PDB: 2ONL — 2 kinases

Total number of chains: 4
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 50.0% 2ONLC
DFGin BLBminus 2 50.0% 2ONLB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CAMK MAPKAPK2 MAPK2_HUMAN 2ONLC P49137 46 393 400.0 No_ligand No_ligand Inactive DFGin 5.3716 13.8775 BLAminus -144.71, 177.23 57.74, 79.95 -93.42, 20.24 283.94, 44.28 -42.17, -30.27 out-out out 10.4822 Saltbr-out 5.1589 HRD-in -63.93, -50.35 64.99, 1.87 out-in-out SNCoio in-out ActLoopNT-in 2.6783 ActLoopCT-out nonTYR APEdihe_aaoio APEdist_oooo APE10-dihe-na -145.05, 148.13 APE9-dihe-na -79.09, -172.22 APE8-dihe-out -151.58, -163.46 APE8-rot-in 293.27 APE67-dihe-out -61.73, 102.69 -87.71, -35.23 APE12-dist-out 31.6639 APE11-dist-out 35.028 APE10-dist-out 35.9403 APE9-dist-out 30.1458 None None None XRAY 4.0 0.315 0.331 C 406.0 317.0 31 27 27 0 [[63, 325]] 1.0 2onl CAMK_MAPKAPK2_HUMAN CAMK 7e-80 274.2 3.0 256.0 254.0 206 207 208 210 212 93 104 108 183 185 184 186.0 245 233 228 227 226 225 224 223 222 139 MAP kinase-activated protein kinase 2
CAMK MAPKAPK2 MAPK2_HUMAN 2ONLD P49137 46 393 400.0 No_ligand No_ligand Inactive DFGin 4.2247 13.8481 BLAminus -137.37, 177.77 67.14, 69.15 -84.34, 79.92 286.72, 38.57 -108.36, -19.15 out-out out 11.0046 Saltbr-out 7.4082 HRD-out -59.16, 114.42 -89.49, -17.7 out-in-out SNCoio in-out ActLoopNT-in 2.5955 ActLoopCT-out nonTYR APEdihe_aaooo APEdist_oooo APE10-dihe-na -152.0, 123.99 APE9-dihe-na -67.05, 173.86 APE8-dihe-out -109.94, -76.7 APE8-rot-out 147.79 APE67-dihe-out -164.84, -165.18 -122.96, 14.75 APE12-dist-out 31.0185 APE11-dist-out 34.1961 APE10-dist-out 36.3708 APE9-dist-out 29.9024 None None None XRAY 4.0 0.315 0.331 D 406.0 313.0 35 27 27 0 [[63, 325]] 1.0 2onl CAMK_MAPKAPK2_HUMAN CAMK 7e-80 274.2 3.0 256.0 254.0 206 207 208 210 212 93 104 108 183 185 184 186.0 245 233 228 227 226 225 224 223 222 139 MAP kinase-activated protein kinase 2
CMGC MAPK14 MK14_HUMAN 2ONLA Q16539 4 352 360.0 No_ligand No_ligand Inactive DFGin 7.2877 16.1056 BLBminus -139.8, -177.93 43.34, 77.4 -75.22, 146.44 290.54, 41.49 -62.95, 116.48 in-in in 9.4516 Saltbr-in 2.6513 HRD-in -52.0, -56.17 74.39, -2.78 in-out-none SNCion out-none ActLoopNT-out 9.1471 ActLoopCT-none nonTYR APEdihe_aanni APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 49.36 APE8-rot-none 999.0 APE67-dihe-in -86.46, -33.32 -110.87, 9.1 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 None None None XRAY 4.0 0.315 0.331 A 366.0 338.0 11 25 14 11 [[24, 308]] 1.0 2onl CMGC_MAPK14_HUMAN CMGC 6.2e-85 291.1 1.0 301.0 301.0 167 168 169 171 173 53 71 75 147 149 148 150.0 205 192 187 186 185 184 183 182 181 107 Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 2ONLB Q16539 4 352 360.0 No_ligand No_ligand Inactive DFGin 7.3212 16.1634 BLBminus -141.81, -179.23 45.19, 76.7 -75.31, 145.49 288.03, 42.26 -62.52, 115.05 in-in in 9.4911 Saltbr-in 2.8294 HRD-in -52.05, -57.26 76.3, -1.57 in-out-out SNCioo out-out ActLoopNT-out 9.1161 ActLoopCT-out nonTYR APEdihe_aaoni APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, -126.14 APE8-dihe-out -128.48, 30.34 APE8-rot-none 999.0 APE67-dihe-in -39.69, -33.92 -99.79, -26.07 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 13.1744 None None None XRAY 4.0 0.315 0.331 B 366.0 339.0 10 25 15 10 [[24, 308]] 1.0 2onl CMGC_MAPK14_HUMAN CMGC 6.2e-85 291.1 1.0 301.0 301.0 167 168 169 171 173 53 71 75 147 149 148 150.0 205 192 187 186 185 184 183 182 181 107 Mitogen-activated protein kinase 14

PDB: 2ONL — 2 kinases

Total number of chains: 4
Active chains: 0
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 50.0% 2ONLC
DFGin BLBminus 2 50.0% 2ONLB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CAMK MAPKAPK2 MAPK2_HUMAN 2ONLC P49137 46 393 400.0 No_ligand No_ligand Inactive DFGin 5.3716 13.8775 BLAminus -144.71, 177.23 57.74, 79.95 -93.42, 20.24 283.94, 44.28 -42.17, -30.27 out-out out 10.4822 Saltbr-out 5.1589 HRD-in -63.93, -50.35 64.99, 1.87 out-in-out SNCoio in-out ActLoopNT-in 2.6783 ActLoopCT-out nonTYR APEdihe_aaoio APEdist_oooo APE10-dihe-na -145.05, 148.13 APE9-dihe-na -79.09, -172.22 APE8-dihe-out -151.58, -163.46 APE8-rot-in 293.27 APE67-dihe-out -61.73, 102.69 -87.71, -35.23 APE12-dist-out 31.6639 APE11-dist-out 35.028 APE10-dist-out 35.9403 APE9-dist-out 30.1458 None None None XRAY 4.0 0.315 0.331 C 406.0 317.0 31 27 27 0 [[63, 325]] 1.0 2onl Homo sapiens CAMK_MAPKAPK2_HUMAN CAMK 7e-80 274.2 3.0 256.0 254.0 206 207 208 210 212 93 104 108 183 185 184 186.0 245 233 228 227 226 225 224 223 222 139 MAP kinase-activated protein kinase 2
CAMK MAPKAPK2 MAPK2_HUMAN 2ONLD P49137 46 393 400.0 No_ligand No_ligand Inactive DFGin 4.2247 13.8481 BLAminus -137.37, 177.77 67.14, 69.15 -84.34, 79.92 286.72, 38.57 -108.36, -19.15 out-out out 11.0046 Saltbr-out 7.4082 HRD-out -59.16, 114.42 -89.49, -17.7 out-in-out SNCoio in-out ActLoopNT-in 2.5955 ActLoopCT-out nonTYR APEdihe_aaooo APEdist_oooo APE10-dihe-na -152.0, 123.99 APE9-dihe-na -67.05, 173.86 APE8-dihe-out -109.94, -76.7 APE8-rot-out 147.79 APE67-dihe-out -164.84, -165.18 -122.96, 14.75 APE12-dist-out 31.0185 APE11-dist-out 34.1961 APE10-dist-out 36.3708 APE9-dist-out 29.9024 None None None XRAY 4.0 0.315 0.331 D 406.0 313.0 35 27 27 0 [[63, 325]] 1.0 2onl Homo sapiens CAMK_MAPKAPK2_HUMAN CAMK 7e-80 274.2 3.0 256.0 254.0 206 207 208 210 212 93 104 108 183 185 184 186.0 245 233 228 227 226 225 224 223 222 139 MAP kinase-activated protein kinase 2
CMGC MAPK14 MK14_HUMAN 2ONLA Q16539 4 352 360.0 No_ligand No_ligand Inactive DFGin 7.2877 16.1056 BLBminus -139.8, -177.93 43.34, 77.4 -75.22, 146.44 290.54, 41.49 -62.95, 116.48 in-in in 9.4516 Saltbr-in 2.6513 HRD-in -52.0, -56.17 74.39, -2.78 in-out-none SNCion out-none ActLoopNT-out 9.1471 ActLoopCT-none nonTYR APEdihe_aanni APEdist_nnnn APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, 999.0 APE8-dihe-none 999.0, 49.36 APE8-rot-none 999.0 APE67-dihe-in -86.46, -33.32 -110.87, 9.1 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-none 999.0 None None None XRAY 4.0 0.315 0.331 A 366.0 338.0 11 25 14 11 [[24, 308]] 1.0 2onl Homo sapiens CMGC_MAPK14_HUMAN CMGC 6.2e-85 291.1 1.0 301.0 301.0 167 168 169 171 173 53 71 75 147 149 148 150.0 205 192 187 186 185 184 183 182 181 107 Mitogen-activated protein kinase 14
CMGC MAPK14 MK14_HUMAN 2ONLB Q16539 4 352 360.0 No_ligand No_ligand Inactive DFGin 7.3212 16.1634 BLBminus -141.81, -179.23 45.19, 76.7 -75.31, 145.49 288.03, 42.26 -62.52, 115.05 in-in in 9.4911 Saltbr-in 2.8294 HRD-in -52.05, -57.26 76.3, -1.57 in-out-out SNCioo out-out ActLoopNT-out 9.1161 ActLoopCT-out nonTYR APEdihe_aaoni APEdist_nnno APE10-dihe-na 999.0, 999.0 APE9-dihe-na 999.0, -126.14 APE8-dihe-out -128.48, 30.34 APE8-rot-none 999.0 APE67-dihe-in -39.69, -33.92 -99.79, -26.07 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-none 999.0 APE9-dist-out 13.1744 None None None XRAY 4.0 0.315 0.331 B 366.0 339.0 10 25 15 10 [[24, 308]] 1.0 2onl Homo sapiens CMGC_MAPK14_HUMAN CMGC 6.2e-85 291.1 1.0 301.0 301.0 167 168 169 171 173 53 71 75 147 149 148 150.0 205 192 187 186 185 184 183 182 181 107 Mitogen-activated protein kinase 14

PDB: 2ONL — 2 kinases

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name