| Group | Gene | SwissprotID | PDB | UniprotID | First_obs_res | Last_obs_res | Length_Unp | Ligand | Ligand_type | Activity_label | Spatial_label | Phe_Glu4_dis | Phe_Lys_dis | Dihedral_label | XDFG φ,ψ |
DFG-Asp φ,ψ |
DFG-Phe φ,ψ |
DFG-Phe χ1,χ2 |
DFG-Gly φ,ψ |
ChelixSaltbr_label | Chelix_label | Lys_Glu_dis | Saltbr_label | LysNZ_GluOE_dis | HRD_label | His φ,ψ | Arg φ,ψ | SNC_label | SNCpymol_label | ActLoop_label | ActLoopNT_label | DFG6_XHRD_dis | ActLoopCT_label | APEtype | APEdihe_label | APEdist_label | APE10_dihe_label | APE10 φ,ψ | APE9_dihe_label | APE9 φ,ψ | APE8_dihe_label | APE8 φ,ψ | APE8_rotamer_label | APE8 χ1 | APE67_label | APE6 φ,ψ | APE7 φ,ψ | APE12_dist_label | APE12_DFG4_dis | APE11_dist_label | APE11_DFG4_dis | APE10_dist_label | APE10_DFG4_dis | APE9_dist_label | APE9_Arg_dis | Chain_mut | Chain_phos | Modified_aa | Method | Resolution | Rvalue | FreeRvalue | Chain_id | ChainLen | Ordered_residues | DomainBreak | ActLoopLength | ActLoopResolvedResidues | ActLoopDisorderedResidues | Kinase_domains_Unp | N_Kinase_domains_Unp | pdb | Kincore_name | hmm | Evalue | Score | hmmbeg | hmmend | hmmlen | XDFGnum | DFGnum | PHEnum | DFG4num | DFG6num | LYSnum | GLUnum | GLU4num | XHRDnum | ARGnum | HRDnum | HRDaspnum | aFaspnum | APEnum | APE6num | APE7num | APE8num | APE9num | APE10num | APE11num | APE12num | Hinge1num | Protein_name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| TYR | ERBB4 | ERBB4_HUMAN | 2R4BA | Q15303 | 694 | 991 | 1308.0 | GW7:1 | Type1.5_Back | Inactive | DFGin | 4.8884 | 13.7643 | BLBplus | -131.45, 171.83 | 72.48, 18.96 | -72.29, 139.7 | 46.29, 78.43 | 96.99, -38.5 | out-out | out | 12.4712 | Saltbr-out | 12.4472 | HRD-in | -72.41, -53.35 | 83.43, -17.46 | out-out-out | SNCooo | out-out | ActLoopNT-out | 6.626 | ActLoopCT-out | TYR | APEdihe_oiiai | APEdist_aaai | APE10-dihe-out | -96.99, -22.63 | APE9-dihe-in | -79.79, 147.87 | APE8-dihe-in | -66.33, 125.88 | APE8-rot-na | 22.44 | APE67-dihe-in | -72.84, -10.87 | -47.99, -38.08 | APE12-dist-na | 16.1637 | APE11-dist-na | 12.7639 | APE10-dist-na | 9.1884 | APE9-dist-in | 5.4581 | None | None | None | XRAY | 2.4 | 0.209 | 0.263 | A | 321.0 | 292.0 | 6 | 30 | 30 | 0 | [[718, 976]] | 1.0 | 2r4b | TYR_ERBB4_HUMAN | TYR | 1.1e-91 | 312.8 | 2.0 | 259.0 | 258.0 | 860 | 861 | 862 | 864 | 866 | 751 | 768 | 772 | 840 | 842 | 841 | 843.0 | 902 | 890 | 885 | 884 | 883 | 882 | 881 | 880 | 879 | 797 | Receptor tyrosine-protein kinase erbB-4 |
| TYR | ERBB4 | ERBB4_HUMAN | 2R4BB | Q15303 | 694 | 991 | 1308.0 | GW7:1 | Type1.5_Back | Inactive | DFGin | 4.9841 | 13.6997 | BLBplus | -129.8, 173.21 | 73.77, 11.79 | -69.91, 143.8 | 45.64, 81.74 | 93.59, -37.44 | out-out | out | 12.5298 | Saltbr-out | 12.2339 | HRD-in | -79.37, -52.03 | 82.87, -19.74 | out-out-out | SNCooo | out-out | ActLoopNT-out | 6.5003 | ActLoopCT-out | TYR | APEdihe_oiiai | APEdist_aaai | APE10-dihe-out | -100.32, -24.68 | APE9-dihe-in | -77.32, 145.71 | APE8-dihe-in | -64.77, 128.36 | APE8-rot-na | 23.01 | APE67-dihe-in | -77.58, -10.73 | -52.3, -32.59 | APE12-dist-na | 16.1561 | APE11-dist-na | 12.8936 | APE10-dist-na | 9.2532 | APE9-dist-in | 5.4477 | None | None | None | XRAY | 2.4 | 0.209 | 0.263 | B | 321.0 | 291.0 | 7 | 30 | 30 | 0 | [[718, 976]] | 1.0 | 2r4b | TYR_ERBB4_HUMAN | TYR | 1.1e-91 | 312.8 | 2.0 | 259.0 | 258.0 | 860 | 861 | 862 | 864 | 866 | 751 | 768 | 772 | 840 | 842 | 841 | 843.0 | 902 | 890 | 885 | 884 | 883 | 882 | 881 | 880 | 879 | 797 | Receptor tyrosine-protein kinase erbB-4 |
| Group | Gene | SwissprotID | PDB | UniprotID | First_obs_res | Last_obs_res | Length_Unp | Ligand | Ligand_type | Activity_label | Spatial_label | Phe_Glu4_dis | Phe_Lys_dis | Dihedral_label | XDFG φ,ψ |
DFG-Asp φ,ψ |
DFG-Phe φ,ψ |
DFG-Phe χ1,χ2 |
DFG-Gly φ,ψ |
ChelixSaltbr_label | Chelix_label | Lys_Glu_dis | Saltbr_label | LysNZ_GluOE_dis | HRD_label | His φ,ψ | Arg φ,ψ | SNC_label | SNCpymol_label | ActLoop_label | ActLoopNT_label | DFG6_XHRD_dis | ActLoopCT_label | APEtype | APEdihe_label | APEdist_label | APE10_dihe_label | APE10 φ,ψ | APE9_dihe_label | APE9 φ,ψ | APE8_dihe_label | APE8 φ,ψ | APE8_rotamer_label | APE8 χ1 | APE67_label | APE6 φ,ψ | APE7 φ,ψ | APE12_dist_label | APE12_DFG4_dis | APE11_dist_label | APE11_DFG4_dis | APE10_dist_label | APE10_DFG4_dis | APE9_dist_label | APE9_Arg_dis | Chain_mut | Chain_phos | Modified_aa | Method | Resolution | Rvalue | FreeRvalue | Chain_id | ChainLen | Ordered_residues | DomainBreak | ActLoopLength | ActLoopResolvedResidues | ActLoopDisorderedResidues | Kinase_domains_Unp | N_Kinase_domains_Unp | pdb | Species | Kincore_name | hmm | Evalue | Score | hmmbeg | hmmend | hmmlen | XDFGnum | DFGnum | PHEnum | DFG4num | DFG6num | LYSnum | GLUnum | GLU4num | XHRDnum | ARGnum | HRDnum | HRDaspnum | aFaspnum | APEnum | APE6num | APE7num | APE8num | APE9num | APE10num | APE11num | APE12num | Hinge1num | Protein_name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| TYR | ERBB4 | ERBB4_HUMAN | 2R4BA | Q15303 | 694 | 991 | 1308.0 | GW7:1 | Type1.5_Back | Inactive | DFGin | 4.8884 | 13.7643 | BLBplus | -131.45, 171.83 | 72.48, 18.96 | -72.29, 139.7 | 46.29, 78.43 | 96.99, -38.5 | out-out | out | 12.4712 | Saltbr-out | 12.4472 | HRD-in | -72.41, -53.35 | 83.43, -17.46 | out-out-out | SNCooo | out-out | ActLoopNT-out | 6.626 | ActLoopCT-out | TYR | APEdihe_oiiai | APEdist_aaai | APE10-dihe-out | -96.99, -22.63 | APE9-dihe-in | -79.79, 147.87 | APE8-dihe-in | -66.33, 125.88 | APE8-rot-na | 22.44 | APE67-dihe-in | -72.84, -10.87 | -47.99, -38.08 | APE12-dist-na | 16.1637 | APE11-dist-na | 12.7639 | APE10-dist-na | 9.1884 | APE9-dist-in | 5.4581 | None | None | None | XRAY | 2.4 | 0.209 | 0.263 | A | 321.0 | 292.0 | 6 | 30 | 30 | 0 | [[718, 976]] | 1.0 | 2r4b | Homo sapiens | TYR_ERBB4_HUMAN | TYR | 1.1e-91 | 312.8 | 2.0 | 259.0 | 258.0 | 860 | 861 | 862 | 864 | 866 | 751 | 768 | 772 | 840 | 842 | 841 | 843.0 | 902 | 890 | 885 | 884 | 883 | 882 | 881 | 880 | 879 | 797 | Receptor tyrosine-protein kinase erbB-4 |
| TYR | ERBB4 | ERBB4_HUMAN | 2R4BB | Q15303 | 694 | 991 | 1308.0 | GW7:1 | Type1.5_Back | Inactive | DFGin | 4.9841 | 13.6997 | BLBplus | -129.8, 173.21 | 73.77, 11.79 | -69.91, 143.8 | 45.64, 81.74 | 93.59, -37.44 | out-out | out | 12.5298 | Saltbr-out | 12.2339 | HRD-in | -79.37, -52.03 | 82.87, -19.74 | out-out-out | SNCooo | out-out | ActLoopNT-out | 6.5003 | ActLoopCT-out | TYR | APEdihe_oiiai | APEdist_aaai | APE10-dihe-out | -100.32, -24.68 | APE9-dihe-in | -77.32, 145.71 | APE8-dihe-in | -64.77, 128.36 | APE8-rot-na | 23.01 | APE67-dihe-in | -77.58, -10.73 | -52.3, -32.59 | APE12-dist-na | 16.1561 | APE11-dist-na | 12.8936 | APE10-dist-na | 9.2532 | APE9-dist-in | 5.4477 | None | None | None | XRAY | 2.4 | 0.209 | 0.263 | B | 321.0 | 291.0 | 7 | 30 | 30 | 0 | [[718, 976]] | 1.0 | 2r4b | Homo sapiens | TYR_ERBB4_HUMAN | TYR | 1.1e-91 | 312.8 | 2.0 | 259.0 | 258.0 | 860 | 861 | 862 | 864 | 866 | 751 | 768 | 772 | 840 | 842 | 841 | 843.0 | 902 | 890 | 885 | 884 | 883 | 882 | 881 | 880 | 879 | 797 | Receptor tyrosine-protein kinase erbB-4 |
| Spatial label | Dihedral label | Number of Chains | Percent | Representative |
|---|
| Group | Gene | SwissprotID | PDB | UniprotID | First_obs_res | Last_obs_res | Length_Unp | Ligand | Ligand_type | Activity_label | Spatial_label | Phe_Glu4_dis | Phe_Lys_dis | Dihedral_label | XDFG φ,ψ |
DFG-Asp φ,ψ |
DFG-Phe φ,ψ |
DFG-Phe χ1,χ2 |
DFG-Gly φ,ψ |
ChelixSaltbr_label | Chelix_label | Lys_Glu_dis | Saltbr_label | LysNZ_GluOE_dis | HRD_label | His φ,ψ | Arg φ,ψ | SNC_label | SNCpymol_label | ActLoop_label | ActLoopNT_label | DFG6_XHRD_dis | ActLoopCT_label | APEtype | APEdihe_label | APEdist_label | APE10_dihe_label | APE10 φ,ψ | APE9_dihe_label | APE9 φ,ψ | APE8_dihe_label | APE8 φ,ψ | APE8_rotamer_label | APE8 χ1 | APE67_label | APE6 φ,ψ | APE7 φ,ψ | APE12_dist_label | APE12_DFG4_dis | APE11_dist_label | APE11_DFG4_dis | APE10_dist_label | APE10_DFG4_dis | APE9_dist_label | APE9_Arg_dis | Chain_mut | Chain_phos | Modified_aa | Method | Resolution | Rvalue | FreeRvalue | Chain_id | ChainLen | Ordered_residues | DomainBreak | ActLoopLength | ActLoopResolvedResidues | ActLoopDisorderedResidues | Kinase_domains_Unp | N_Kinase_domains_Unp | pdb | Species | Kincore_name | hmm | Evalue | Score | hmmbeg | hmmend | hmmlen | XDFGnum | DFGnum | PHEnum | DFG4num | DFG6num | LYSnum | GLUnum | GLU4num | XHRDnum | ARGnum | HRDnum | HRDaspnum | aFaspnum | APEnum | APE6num | APE7num | APE8num | APE9num | APE10num | APE11num | APE12num | Hinge1num | Protein_name |
|---|