PDB: 2JIT — TYR EGFR_HUMAN

Total number of chains: 2
Active chains: 1
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 1 50.0% 2JITA
DFGinter None 1 50.0% 2JITB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR EGFR EGFR_HUMAN 2JITA P00533 696 1016 1210.0 No_ligand No_ligand Active DFGin 5.1411 14.0407 BLAminus -143.75, -163.53 58.3, 96.79 -111.32, 23.77 293.79, 72.87 -42.77, -57.72 in-in in 8.2608 Saltbr-in 2.5023 HRD-in -58.72, -42.55 61.63, -2.2 in-in-in SNCiii in-in ActLoopNT-in 2.786 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -40.92, 138.22 APE9-dihe-in -145.55, 148.59 APE8-dihe-in -78.1, 90.66 APE8-rot-na 34.4 APE67-dihe-in -72.3, 17.7 -56.07, -43.84 APE12-dist-na 11.5326 APE11-dist-na 9.5445 APE10-dist-na 10.0762 APE9-dist-in 6.677 T790M None None XRAY 3.1 0.209 0.249 A 327.0 299.0 0 30 30 0 [[712, 970]] 1.0 2jit TYR_EGFR_HUMAN TYR 8e-88 300.2 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 2JITB P00533 697 1018 1210.0 No_ligand No_ligand Inactive DFGinter 8.6428 4.2683 None -65.09, 133.17 -114.41, 36.11 -84.27, 149.81 251.72, 154.26 60.91, 22.91 in-in in 8.0303 Saltbr-in 3.164 HRD-in -71.83, -62.45 88.36, -10.04 in-out-in SNCioi out-in ActLoopNT-out 4.3323 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -76.87, 136.57 APE9-dihe-in -138.24, 154.81 APE8-dihe-in -91.0, 80.78 APE8-rot-na 356.06 APE67-dihe-in -73.95, 11.71 -56.2, -43.16 APE12-dist-na 15.9826 APE11-dist-na 15.7725 APE10-dist-na 15.9676 APE9-dist-in 7.4115 T790M None None XRAY 3.1 0.209 0.249 B 327.0 312.0 0 30 30 0 [[712, 970]] 1.0 2jit TYR_EGFR_HUMAN TYR 8e-88 300.2 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor

PDB: 2JIT — TYR EGFR_HUMAN

Total number of chains: 2
Active chains: 1
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 1 50.0% 2JITA
DFGinter None 1 50.0% 2JITB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR EGFR EGFR_HUMAN 2JITA P00533 696 1016 1210.0 No_ligand No_ligand Active DFGin 5.1411 14.0407 BLAminus -143.75, -163.53 58.3, 96.79 -111.32, 23.77 293.79, 72.87 -42.77, -57.72 in-in in 8.2608 Saltbr-in 2.5023 HRD-in -58.72, -42.55 61.63, -2.2 in-in-in SNCiii in-in ActLoopNT-in 2.786 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -40.92, 138.22 APE9-dihe-in -145.55, 148.59 APE8-dihe-in -78.1, 90.66 APE8-rot-na 34.4 APE67-dihe-in -72.3, 17.7 -56.07, -43.84 APE12-dist-na 11.5326 APE11-dist-na 9.5445 APE10-dist-na 10.0762 APE9-dist-in 6.677 T790M None None XRAY 3.1 0.209 0.249 A 327.0 299.0 0 30 30 0 [[712, 970]] 1.0 2jit Homo sapiens TYR_EGFR_HUMAN TYR 8e-88 300.2 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 2JITB P00533 697 1018 1210.0 No_ligand No_ligand Inactive DFGinter 8.6428 4.2683 None -65.09, 133.17 -114.41, 36.11 -84.27, 149.81 251.72, 154.26 60.91, 22.91 in-in in 8.0303 Saltbr-in 3.164 HRD-in -71.83, -62.45 88.36, -10.04 in-out-in SNCioi out-in ActLoopNT-out 4.3323 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -76.87, 136.57 APE9-dihe-in -138.24, 154.81 APE8-dihe-in -91.0, 80.78 APE8-rot-na 356.06 APE67-dihe-in -73.95, 11.71 -56.2, -43.16 APE12-dist-na 15.9826 APE11-dist-na 15.7725 APE10-dist-na 15.9676 APE9-dist-in 7.4115 T790M None None XRAY 3.1 0.209 0.249 B 327.0 312.0 0 30 30 0 [[712, 970]] 1.0 2jit Homo sapiens TYR_EGFR_HUMAN TYR 8e-88 300.2 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor

PDB: 2JIT — TYR EGFR_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name