PDB: 3FUP — TYR JAK2_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 2 100.0% 3FUPA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR JAK2-2 JAK2_HUMAN 3FUPA O60674 843 1132 1132.0 MI1:1 Type1 Inactive DFGin 6.2247 13.4318 ABAminus -116.05, -10.27 -157.31, 141.86 -130.25, 26.52 298.67, 97.27 -56.05, -29.03 in-in in 8.5319 Saltbr-in 2.8127 HRD-in -69.41, -60.51 90.73, 3.04 in-in-in SNCiii in-in ActLoopNT-in 2.7879 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -103.46, 121.61 APE9-dihe-in -101.81, 146.65 APE8-dihe-in -75.99, 69.83 APE8-rot-na 29.05 APE67-dihe-in -81.62, -2.38 -64.51, -21.49 APE12-dist-na 12.3877 APE11-dist-na 13.1219 APE10-dist-na 12.9278 APE9-dist-in 7.8195 N1129Q PTR1007,PTR1008 PTR1007,PTR1008 XRAY 2.4 0.182 0.25 A 293.0 286.0 4 31 31 0 [[545, 807], [849, 1125]] 2.0 3fup TYR_JAK2-2_HUMAN TYR 2.4e-87 298.5 1.0 260.0 260.0 993 994 995 997 999 882 898 902 973 975 974 976.0 1036 1024 1019 1018 1017 1016 1015 1014 1013 930 Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 3FUPB O60674 840 1132 1132.0 MI1:1 Type1 Inactive DFGin 6.5155 13.5423 ABAminus -123.67, 7.61 -151.78, 141.72 -133.31, 23.64 288.75, 96.19 -52.65, -32.8 in-in in 8.2963 Saltbr-in 2.8068 HRD-in -70.48, -55.18 91.07, -4.94 in-in-in SNCiii in-in ActLoopNT-in 2.9235 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -118.61, 115.12 APE9-dihe-in -94.97, 142.02 APE8-dihe-in -78.58, 69.75 APE8-rot-na 27.0 APE67-dihe-in -74.68, 0.84 -67.13, -29.65 APE12-dist-na 12.7558 APE11-dist-na 12.3891 APE10-dist-na 12.2233 APE9-dist-in 7.7048 N1129Q PTR1007,PTR1008 PTR1007,PTR1008 XRAY 2.4 0.182 0.25 B 293.0 289.0 4 31 31 0 [[545, 807], [849, 1125]] 2.0 3fup TYR_JAK2-2_HUMAN TYR 2.4e-87 298.5 1.0 260.0 260.0 993 994 995 997 999 882 898 902 973 975 974 976.0 1036 1024 1019 1018 1017 1016 1015 1014 1013 930 Tyrosine-protein kinase JAK2

PDB: 3FUP — TYR JAK2_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 2 100.0% 3FUPA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR JAK2-2 JAK2_HUMAN 3FUPA O60674 843 1132 1132.0 MI1:1 Type1 Inactive DFGin 6.2247 13.4318 ABAminus -116.05, -10.27 -157.31, 141.86 -130.25, 26.52 298.67, 97.27 -56.05, -29.03 in-in in 8.5319 Saltbr-in 2.8127 HRD-in -69.41, -60.51 90.73, 3.04 in-in-in SNCiii in-in ActLoopNT-in 2.7879 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -103.46, 121.61 APE9-dihe-in -101.81, 146.65 APE8-dihe-in -75.99, 69.83 APE8-rot-na 29.05 APE67-dihe-in -81.62, -2.38 -64.51, -21.49 APE12-dist-na 12.3877 APE11-dist-na 13.1219 APE10-dist-na 12.9278 APE9-dist-in 7.8195 N1129Q PTR1007,PTR1008 PTR1007,PTR1008 XRAY 2.4 0.182 0.25 A 293.0 286.0 4 31 31 0 [[545, 807], [849, 1125]] 2.0 3fup Homo sapiens TYR_JAK2-2_HUMAN TYR 2.4e-87 298.5 1.0 260.0 260.0 993 994 995 997 999 882 898 902 973 975 974 976.0 1036 1024 1019 1018 1017 1016 1015 1014 1013 930 Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 3FUPB O60674 840 1132 1132.0 MI1:1 Type1 Inactive DFGin 6.5155 13.5423 ABAminus -123.67, 7.61 -151.78, 141.72 -133.31, 23.64 288.75, 96.19 -52.65, -32.8 in-in in 8.2963 Saltbr-in 2.8068 HRD-in -70.48, -55.18 91.07, -4.94 in-in-in SNCiii in-in ActLoopNT-in 2.9235 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -118.61, 115.12 APE9-dihe-in -94.97, 142.02 APE8-dihe-in -78.58, 69.75 APE8-rot-na 27.0 APE67-dihe-in -74.68, 0.84 -67.13, -29.65 APE12-dist-na 12.7558 APE11-dist-na 12.3891 APE10-dist-na 12.2233 APE9-dist-in 7.7048 N1129Q PTR1007,PTR1008 PTR1007,PTR1008 XRAY 2.4 0.182 0.25 B 293.0 289.0 4 31 31 0 [[545, 807], [849, 1125]] 2.0 3fup Homo sapiens TYR_JAK2-2_HUMAN TYR 2.4e-87 298.5 1.0 260.0 260.0 993 994 995 997 999 882 898 902 973 975 974 976.0 1036 1024 1019 1018 1017 1016 1015 1014 1013 930 Tyrosine-protein kinase JAK2

PDB: 3FUP — TYR JAK2_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name