PDB: 2GQG — TYR ABL1_HUMAN

Total number of chains: 2
Active chains: 1
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 2GQGA

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
TYR ABL1 ABL1_HUMAN 2GQGA 2.4 Inactive DFGin‑BLAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai 1N1 Type1 229 - 500 0 PTR393 None Tyrosine-protein kinase ABL1
TYR ABL1 ABL1_HUMAN 2GQGB 2.4 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai 1N1 Type1.5_Back 229 - 499 0 PTR393 None Tyrosine-protein kinase ABL1

PDB: 2GQG — TYR ABL1_HUMAN

Total number of chains: 2
Active chains: 1
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 2GQGA

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
TYR ABL1 ABL1_HUMAN 2GQGA 2.4 Inactive DFGin‑BLAminus in-in in-out TYR APEdihe_oiiai APEdist_aaai 1N1 Type1 229 - 500 0 PTR393 None Tyrosine-protein kinase ABL1 Homo sapiens
TYR ABL1 ABL1_HUMAN 2GQGB 2.4 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai 1N1 Type1.5_Back 229 - 499 0 PTR393 None Tyrosine-protein kinase ABL1 Homo sapiens

PDB: 2GQG — TYR ABL1_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism