PDB: 3ANR — CMGC DYR1A_HUMAN

Total number of chains: 4
Active chains: 1
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 4 100.0% 3ANRA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC DYRK1A DYR1A_HUMAN 3ANRA Q13627 134 481 763.0 HRM:1 Type1 Active DFGin 7.3952 14.8796 BLAminus -126.97, 175.57 62.29, 87.12 -103.96, 24.02 282.74, 80.66 -67.77, -18.58 in-in in 8.7055 Saltbr-in 2.9447 HRD-in -59.12, -43.08 70.29, -4.2 in-in-in SNCiii in-in ActLoopNT-in 2.803 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -124.86, 169.59 APE9-dihe-na 72.59, 157.32 APE8-dihe-in -74.37, 142.22 APE8-rot-in 294.27 APE67-dihe-in -55.49, -26.14 -45.5, -54.94 APE12-dist-in 13.813 APE11-dist-in 12.0606 APE10-dist-in 7.9549 APE9-dist-in 3.2535 None PTR321 PTR321 XRAY 2.6 0.232 0.264 A 368.0 343.0 5 25 25 0 [[159, 479]] 1.0 3anr CMGC_DYRK1A_HUMAN CMGC 9e-91 310.1 1.0 301.0 301.0 306 307 308 310 312 188 203 207 284 286 285 287.0 343 331 326 325 324 323 322 321 320 239 Dual specificity tyrosine-phosphorylation-regulated kinase 1A
CMGC DYRK1A DYR1A_HUMAN 3ANRB Q13627 133 481 763.0 HRM:1 Type1 Inactive DFGin 7.4555 14.9313 BLAminus -127.37, 175.29 64.18, 86.03 -102.43, 22.55 283.14, 80.72 -64.64, -20.73 in-in in 8.7327 Saltbr-in 2.8661 HRD-in -58.01, -41.76 68.55, -4.63 in-in-out SNCiio in-out ActLoopNT-in 2.9937 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iioi APE10-dihe-na -113.3, 162.51 APE9-dihe-na 75.38, 151.66 APE8-dihe-in -71.98, 142.21 APE8-rot-in 293.97 APE67-dihe-in -54.5, -26.35 -45.44, -54.76 APE12-dist-in 13.7489 APE11-dist-in 11.8941 APE10-dist-out 8.014 APE9-dist-in 3.315 None PTR321 PTR321 XRAY 2.6 0.232 0.264 B 368.0 343.0 6 25 25 0 [[159, 479]] 1.0 3anr CMGC_DYRK1A_HUMAN CMGC 9e-91 310.1 1.0 301.0 301.0 306 307 308 310 312 188 203 207 284 286 285 287.0 343 331 326 325 324 323 322 321 320 239 Dual specificity tyrosine-phosphorylation-regulated kinase 1A
CMGC DYRK1A DYR1A_HUMAN 3ANRC Q13627 134 481 763.0 HRM:1 Type1 Inactive DFGin 7.3517 14.8245 BLAminus -127.39, 175.73 63.91, 86.99 -105.92, 24.64 282.96, 79.27 -68.52, -18.05 in-in in 8.7205 Saltbr-in 2.9637 HRD-in -60.25, -41.86 68.21, -2.43 in-in-out SNCiio in-out ActLoopNT-in 2.9578 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oioi APE10-dihe-na -115.38, 158.82 APE9-dihe-na 80.57, 155.21 APE8-dihe-in -73.66, 142.81 APE8-rot-in 291.66 APE67-dihe-in -55.43, -28.06 -45.81, -53.64 APE12-dist-out 14.2127 APE11-dist-in 12.1151 APE10-dist-out 8.2585 APE9-dist-in 3.3346 None PTR321 PTR321 XRAY 2.6 0.232 0.264 C 368.0 338.0 10 25 25 0 [[159, 479]] 1.0 3anr CMGC_DYRK1A_HUMAN CMGC 9e-91 310.1 1.0 301.0 301.0 306 307 308 310 312 188 203 207 284 286 285 287.0 343 331 326 325 324 323 322 321 320 239 Dual specificity tyrosine-phosphorylation-regulated kinase 1A
CMGC DYRK1A DYR1A_HUMAN 3ANRD Q13627 134 479 763.0 HRM:1 Type1 Inactive DFGin 7.4388 14.887 BLAminus -126.79, 174.71 64.81, 86.52 -103.95, 22.81 283.21, 80.12 -67.2, -17.95 in-in in 8.734 Saltbr-in 2.9742 HRD-in -61.66, -39.95 66.39, -3.38 in-in-out SNCiio in-out ActLoopNT-in 2.8567 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oioi APE10-dihe-na -134.79, 162.98 APE9-dihe-na 75.68, 154.5 APE8-dihe-in -74.59, 142.8 APE8-rot-in 292.67 APE67-dihe-in -57.39, -25.31 -44.77, -54.21 APE12-dist-out 14.0346 APE11-dist-in 12.1447 APE10-dist-out 8.1653 APE9-dist-in 3.2451 None PTR321 PTR321 XRAY 2.6 0.232 0.264 D 368.0 341.0 5 25 25 0 [[159, 479]] 1.0 3anr CMGC_DYRK1A_HUMAN CMGC 9e-91 310.1 1.0 301.0 301.0 306 307 308 310 312 188 203 207 284 286 285 287.0 343 331 326 325 324 323 322 321 320 239 Dual specificity tyrosine-phosphorylation-regulated kinase 1A

PDB: 3ANR — CMGC DYR1A_HUMAN

Total number of chains: 4
Active chains: 1
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 4 100.0% 3ANRA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC DYRK1A DYR1A_HUMAN 3ANRA Q13627 134 481 763.0 HRM:1 Type1 Active DFGin 7.3952 14.8796 BLAminus -126.97, 175.57 62.29, 87.12 -103.96, 24.02 282.74, 80.66 -67.77, -18.58 in-in in 8.7055 Saltbr-in 2.9447 HRD-in -59.12, -43.08 70.29, -4.2 in-in-in SNCiii in-in ActLoopNT-in 2.803 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -124.86, 169.59 APE9-dihe-na 72.59, 157.32 APE8-dihe-in -74.37, 142.22 APE8-rot-in 294.27 APE67-dihe-in -55.49, -26.14 -45.5, -54.94 APE12-dist-in 13.813 APE11-dist-in 12.0606 APE10-dist-in 7.9549 APE9-dist-in 3.2535 None PTR321 PTR321 XRAY 2.6 0.232 0.264 A 368.0 343.0 5 25 25 0 [[159, 479]] 1.0 3anr Homo sapiens CMGC_DYRK1A_HUMAN CMGC 9e-91 310.1 1.0 301.0 301.0 306 307 308 310 312 188 203 207 284 286 285 287.0 343 331 326 325 324 323 322 321 320 239 Dual specificity tyrosine-phosphorylation-regulated kinase 1A
CMGC DYRK1A DYR1A_HUMAN 3ANRB Q13627 133 481 763.0 HRM:1 Type1 Inactive DFGin 7.4555 14.9313 BLAminus -127.37, 175.29 64.18, 86.03 -102.43, 22.55 283.14, 80.72 -64.64, -20.73 in-in in 8.7327 Saltbr-in 2.8661 HRD-in -58.01, -41.76 68.55, -4.63 in-in-out SNCiio in-out ActLoopNT-in 2.9937 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_iioi APE10-dihe-na -113.3, 162.51 APE9-dihe-na 75.38, 151.66 APE8-dihe-in -71.98, 142.21 APE8-rot-in 293.97 APE67-dihe-in -54.5, -26.35 -45.44, -54.76 APE12-dist-in 13.7489 APE11-dist-in 11.8941 APE10-dist-out 8.014 APE9-dist-in 3.315 None PTR321 PTR321 XRAY 2.6 0.232 0.264 B 368.0 343.0 6 25 25 0 [[159, 479]] 1.0 3anr Homo sapiens CMGC_DYRK1A_HUMAN CMGC 9e-91 310.1 1.0 301.0 301.0 306 307 308 310 312 188 203 207 284 286 285 287.0 343 331 326 325 324 323 322 321 320 239 Dual specificity tyrosine-phosphorylation-regulated kinase 1A
CMGC DYRK1A DYR1A_HUMAN 3ANRC Q13627 134 481 763.0 HRM:1 Type1 Inactive DFGin 7.3517 14.8245 BLAminus -127.39, 175.73 63.91, 86.99 -105.92, 24.64 282.96, 79.27 -68.52, -18.05 in-in in 8.7205 Saltbr-in 2.9637 HRD-in -60.25, -41.86 68.21, -2.43 in-in-out SNCiio in-out ActLoopNT-in 2.9578 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oioi APE10-dihe-na -115.38, 158.82 APE9-dihe-na 80.57, 155.21 APE8-dihe-in -73.66, 142.81 APE8-rot-in 291.66 APE67-dihe-in -55.43, -28.06 -45.81, -53.64 APE12-dist-out 14.2127 APE11-dist-in 12.1151 APE10-dist-out 8.2585 APE9-dist-in 3.3346 None PTR321 PTR321 XRAY 2.6 0.232 0.264 C 368.0 338.0 10 25 25 0 [[159, 479]] 1.0 3anr Homo sapiens CMGC_DYRK1A_HUMAN CMGC 9e-91 310.1 1.0 301.0 301.0 306 307 308 310 312 188 203 207 284 286 285 287.0 343 331 326 325 324 323 322 321 320 239 Dual specificity tyrosine-phosphorylation-regulated kinase 1A
CMGC DYRK1A DYR1A_HUMAN 3ANRD Q13627 134 479 763.0 HRM:1 Type1 Inactive DFGin 7.4388 14.887 BLAminus -126.79, 174.71 64.81, 86.52 -103.95, 22.81 283.21, 80.12 -67.2, -17.95 in-in in 8.734 Saltbr-in 2.9742 HRD-in -61.66, -39.95 66.39, -3.38 in-in-out SNCiio in-out ActLoopNT-in 2.8567 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_oioi APE10-dihe-na -134.79, 162.98 APE9-dihe-na 75.68, 154.5 APE8-dihe-in -74.59, 142.8 APE8-rot-in 292.67 APE67-dihe-in -57.39, -25.31 -44.77, -54.21 APE12-dist-out 14.0346 APE11-dist-in 12.1447 APE10-dist-out 8.1653 APE9-dist-in 3.2451 None PTR321 PTR321 XRAY 2.6 0.232 0.264 D 368.0 341.0 5 25 25 0 [[159, 479]] 1.0 3anr Homo sapiens CMGC_DYRK1A_HUMAN CMGC 9e-91 310.1 1.0 301.0 301.0 306 307 308 310 312 188 203 207 284 286 285 287.0 343 331 326 325 324 323 322 321 320 239 Dual specificity tyrosine-phosphorylation-regulated kinase 1A

PDB: 3ANR — CMGC DYR1A_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name