PDB: 2O8Y — TKL IRAK4_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 2O8YA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL IRAK4 IRAK4_HUMAN 2O8YA Q9NWZ3 165 459 460.0 No_ligand No_ligand Inactive DFGin 6.8416 14.5911 BLAminus -132.39, 177.22 66.07, 84.3 -105.54, 20.57 305.43, 80.78 -65.44, -21.01 in-out in 9.2203 Saltbr-out 5.2604 HRD-in -67.22, -51.44 76.47, -5.87 out-in-in SNCoii in-in ActLoopNT-in 2.6453 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -134.99, 161.49 APE9-dihe-na 137.04, -166.6 APE8-dihe-in -112.18, 123.59 APE8-rot-in 299.28 APE67-dihe-in -59.66, -14.58 -45.01, -56.42 APE12-dist-in 10.1061 APE11-dist-in 11.7981 APE10-dist-in 6.4734 APE9-dist-in 3.6984 None TPO342,TPO345 MSE192,MSE237,MSE265,MSE287,TPO342,MSE344,TPO345,MSE355,MSE418,MSE429,MSE457 XRAY 2.4 0.246 0.289 A 298.0 280.0 15 30 25 5 [[183, 456]] 1.0 2o8y TKL_IRAK4_HUMAN TKL 3.9e-84 288.3 5.0 266.0 262.0 328 329 330 332 334 213 233 237 308 310 309 311.0 369 358 353 352 351 350 349 348 347 263 Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 2O8YB Q9NWZ3 165 459 460.0 No_ligand No_ligand Inactive DFGin 6.9821 14.8022 BLAminus -133.86, -178.63 62.43, 89.29 -111.36, 23.7 306.19, 76.11 -69.27, -12.74 in-out in 8.717 Saltbr-out 4.0968 HRD-in -66.08, -48.44 73.53, 0.66 out-in-in SNCoii in-in ActLoopNT-in 2.8454 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -121.84, 167.68 APE9-dihe-na 128.52, -172.33 APE8-dihe-in -109.54, 116.11 APE8-rot-in 303.67 APE67-dihe-in -57.63, -18.12 -43.35, -51.59 APE12-dist-in 10.3467 APE11-dist-in 11.6456 APE10-dist-in 6.2992 APE9-dist-in 3.8249 None TPO342,TPO345 MSE192,MSE237,MSE265,MSE287,TPO342,MSE344,TPO345,MSE355,MSE418,MSE429,MSE457 XRAY 2.4 0.246 0.289 B 298.0 277.0 18 30 26 4 [[183, 456]] 1.0 2o8y TKL_IRAK4_HUMAN TKL 3.9e-84 288.3 5.0 266.0 262.0 328 329 330 332 334 213 233 237 308 310 309 311.0 369 358 353 352 351 350 349 348 347 263 Interleukin-1 receptor-associated kinase 4

PDB: 2O8Y — TKL IRAK4_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 2O8YA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL IRAK4 IRAK4_HUMAN 2O8YA Q9NWZ3 165 459 460.0 No_ligand No_ligand Inactive DFGin 6.8416 14.5911 BLAminus -132.39, 177.22 66.07, 84.3 -105.54, 20.57 305.43, 80.78 -65.44, -21.01 in-out in 9.2203 Saltbr-out 5.2604 HRD-in -67.22, -51.44 76.47, -5.87 out-in-in SNCoii in-in ActLoopNT-in 2.6453 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -134.99, 161.49 APE9-dihe-na 137.04, -166.6 APE8-dihe-in -112.18, 123.59 APE8-rot-in 299.28 APE67-dihe-in -59.66, -14.58 -45.01, -56.42 APE12-dist-in 10.1061 APE11-dist-in 11.7981 APE10-dist-in 6.4734 APE9-dist-in 3.6984 None TPO342,TPO345 MSE192,MSE237,MSE265,MSE287,TPO342,MSE344,TPO345,MSE355,MSE418,MSE429,MSE457 XRAY 2.4 0.246 0.289 A 298.0 280.0 15 30 25 5 [[183, 456]] 1.0 2o8y Homo sapiens TKL_IRAK4_HUMAN TKL 3.9e-84 288.3 5.0 266.0 262.0 328 329 330 332 334 213 233 237 308 310 309 311.0 369 358 353 352 351 350 349 348 347 263 Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 2O8YB Q9NWZ3 165 459 460.0 No_ligand No_ligand Inactive DFGin 6.9821 14.8022 BLAminus -133.86, -178.63 62.43, 89.29 -111.36, 23.7 306.19, 76.11 -69.27, -12.74 in-out in 8.717 Saltbr-out 4.0968 HRD-in -66.08, -48.44 73.53, 0.66 out-in-in SNCoii in-in ActLoopNT-in 2.8454 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -121.84, 167.68 APE9-dihe-na 128.52, -172.33 APE8-dihe-in -109.54, 116.11 APE8-rot-in 303.67 APE67-dihe-in -57.63, -18.12 -43.35, -51.59 APE12-dist-in 10.3467 APE11-dist-in 11.6456 APE10-dist-in 6.2992 APE9-dist-in 3.8249 None TPO342,TPO345 MSE192,MSE237,MSE265,MSE287,TPO342,MSE344,TPO345,MSE355,MSE418,MSE429,MSE457 XRAY 2.4 0.246 0.289 B 298.0 277.0 18 30 26 4 [[183, 456]] 1.0 2o8y Homo sapiens TKL_IRAK4_HUMAN TKL 3.9e-84 288.3 5.0 266.0 262.0 328 329 330 332 334 213 233 237 308 310 309 311.0 369 358 353 352 351 350 349 348 347 263 Interleukin-1 receptor-associated kinase 4

PDB: 2O8Y — TKL IRAK4_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name