PDB: 2FB8 — TKL BRAF_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 2FB8A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL BRAF BRAF_HUMAN 2FB8A P15056 449 720 766.0 215:102 Type1 Inactive DFGin 6.4899 14.2472 BLAminus -146.27, -176.88 62.65, 94.56 -116.52, 20.29 274.9, 82.58 -45.53, -44.52 in-in in 8.8846 Saltbr-in 2.9188 HRD-in -63.2, -49.5 66.34, 11.44 in-in-out SNCiio in-out ActLoopNT-in 3.0934 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_nnoi APE10-dihe-na 999.0, 14.21 APE9-dihe-na 115.89, -169.69 APE8-dihe-in -101.37, 114.44 APE8-rot-in 279.54 APE67-dihe-in -65.73, -0.43 -52.43, -50.98 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-out 10.6854 APE9-dist-in 5.9578 None None None XRAY 2.9 0.203 0.291 A 281.0 259.0 13 30 17 13 [[457, 716]] 1.0 2fb8 TKL_BRAF_HUMAN TKL 7.9e-82 280.7 4.0 266.0 263.0 593 594 595 597 599 483 501 505 573 575 574 576.0 638 623 618 617 616 615 614 613 612 530 Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 2FB8B P15056 449 720 766.0 215:101 Type1 Inactive DFGin 6.4785 14.1482 BLAminus -111.07, -173.65 45.12, 91.89 -99.34, 30.47 289.04, 74.24 -44.77, -52.25 in-in in 8.6694 Saltbr-in 3.2145 HRD-in -70.79, -48.1 71.94, -5.57 in-in-out SNCiio in-out ActLoopNT-in 3.0361 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_nnio APE10-dihe-na 999.0, 56.52 APE9-dihe-na 105.86, -135.38 APE8-dihe-in -106.43, 95.16 APE8-rot-in 246.18 APE67-dihe-in -77.85, -8.64 -35.19, -42.15 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-in 7.872 APE9-dist-out 6.8336 None None None XRAY 2.9 0.203 0.291 B 281.0 259.0 13 30 17 13 [[457, 716]] 1.0 2fb8 TKL_BRAF_HUMAN TKL 7.9e-82 280.7 4.0 266.0 263.0 593 594 595 597 599 483 501 505 573 575 574 576.0 638 623 618 617 616 615 614 613 612 530 Serine/threonine-protein kinase B-raf

PDB: 2FB8 — TKL BRAF_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 2FB8A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL BRAF BRAF_HUMAN 2FB8A P15056 449 720 766.0 215:102 Type1 Inactive DFGin 6.4899 14.2472 BLAminus -146.27, -176.88 62.65, 94.56 -116.52, 20.29 274.9, 82.58 -45.53, -44.52 in-in in 8.8846 Saltbr-in 2.9188 HRD-in -63.2, -49.5 66.34, 11.44 in-in-out SNCiio in-out ActLoopNT-in 3.0934 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_nnoi APE10-dihe-na 999.0, 14.21 APE9-dihe-na 115.89, -169.69 APE8-dihe-in -101.37, 114.44 APE8-rot-in 279.54 APE67-dihe-in -65.73, -0.43 -52.43, -50.98 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-out 10.6854 APE9-dist-in 5.9578 None None None XRAY 2.9 0.203 0.291 A 281.0 259.0 13 30 17 13 [[457, 716]] 1.0 2fb8 Homo sapiens TKL_BRAF_HUMAN TKL 7.9e-82 280.7 4.0 266.0 263.0 593 594 595 597 599 483 501 505 573 575 574 576.0 638 623 618 617 616 615 614 613 612 530 Serine/threonine-protein kinase B-raf
TKL BRAF BRAF_HUMAN 2FB8B P15056 449 720 766.0 215:101 Type1 Inactive DFGin 6.4785 14.1482 BLAminus -111.07, -173.65 45.12, 91.89 -99.34, 30.47 289.04, 74.24 -44.77, -52.25 in-in in 8.6694 Saltbr-in 3.2145 HRD-in -70.79, -48.1 71.94, -5.57 in-in-out SNCiio in-out ActLoopNT-in 3.0361 ActLoopCT-out nonTYR APEdihe_aaiii APEdist_nnio APE10-dihe-na 999.0, 56.52 APE9-dihe-na 105.86, -135.38 APE8-dihe-in -106.43, 95.16 APE8-rot-in 246.18 APE67-dihe-in -77.85, -8.64 -35.19, -42.15 APE12-dist-none 999.0 APE11-dist-none 999.0 APE10-dist-in 7.872 APE9-dist-out 6.8336 None None None XRAY 2.9 0.203 0.291 B 281.0 259.0 13 30 17 13 [[457, 716]] 1.0 2fb8 Homo sapiens TKL_BRAF_HUMAN TKL 7.9e-82 280.7 4.0 266.0 263.0 593 594 595 597 599 483 501 505 573 575 574 576.0 638 623 618 617 616 615 614 613 612 530 Serine/threonine-protein kinase B-raf

PDB: 2FB8 — TKL BRAF_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name