PDB: 2X7O — TKL TGFR1_HUMAN

Total number of chains: 5
Active chains: 4
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 5 100.0% 2X7OA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL TGFBR1 TGFR1_HUMAN 2X7OA P36897 171 500 503.0 ZOP:600 Type1 Active DFGin 6.8319 13.7743 BLAminus -128.16, 169.92 59.52, 88.44 -108.37, 28.14 289.28, 149.08 -69.29, -30.37 in-in in 8.0878 Saltbr-in 3.5322 HRD-in -65.4, -40.58 69.2, -25.74 in-in-in SNCiii in-in ActLoopNT-in 3.0569 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -130.88, 149.39 APE9-dihe-na 96.51, -171.18 APE8-dihe-in -74.29, 131.0 APE8-rot-in 315.1 APE67-dihe-in -64.94, -34.48 -61.98, -32.57 APE12-dist-in 11.8201 APE11-dist-in 11.797 APE10-dist-in 5.9727 APE9-dist-in 4.7389 None None None XRAY 3.7 0.267 0.273 A 342.0 330.0 0 32 32 0 [[205, 494]] 1.0 2x7o TKL_TGFBR1_HUMAN TKL 4.9e-85 291.2 3.0 266.0 264.0 350 351 352 354 356 232 245 249 330 332 331 333.0 400 382 377 376 375 374 373 372 371 281 TGF-beta receptor type-1
TKL TGFBR1 TGFR1_HUMAN 2X7OB P36897 171 500 503.0 ZOP:600 Type1 Inactive DFGin 6.8577 13.7456 BLAminus -128.22, 169.83 59.7, 88.26 -108.23, 28.26 289.27, 149.16 -69.33, -30.83 in-out in 8.1184 Saltbr-out 3.8328 HRD-in -65.55, -40.47 69.31, -25.99 out-in-in SNCoii in-in ActLoopNT-in 3.059 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -131.06, 149.04 APE9-dihe-na 97.27, -171.94 APE8-dihe-in -74.39, 131.11 APE8-rot-in 314.97 APE67-dihe-in -65.1, -35.09 -61.66, -32.49 APE12-dist-in 11.7932 APE11-dist-in 11.7932 APE10-dist-in 5.9674 APE9-dist-in 4.7272 None None None XRAY 3.7 0.267 0.273 B 342.0 330.0 0 32 32 0 [[205, 494]] 1.0 2x7o TKL_TGFBR1_HUMAN TKL 4.9e-85 291.2 3.0 266.0 264.0 350 351 352 354 356 232 245 249 330 332 331 333.0 400 382 377 376 375 374 373 372 371 281 TGF-beta receptor type-1
TKL TGFBR1 TGFR1_HUMAN 2X7OC P36897 171 500 503.0 ZOP:600 Type1.5_Back Active DFGin 6.8533 13.7407 BLAminus -128.05, 170.08 59.35, 88.53 -108.53, 28.35 289.5, 149.12 -69.05, -31.39 in-in in 8.0731 Saltbr-in 3.511 HRD-in -65.39, -40.6 69.36, -25.98 in-in-in SNCiii in-in ActLoopNT-in 3.0597 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -130.94, 148.96 APE9-dihe-na 97.31, -171.76 APE8-dihe-in -74.42, 131.23 APE8-rot-in 314.85 APE67-dihe-in -65.62, -33.63 -61.56, -33.26 APE12-dist-in 11.7848 APE11-dist-in 11.7925 APE10-dist-in 5.9672 APE9-dist-in 4.7319 None None None XRAY 3.7 0.267 0.273 C 342.0 330.0 0 32 32 0 [[205, 494]] 1.0 2x7o TKL_TGFBR1_HUMAN TKL 4.9e-85 291.2 3.0 266.0 264.0 350 351 352 354 356 232 245 249 330 332 331 333.0 400 382 377 376 375 374 373 372 371 281 TGF-beta receptor type-1
TKL TGFBR1 TGFR1_HUMAN 2X7OD P36897 171 500 503.0 ZOP:600 Type1.5_Back Active DFGin 6.8515 13.7705 BLAminus -128.04, 169.94 59.4, 88.47 -108.43, 28.21 289.11, 149.16 -69.32, -30.88 in-in in 8.0909 Saltbr-in 3.5347 HRD-in -65.64, -40.65 69.2, -26.08 in-in-in SNCiii in-in ActLoopNT-in 3.0568 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -130.87, 149.08 APE9-dihe-na 96.88, -171.59 APE8-dihe-in -74.3, 131.16 APE8-rot-in 314.89 APE67-dihe-in -64.63, -35.86 -61.66, -32.82 APE12-dist-in 11.7959 APE11-dist-in 11.8009 APE10-dist-in 5.9723 APE9-dist-in 4.735 None None None XRAY 3.7 0.267 0.273 D 342.0 330.0 0 32 32 0 [[205, 494]] 1.0 2x7o TKL_TGFBR1_HUMAN TKL 4.9e-85 291.2 3.0 266.0 264.0 350 351 352 354 356 232 245 249 330 332 331 333.0 400 382 377 376 375 374 373 372 371 281 TGF-beta receptor type-1
TKL TGFBR1 TGFR1_HUMAN 2X7OE P36897 171 500 503.0 ZOP:600 Type1.5_Back Active DFGin 6.8561 13.7287 BLAminus -128.08, 169.89 59.79, 88.24 -108.3, 28.24 289.35, 149.2 -69.25, -30.86 in-in in 8.09 Saltbr-in 3.5516 HRD-in -65.48, -40.48 69.3, -25.97 in-in-in SNCiii in-in ActLoopNT-in 3.0589 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -126.31, 151.21 APE9-dihe-na 97.11, -171.6 APE8-dihe-in -74.4, 131.12 APE8-rot-in 315.09 APE67-dihe-in -65.13, -34.5 -61.63, -32.52 APE12-dist-in 11.7792 APE11-dist-in 11.735 APE10-dist-in 5.956 APE9-dist-in 4.7312 None None None XRAY 3.7 0.267 0.273 E 342.0 330.0 0 32 32 0 [[205, 494]] 1.0 2x7o TKL_TGFBR1_HUMAN TKL 4.9e-85 291.2 3.0 266.0 264.0 350 351 352 354 356 232 245 249 330 332 331 333.0 400 382 377 376 375 374 373 372 371 281 TGF-beta receptor type-1

PDB: 2X7O — TKL TGFR1_HUMAN

Total number of chains: 5
Active chains: 4
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 5 100.0% 2X7OA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL TGFBR1 TGFR1_HUMAN 2X7OA P36897 171 500 503.0 ZOP:600 Type1 Active DFGin 6.8319 13.7743 BLAminus -128.16, 169.92 59.52, 88.44 -108.37, 28.14 289.28, 149.08 -69.29, -30.37 in-in in 8.0878 Saltbr-in 3.5322 HRD-in -65.4, -40.58 69.2, -25.74 in-in-in SNCiii in-in ActLoopNT-in 3.0569 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -130.88, 149.39 APE9-dihe-na 96.51, -171.18 APE8-dihe-in -74.29, 131.0 APE8-rot-in 315.1 APE67-dihe-in -64.94, -34.48 -61.98, -32.57 APE12-dist-in 11.8201 APE11-dist-in 11.797 APE10-dist-in 5.9727 APE9-dist-in 4.7389 None None None XRAY 3.7 0.267 0.273 A 342.0 330.0 0 32 32 0 [[205, 494]] 1.0 2x7o Homo sapiens TKL_TGFBR1_HUMAN TKL 4.9e-85 291.2 3.0 266.0 264.0 350 351 352 354 356 232 245 249 330 332 331 333.0 400 382 377 376 375 374 373 372 371 281 TGF-beta receptor type-1
TKL TGFBR1 TGFR1_HUMAN 2X7OB P36897 171 500 503.0 ZOP:600 Type1 Inactive DFGin 6.8577 13.7456 BLAminus -128.22, 169.83 59.7, 88.26 -108.23, 28.26 289.27, 149.16 -69.33, -30.83 in-out in 8.1184 Saltbr-out 3.8328 HRD-in -65.55, -40.47 69.31, -25.99 out-in-in SNCoii in-in ActLoopNT-in 3.059 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -131.06, 149.04 APE9-dihe-na 97.27, -171.94 APE8-dihe-in -74.39, 131.11 APE8-rot-in 314.97 APE67-dihe-in -65.1, -35.09 -61.66, -32.49 APE12-dist-in 11.7932 APE11-dist-in 11.7932 APE10-dist-in 5.9674 APE9-dist-in 4.7272 None None None XRAY 3.7 0.267 0.273 B 342.0 330.0 0 32 32 0 [[205, 494]] 1.0 2x7o Homo sapiens TKL_TGFBR1_HUMAN TKL 4.9e-85 291.2 3.0 266.0 264.0 350 351 352 354 356 232 245 249 330 332 331 333.0 400 382 377 376 375 374 373 372 371 281 TGF-beta receptor type-1
TKL TGFBR1 TGFR1_HUMAN 2X7OC P36897 171 500 503.0 ZOP:600 Type1.5_Back Active DFGin 6.8533 13.7407 BLAminus -128.05, 170.08 59.35, 88.53 -108.53, 28.35 289.5, 149.12 -69.05, -31.39 in-in in 8.0731 Saltbr-in 3.511 HRD-in -65.39, -40.6 69.36, -25.98 in-in-in SNCiii in-in ActLoopNT-in 3.0597 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -130.94, 148.96 APE9-dihe-na 97.31, -171.76 APE8-dihe-in -74.42, 131.23 APE8-rot-in 314.85 APE67-dihe-in -65.62, -33.63 -61.56, -33.26 APE12-dist-in 11.7848 APE11-dist-in 11.7925 APE10-dist-in 5.9672 APE9-dist-in 4.7319 None None None XRAY 3.7 0.267 0.273 C 342.0 330.0 0 32 32 0 [[205, 494]] 1.0 2x7o Homo sapiens TKL_TGFBR1_HUMAN TKL 4.9e-85 291.2 3.0 266.0 264.0 350 351 352 354 356 232 245 249 330 332 331 333.0 400 382 377 376 375 374 373 372 371 281 TGF-beta receptor type-1
TKL TGFBR1 TGFR1_HUMAN 2X7OD P36897 171 500 503.0 ZOP:600 Type1.5_Back Active DFGin 6.8515 13.7705 BLAminus -128.04, 169.94 59.4, 88.47 -108.43, 28.21 289.11, 149.16 -69.32, -30.88 in-in in 8.0909 Saltbr-in 3.5347 HRD-in -65.64, -40.65 69.2, -26.08 in-in-in SNCiii in-in ActLoopNT-in 3.0568 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -130.87, 149.08 APE9-dihe-na 96.88, -171.59 APE8-dihe-in -74.3, 131.16 APE8-rot-in 314.89 APE67-dihe-in -64.63, -35.86 -61.66, -32.82 APE12-dist-in 11.7959 APE11-dist-in 11.8009 APE10-dist-in 5.9723 APE9-dist-in 4.735 None None None XRAY 3.7 0.267 0.273 D 342.0 330.0 0 32 32 0 [[205, 494]] 1.0 2x7o Homo sapiens TKL_TGFBR1_HUMAN TKL 4.9e-85 291.2 3.0 266.0 264.0 350 351 352 354 356 232 245 249 330 332 331 333.0 400 382 377 376 375 374 373 372 371 281 TGF-beta receptor type-1
TKL TGFBR1 TGFR1_HUMAN 2X7OE P36897 171 500 503.0 ZOP:600 Type1.5_Back Active DFGin 6.8561 13.7287 BLAminus -128.08, 169.89 59.79, 88.24 -108.3, 28.24 289.35, 149.2 -69.25, -30.86 in-in in 8.09 Saltbr-in 3.5516 HRD-in -65.48, -40.48 69.3, -25.97 in-in-in SNCiii in-in ActLoopNT-in 3.0589 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -126.31, 151.21 APE9-dihe-na 97.11, -171.6 APE8-dihe-in -74.4, 131.12 APE8-rot-in 315.09 APE67-dihe-in -65.13, -34.5 -61.63, -32.52 APE12-dist-in 11.7792 APE11-dist-in 11.735 APE10-dist-in 5.956 APE9-dist-in 4.7312 None None None XRAY 3.7 0.267 0.273 E 342.0 330.0 0 32 32 0 [[205, 494]] 1.0 2x7o Homo sapiens TKL_TGFBR1_HUMAN TKL 4.9e-85 291.2 3.0 266.0 264.0 350 351 352 354 356 232 245 249 330 332 331 333.0 400 382 377 376 375 374 373 372 371 281 TGF-beta receptor type-1

PDB: 2X7O — TKL TGFR1_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name