357 619 620.0 0G1:60701 Type1 Inactive DFGin 4.1399 14.6499 BLAplus -115.25, 172.45 47.57, 47.21 -97.73, 8.05 59.86, 89.65 -107.55, 11.69 out-out out 10.0753 Saltbr-out 5.3889 HRD-in -66.97, -47.64 75.37, -19.95 out-none-none SNConn none-none ActLoopNT-none 999.0 ActLoopCT-none TYR APEdihe_nnnai APEdist_aaan APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 999.0 APE8-dihe-none 999.0, -28.51 APE8-rot-na 26.38 APE67-dihe-in -61.19, -18.82 -58.23, -34.87 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-none 999.0 None None None XRAY 1.86 0.232 0.252 B 266.0 239.0 24 29 13 16 [[363, 614]] 1.0 3v5l Homo sapiens TYR_ITK_HUMAN TYR 9.4e-93 316.2 1.0 260.0 260.0 499 500 501 503 505 391 406 410 479 481 480 482.0 540 528 523 522 521 520 519 518 517 436 Tyrosine-protein kinase ITK/TSK
TYR ITK ITK_HUMAN 3V5LC Q08881 357 616 620.0 0G1:60701 Type1 Inactive DFGin 4.151 14.49 BLAplus -119.43, 171.57 47.86, 45.98 -95.4, 6.02 56.69, 90.24 -103.84, 4.9 in-out in 9.9164 Saltbr-out 5.4292 HRD-in -67.67, -52.97 78.54, -20.18 out-none-out SNCono none-out ActLoopNT-none 999.0 ActLoopCT-out TYR APEdihe_nnoai APEdist_aaao APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 134.05 APE8-dihe-out -64.27, -25.66 APE8-rot-na 343.98 APE67-dihe-in -64.94, -21.62 -63.54, -24.83 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-out 11.2825 None None None XRAY 1.86 0.232 0.252 C 266.0 242.0 18 29 14 15 [[363, 614]] 1.0 3v5l Homo sapiens TYR_ITK_HUMAN TYR 9.4e-93 316.2 1.0 260.0 260.0 499 500 501 503 505 391 406 410 479 481 480 482.0 540 528 523 522 521 520 519 518 517 436 Tyrosine-protein kinase ITK/TSK
TYR ITK ITK_HUMAN 3V5LD Q08881 357 619 620.0 0G1:60701 Type1 Inactive DFGin 4.1221 14.5366 BLAplus -118.73, 170.46 50.59, 44.65 -96.3, 5.17 58.81, 89.99 -103.3, 10.97 out-out out 10.0127 Saltbr-out 5.4138 HRD-in -69.59, -48.92 76.64, -24.59 out-none-out SNCono none-out ActLoopNT-none 999.0 ActLoopCT-out TYR APEdihe_nnoai APEdist_aaao APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 84.06 APE8-dihe-out -96.47, -61.68 APE8-rot-na 21.65 APE67-dihe-in -60.91, -18.81 -64.24, -17.65 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-out 11.5568 None None None XRAY 1.86 0.232 0.252 D 266.0 244.0 19 29 13 16 [[363, 614]] 1.0 3v5l Homo sapiens TYR_ITK_HUMAN TYR 9.4e-93 316.2 1.0 260.0 260.0 499 500 501 503 505 391 406 410 479 481 480 482.0 540 528 523 522 521 520 519 518 517 436 Tyrosine-protein kinase ITK/TSK

PDB: 3V5L — TYR ITK_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name