PDB: 3LZB — TYR EGFR_HUMAN

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 4 100.0% 3LZBA
All chains - renumbered by
Uniprot PDB Alignment

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Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR EGFR EGFR_HUMAN 3LZBA P00533 703 983 1210.0 ITI:60001 Type1.5_Back Inactive DFGin 4.413 14.113 BLBplus -125.13, 176.44 56.08, 40.39 -84.19, 136.21 42.68, 101.81 78.32, 7.67 out-out out 14.281 Saltbr-out 16.067 HRD-in -64.02, -64.87 94.19, -31.0 out-none-out SNCono none-out ActLoopNT-none 999.0 ActLoopCT-out TYR APEdihe_niiai APEdist_aaao APE10-dihe-none 999.0, 170.85 APE9-dihe-in -92.26, 121.26 APE8-dihe-in -64.31, 51.85 APE8-rot-na 8.36 APE67-dihe-in -68.59, -1.05 -39.19, -47.35 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 14.357 APE9-dist-out 8.223 V948R None None XRAY 2.7 0.206 0.257 A 327 265 16 0 0 16 [[712, 970]] 1.0 3lzb TYR_EGFR_HUMAN TYR 7.8e-88 300.1 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 3LZBB P00533 703 983 1210.0 ITI:60001 Type1.5_Back Inactive DFGin 4.381 13.959 BLBplus -119.7, -179.35 54.89, 41.32 -86.82, 133.57 41.54, 106.13 73.46, 9.05 out-out out 14.275 Saltbr-out 16.097 HRD-in -65.79, -60.12 87.79, -17.38 out-none-none SNConn none-none ActLoopNT-none 999.0 ActLoopCT-none TYR APEdihe_niiai APEdist_aaai APE10-dihe-none 999.0, 175.31 APE9-dihe-in -89.1, 120.24 APE8-dihe-in -68.59, 65.01 APE8-rot-na 30.46 APE67-dihe-in -68.36, -3.12 -48.63, -40.63 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 14.171 APE9-dist-in 7.817 V948R None None XRAY 2.7 0.206 0.257 B 327 265 16 0 0 16 [[712, 970]] 1.0 3lzb TYR_EGFR_HUMAN TYR 7.8e-88 300.1 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 3LZBC P00533 704 983 1210.0 ITI:60001 Type1.5_Back Inactive DFGin 4.388 14.034 BLBplus -132.56, 174.78 57.2, 36.27 -81.82, 140.08 44.1, 102.6 73.85, 8.44 out-out out 13.853 Saltbr-out 16.045 HRD-in -67.43, -53.65 76.74, -16.56 out-none-none SNConn none-none ActLoopNT-none 999.0 ActLoopCT-none TYR APEdihe_niiai APEdist_aaai APE10-dihe-none 999.0, 172.19 APE9-dihe-in -92.55, 117.86 APE8-dihe-in -70.59, 65.45 APE8-rot-na 30.7 APE67-dihe-in -69.07, -2.07 -45.86, -43.98 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 13.409 APE9-dist-in 7.638 V948R None None XRAY 2.7 0.206 0.257 C 327 259 21 0 0 16 [[712, 970]] 1.0 3lzb TYR_EGFR_HUMAN TYR 7.8e-88 300.1 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 3LZBD P00533 703 983 1210.0 ITI:60001 Type1.5_Back Inactive DFGin 4.542 14.207 BLBplus -128.51, 168.04 64.67, 28.61 -76.12, 143.44 45.13, 102.55 72.45, 3.46 out-out out 14.931 Saltbr-out 17.043 HRD-in -64.23, -56.15 80.94, -21.59 out-none-none SNConn none-none ActLoopNT-none 999.0 ActLoopCT-none TYR APEdihe_niiai APEdist_aaai APE10-dihe-none 999.0, -168.64 APE9-dihe-in -94.62, 117.93 APE8-dihe-in -68.62, 65.64 APE8-rot-na 31.36 APE67-dihe-in -68.52, -3.42 -48.32, -42.0 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 14.196 APE9-dist-in 7.812 V948R None None XRAY 2.7 0.206 0.257 D 327 261 20 0 0 16 [[712, 970]] 1.0 3lzb TYR_EGFR_HUMAN TYR 7.8e-88 300.1 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor

PDB: 3LZB — TYR EGFR_HUMAN

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 4 100.0% 3LZBA
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR EGFR EGFR_HUMAN 3LZBA P00533 703 983 1210.0 ITI:60001 Type1.5_Back Inactive DFGin 4.413 14.113 BLBplus -125.13, 176.44 56.08, 40.39 -84.19, 136.21 42.68, 101.81 78.32, 7.67 out-out out 14.281 Saltbr-out 16.067 HRD-in -64.02, -64.87 94.19, -31.0 out-none-out SNCono none-out ActLoopNT-none 999.0 ActLoopCT-out TYR APEdihe_niiai APEdist_aaao APE10-dihe-none 999.0, 170.85 APE9-dihe-in -92.26, 121.26 APE8-dihe-in -64.31, 51.85 APE8-rot-na 8.36 APE67-dihe-in -68.59, -1.05 -39.19, -47.35 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 14.357 APE9-dist-out 8.223 V948R None None XRAY 2.7 0.206 0.257 A 327 265 16 0 0 16 [[712, 970]] 1.0 3lzb Homo sapiens TYR_EGFR_HUMAN TYR 7.8e-88 300.1 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 3LZBB P00533 703 983 1210.0 ITI:60001 Type1.5_Back Inactive DFGin 4.381 13.959 BLBplus -119.7, -179.35 54.89, 41.32 -86.82, 133.57 41.54, 106.13 73.46, 9.05 out-out out 14.275 Saltbr-out 16.097 HRD-in -65.79, -60.12 87.79, -17.38 out-none-none SNConn none-none ActLoopNT-none 999.0 ActLoopCT-none TYR APEdihe_niiai APEdist_aaai APE10-dihe-none 999.0, 175.31 APE9-dihe-in -89.1, 120.24 APE8-dihe-in -68.59, 65.01 APE8-rot-na 30.46 APE67-dihe-in -68.36, -3.12 -48.63, -40.63 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 14.171 APE9-dist-in 7.817 V948R None None XRAY 2.7 0.206 0.257 B 327 265 16 0 0 16 [[712, 970]] 1.0 3lzb Homo sapiens TYR_EGFR_HUMAN TYR 7.8e-88 300.1 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 3LZBC P00533 704 983 1210.0 ITI:60001 Type1.5_Back Inactive DFGin 4.388 14.034 BLBplus -132.56, 174.78 57.2, 36.27 -81.82, 140.08 44.1, 102.6 73.85, 8.44 out-out out 13.853 Saltbr-out 16.045 HRD-in -67.43, -53.65 76.74, -16.56 out-none-none SNConn none-none ActLoopNT-none 999.0 ActLoopCT-none TYR APEdihe_niiai APEdist_aaai APE10-dihe-none 999.0, 172.19 APE9-dihe-in -92.55, 117.86 APE8-dihe-in -70.59, 65.45 APE8-rot-na 30.7 APE67-dihe-in -69.07, -2.07 -45.86, -43.98 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 13.409 APE9-dist-in 7.638 V948R None None XRAY 2.7 0.206 0.257 C 327 259 21 0 0 16 [[712, 970]] 1.0 3lzb Homo sapiens TYR_EGFR_HUMAN TYR 7.8e-88 300.1 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 3LZBD P00533 703 983 1210.0 ITI:60001 Type1.5_Back Inactive DFGin 4.542 14.207 BLBplus -128.51, 168.04 64.67, 28.61 -76.12, 143.44 45.13, 102.55 72.45, 3.46 out-out out 14.931 Saltbr-out 17.043 HRD-in -64.23, -56.15 80.94, -21.59 out-none-none SNConn none-none ActLoopNT-none 999.0 ActLoopCT-none TYR APEdihe_niiai APEdist_aaai APE10-dihe-none 999.0, -168.64 APE9-dihe-in -94.62, 117.93 APE8-dihe-in -68.62, 65.64 APE8-rot-na 31.36 APE67-dihe-in -68.52, -3.42 -48.32, -42.0 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 14.196 APE9-dist-in 7.812 V948R None None XRAY 2.7 0.206 0.257 D 327 261 20 0 0 16 [[712, 970]] 1.0 3lzb Homo sapiens TYR_EGFR_HUMAN TYR 7.8e-88 300.1 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor

PDB: 3LZB — TYR EGFR_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name