PDB: 2B7A — TYR JAK2_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 2 100.0% 2B7AA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR JAK2-2 JAK2_HUMAN 2B7AA O60674 843 1132 1132.0 IZA:2001 Type1 Inactive DFGin 6.0912 13.6248 ABAminus -114.38, -2.16 -148.17, 146.16 -136.98, 30.75 299.01, 90.79 -59.91, -29.0 in-in in 8.5694 Saltbr-in 2.7064 HRD-in -66.9, -48.29 72.12, 2.52 in-in-in SNCiii in-in ActLoopNT-in 2.7921 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -105.58, 136.09 APE9-dihe-in -109.08, 151.35 APE8-dihe-in -75.49, 67.84 APE8-rot-na 28.43 APE67-dihe-in -82.12, -0.33 -57.73, -26.93 APE12-dist-na 12.8376 APE11-dist-na 12.7835 APE10-dist-na 13.0283 APE9-dist-in 7.774 N1129Q PTR1007,PTR1008 PTR1007,PTR1008 XRAY 2.0 0.211 0.249 A 293.0 286.0 4 31 31 0 [[545, 807], [849, 1125]] 2.0 2b7a TYR_JAK2-2_HUMAN TYR 2.4e-87 298.5 1.0 260.0 260.0 993 994 995 997 999 882 898 902 973 975 974 976.0 1036 1024 1019 1018 1017 1016 1015 1014 1013 930 Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 2B7AB O60674 840 1132 1132.0 IZA:2002 Type1 Inactive DFGin 6.3444 13.9965 ABAminus -119.31, 4.3 -151.2, 143.13 -134.49, 30.64 293.9, 87.84 -61.34, -27.31 in-in in 8.5535 Saltbr-in 2.6987 HRD-in -66.93, -45.51 70.91, -4.56 in-in-in SNCiii in-in ActLoopNT-in 2.7529 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -67.16, 133.69 APE9-dihe-in -107.45, 143.93 APE8-dihe-in -73.92, 74.12 APE8-rot-na 26.37 APE67-dihe-in -82.73, -2.12 -60.01, -26.2 APE12-dist-na 12.4548 APE11-dist-na 10.8183 APE10-dist-na 12.4433 APE9-dist-in 7.5838 N1129Q PTR1007,PTR1008 PTR1007,PTR1008 XRAY 2.0 0.211 0.249 B 293.0 289.0 4 31 31 0 [[545, 807], [849, 1125]] 2.0 2b7a TYR_JAK2-2_HUMAN TYR 2.4e-87 298.5 1.0 260.0 260.0 993 994 995 997 999 882 898 902 973 975 974 976.0 1036 1024 1019 1018 1017 1016 1015 1014 1013 930 Tyrosine-protein kinase JAK2

PDB: 2B7A — TYR JAK2_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 2 100.0% 2B7AA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR JAK2-2 JAK2_HUMAN 2B7AA O60674 843 1132 1132.0 IZA:2001 Type1 Inactive DFGin 6.0912 13.6248 ABAminus -114.38, -2.16 -148.17, 146.16 -136.98, 30.75 299.01, 90.79 -59.91, -29.0 in-in in 8.5694 Saltbr-in 2.7064 HRD-in -66.9, -48.29 72.12, 2.52 in-in-in SNCiii in-in ActLoopNT-in 2.7921 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -105.58, 136.09 APE9-dihe-in -109.08, 151.35 APE8-dihe-in -75.49, 67.84 APE8-rot-na 28.43 APE67-dihe-in -82.12, -0.33 -57.73, -26.93 APE12-dist-na 12.8376 APE11-dist-na 12.7835 APE10-dist-na 13.0283 APE9-dist-in 7.774 N1129Q PTR1007,PTR1008 PTR1007,PTR1008 XRAY 2.0 0.211 0.249 A 293.0 286.0 4 31 31 0 [[545, 807], [849, 1125]] 2.0 2b7a Homo sapiens TYR_JAK2-2_HUMAN TYR 2.4e-87 298.5 1.0 260.0 260.0 993 994 995 997 999 882 898 902 973 975 974 976.0 1036 1024 1019 1018 1017 1016 1015 1014 1013 930 Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 2B7AB O60674 840 1132 1132.0 IZA:2002 Type1 Inactive DFGin 6.3444 13.9965 ABAminus -119.31, 4.3 -151.2, 143.13 -134.49, 30.64 293.9, 87.84 -61.34, -27.31 in-in in 8.5535 Saltbr-in 2.6987 HRD-in -66.93, -45.51 70.91, -4.56 in-in-in SNCiii in-in ActLoopNT-in 2.7529 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -67.16, 133.69 APE9-dihe-in -107.45, 143.93 APE8-dihe-in -73.92, 74.12 APE8-rot-na 26.37 APE67-dihe-in -82.73, -2.12 -60.01, -26.2 APE12-dist-na 12.4548 APE11-dist-na 10.8183 APE10-dist-na 12.4433 APE9-dist-in 7.5838 N1129Q PTR1007,PTR1008 PTR1007,PTR1008 XRAY 2.0 0.211 0.249 B 293.0 289.0 4 31 31 0 [[545, 807], [849, 1125]] 2.0 2b7a Homo sapiens TYR_JAK2-2_HUMAN TYR 2.4e-87 298.5 1.0 260.0 260.0 993 994 995 997 999 882 898 902 973 975 974 976.0 1036 1024 1019 1018 1017 1016 1015 1014 1013 930 Tyrosine-protein kinase JAK2

PDB: 2B7A — TYR JAK2_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name