PDB: 3QQU — TYR IGF1R_HUMAN

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin None 2 50.0% 3QQUD
DFGin BLAminus 1 25.0% 3QQUC
DFGin BLBminus 1 25.0% 3QQUA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR IGF1R IGF1R_HUMAN 3QQUC P08069 989 1285 1367.0 01P:60001 Type1 Inactive DFGin 8.3183 16.8697 BLAminus -97.01, 150.34 14.49, 98.68 -65.56, 26.06 281.91, 75.71 -140.07, 16.5 in-in in 9.1914 Saltbr-in 3.5942 HRD-out -77.97, 136.61 -108.26, 0.31 in-out-in SNCioi out-in ActLoopNT-out 16.8575 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -74.41, 127.29 APE9-dihe-in -133.08, 155.06 APE8-dihe-in -87.24, 64.19 APE8-rot-na 38.0 APE67-dihe-in -67.35, -9.92 -53.34, -43.26 APE12-dist-na 22.8313 APE11-dist-na 18.0406 APE10-dist-na 14.3988 APE9-dist-in 7.4378 None None None XRAY 2.9 0.273 0.302 C 301.0 293.0 4 30 30 0 [[999, 1268]] 1.0 3qqu TYR_IGF1R_HUMAN TYR 1.8e-95 325.1 1.0 260.0 260.0 1152 1153 1154 1156 1158 1033 1050 1054 1132 1134 1133 1135.0 1194 1182 1177 1176 1175 1174 1173 1172 1171 1080 Insulin-like growth factor 1 receptor
TYR IGF1R IGF1R_HUMAN 3QQUA P08069 991 1285 1367.0 01P:60001 Type1 Inactive DFGin 7.0177 15.7776 BLBminus -115.26, 159.62 28.18, 96.19 -42.42, 112.88 288.43, 150.16 68.34, -45.79 in-out in 9.091 Saltbr-out 5.0929 HRD-out -66.07, 145.48 -122.95, 8.59 out-out-in SNCooi out-in ActLoopNT-out 16.9553 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -69.25, 118.57 APE9-dihe-in -132.55, 144.54 APE8-dihe-in -85.92, 76.47 APE8-rot-na 33.89 APE67-dihe-in -71.18, -0.86 -64.59, -36.6 APE12-dist-na 20.8612 APE11-dist-na 16.489 APE10-dist-na 12.4873 APE9-dist-in 7.3544 None None None XRAY 2.9 0.273 0.302 A 301.0 285.0 10 30 30 0 [[999, 1268]] 1.0 3qqu TYR_IGF1R_HUMAN TYR 1.8e-95 325.1 1.0 260.0 260.0 1152 1153 1154 1156 1158 1033 1050 1054 1132 1134 1133 1135.0 1194 1182 1177 1176 1175 1174 1173 1172 1171 1080 Insulin-like growth factor 1 receptor
TYR IGF1R IGF1R_HUMAN 3QQUB P08069 988 1286 1367.0 01P:60001 Type1 Inactive DFGin 7.3126 15.8493 None -33.42, 160.47 -37.99, 116.49 -33.99, 105.39 285.12, 147.4 61.19, -16.27 in-out in 9.1403 Saltbr-out 5.1324 HRD-out -74.87, 134.07 -112.64, 23.07 out-out-in SNCooi out-in ActLoopNT-out 16.4502 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -68.73, 125.53 APE9-dihe-in -129.43, 153.07 APE8-dihe-in -94.91, 67.38 APE8-rot-na 36.24 APE67-dihe-in -82.46, 4.52 -51.63, -28.48 APE12-dist-na 20.8733 APE11-dist-na 16.3058 APE10-dist-na 12.6306 APE9-dist-in 7.0517 None None None XRAY 2.9 0.273 0.302 B 301.0 288.0 11 30 30 0 [[999, 1268]] 1.0 3qqu TYR_IGF1R_HUMAN TYR 1.8e-95 325.1 1.0 260.0 260.0 1152 1153 1154 1156 1158 1033 1050 1054 1132 1134 1133 1135.0 1194 1182 1177 1176 1175 1174 1173 1172 1171 1080 Insulin-like growth factor 1 receptor
TYR IGF1R IGF1R_HUMAN 3QQUD P08069 989 1285 1367.0 01P:60001 Type1 Inactive DFGin 7.8652 16.3418 None -72.27, 173.4 -41.63, 112.37 -69.49, 2.91 294.86, 82.49 -113.94, 14.31 in-out in 9.3296 Saltbr-out 4.3315 HRD-out -89.46, 130.4 -100.59, 1.17 out-out-out SNCooo out-out ActLoopNT-out 17.3649 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out 71.55, 69.22 APE9-dihe-in -124.37, 159.91 APE8-dihe-in -89.12, 68.21 APE8-rot-na 38.62 APE67-dihe-in -73.08, -17.7 -59.12, -27.53 APE12-dist-na 21.9404 APE11-dist-na 19.125 APE10-dist-na 15.1883 APE9-dist-in 7.4577 None None None XRAY 2.9 0.273 0.302 D 301.0 292.0 5 30 30 0 [[999, 1268]] 1.0 3qqu TYR_IGF1R_HUMAN TYR 1.8e-95 325.1 1.0 260.0 260.0 1152 1153 1154 1156 1158 1033 1050 1054 1132 1134 1133 1135.0 1194 1182 1177 1176 1175 1174 1173 1172 1171 1080 Insulin-like growth factor 1 receptor

PDB: 3QQU — TYR IGF1R_HUMAN

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin None 2 50.0% 3QQUD
DFGin BLAminus 1 25.0% 3QQUC
DFGin BLBminus 1 25.0% 3QQUA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR IGF1R IGF1R_HUMAN 3QQUC P08069 989 1285 1367.0 01P:60001 Type1 Inactive DFGin 8.3183 16.8697 BLAminus -97.01, 150.34 14.49, 98.68 -65.56, 26.06 281.91, 75.71 -140.07, 16.5 in-in in 9.1914 Saltbr-in 3.5942 HRD-out -77.97, 136.61 -108.26, 0.31 in-out-in SNCioi out-in ActLoopNT-out 16.8575 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -74.41, 127.29 APE9-dihe-in -133.08, 155.06 APE8-dihe-in -87.24, 64.19 APE8-rot-na 38.0 APE67-dihe-in -67.35, -9.92 -53.34, -43.26 APE12-dist-na 22.8313 APE11-dist-na 18.0406 APE10-dist-na 14.3988 APE9-dist-in 7.4378 None None None XRAY 2.9 0.273 0.302 C 301.0 293.0 4 30 30 0 [[999, 1268]] 1.0 3qqu Homo sapiens TYR_IGF1R_HUMAN TYR 1.8e-95 325.1 1.0 260.0 260.0 1152 1153 1154 1156 1158 1033 1050 1054 1132 1134 1133 1135.0 1194 1182 1177 1176 1175 1174 1173 1172 1171 1080 Insulin-like growth factor 1 receptor
TYR IGF1R IGF1R_HUMAN 3QQUA P08069 991 1285 1367.0 01P:60001 Type1 Inactive DFGin 7.0177 15.7776 BLBminus -115.26, 159.62 28.18, 96.19 -42.42, 112.88 288.43, 150.16 68.34, -45.79 in-out in 9.091 Saltbr-out 5.0929 HRD-out -66.07, 145.48 -122.95, 8.59 out-out-in SNCooi out-in ActLoopNT-out 16.9553 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -69.25, 118.57 APE9-dihe-in -132.55, 144.54 APE8-dihe-in -85.92, 76.47 APE8-rot-na 33.89 APE67-dihe-in -71.18, -0.86 -64.59, -36.6 APE12-dist-na 20.8612 APE11-dist-na 16.489 APE10-dist-na 12.4873 APE9-dist-in 7.3544 None None None XRAY 2.9 0.273 0.302 A 301.0 285.0 10 30 30 0 [[999, 1268]] 1.0 3qqu Homo sapiens TYR_IGF1R_HUMAN TYR 1.8e-95 325.1 1.0 260.0 260.0 1152 1153 1154 1156 1158 1033 1050 1054 1132 1134 1133 1135.0 1194 1182 1177 1176 1175 1174 1173 1172 1171 1080 Insulin-like growth factor 1 receptor
TYR IGF1R IGF1R_HUMAN 3QQUB P08069 988 1286 1367.0 01P:60001 Type1 Inactive DFGin 7.3126 15.8493 None -33.42, 160.47 -37.99, 116.49 -33.99, 105.39 285.12, 147.4 61.19, -16.27 in-out in 9.1403 Saltbr-out 5.1324 HRD-out -74.87, 134.07 -112.64, 23.07 out-out-in SNCooi out-in ActLoopNT-out 16.4502 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -68.73, 125.53 APE9-dihe-in -129.43, 153.07 APE8-dihe-in -94.91, 67.38 APE8-rot-na 36.24 APE67-dihe-in -82.46, 4.52 -51.63, -28.48 APE12-dist-na 20.8733 APE11-dist-na 16.3058 APE10-dist-na 12.6306 APE9-dist-in 7.0517 None None None XRAY 2.9 0.273 0.302 B 301.0 288.0 11 30 30 0 [[999, 1268]] 1.0 3qqu Homo sapiens TYR_IGF1R_HUMAN TYR 1.8e-95 325.1 1.0 260.0 260.0 1152 1153 1154 1156 1158 1033 1050 1054 1132 1134 1133 1135.0 1194 1182 1177 1176 1175 1174 1173 1172 1171 1080 Insulin-like growth factor 1 receptor
TYR IGF1R IGF1R_HUMAN 3QQUD P08069 989 1285 1367.0 01P:60001 Type1 Inactive DFGin 7.8652 16.3418 None -72.27, 173.4 -41.63, 112.37 -69.49, 2.91 294.86, 82.49 -113.94, 14.31 in-out in 9.3296 Saltbr-out 4.3315 HRD-out -89.46, 130.4 -100.59, 1.17 out-out-out SNCooo out-out ActLoopNT-out 17.3649 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out 71.55, 69.22 APE9-dihe-in -124.37, 159.91 APE8-dihe-in -89.12, 68.21 APE8-rot-na 38.62 APE67-dihe-in -73.08, -17.7 -59.12, -27.53 APE12-dist-na 21.9404 APE11-dist-na 19.125 APE10-dist-na 15.1883 APE9-dist-in 7.4577 None None None XRAY 2.9 0.273 0.302 D 301.0 292.0 5 30 30 0 [[999, 1268]] 1.0 3qqu Homo sapiens TYR_IGF1R_HUMAN TYR 1.8e-95 325.1 1.0 260.0 260.0 1152 1153 1154 1156 1158 1033 1050 1054 1132 1134 1133 1135.0 1194 1182 1177 1176 1175 1174 1173 1172 1171 1080 Insulin-like growth factor 1 receptor

PDB: 3QQU — TYR IGF1R_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name