Ligand: YT8

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 2 100.0% 8G8XB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR JAK2-2 JAK2_HUMAN 8G8XA O60674 842 1130 1132.0 YT8:1201 Type1 Inactive DFGin 6.2874 13.6212 ABAminus -128.64, 13.57 -157.75, 139.94 -132.4, 23.74 294.22, 91.25 -59.33, -23.18 in-in in 8.2746 Saltbr-in 2.663 HRD-in -73.44, -46.22 72.51, -9.33 in-in-in SNCiii in-in ActLoopNT-in 2.8018 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -57.22, 138.12 APE9-dihe-in -120.1, 150.86 APE8-dihe-in -76.91, 73.06 APE8-rot-na 33.65 APE67-dihe-in -77.05, 1.87 -66.0, -28.97 APE12-dist-na 13.8908 APE11-dist-na 11.2515 APE10-dist-na 12.3071 APE9-dist-in 7.5894 M1073S,F1076T PTR1007,PTR1008 PTR1007,PTR1008 XRAY 1.97 0.197 0.236 A 318.0 279.0 10 31 31 0 [[545, 807], [849, 1125]] 2.0 8g8x TYR_JAK2-2_HUMAN TYR 7.8e-87 296.9 1.0 260.0 260.0 993 994 995 997 999 882 898 902 973 975 974 976.0 1036 1024 1019 1018 1017 1016 1015 1014 1013 930 Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 8G8XB O60674 842 1130 1132.0 YT8:1201 Type1 Inactive DFGin 6.3053 13.6248 ABAminus -131.5, 13.18 -154.49, 140.48 -130.41, 26.19 295.07, 93.87 -67.86, -20.04 in-in in 8.3176 Saltbr-in 2.6605 HRD-in -75.4, -49.99 77.29, -20.66 in-in-none SNCiin in-none ActLoopNT-in 2.7801 ActLoopCT-none TYR APEdihe_niiai APEdist_aaai APE10-dihe-none 999.0, 148.7 APE9-dihe-in -121.49, 150.25 APE8-dihe-in -78.15, 75.05 APE8-rot-na 34.71 APE67-dihe-in -78.89, 2.08 -66.22, -28.7 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 12.3945 APE9-dist-in 7.624 M1073S,F1076T PTR1007,PTR1008 PTR1007,PTR1008 XRAY 1.97 0.197 0.236 B 318.0 283.0 6 31 28 3 [[545, 807], [849, 1125]] 2.0 8g8x TYR_JAK2-2_HUMAN TYR 7.8e-87 296.9 1.0 260.0 260.0 993 994 995 997 999 882 898 902 973 975 974 976.0 1036 1024 1019 1018 1017 1016 1015 1014 1013 930 Tyrosine-protein kinase JAK2

Ligand: YT8

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 2 100.0% 8G8XB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR JAK2-2 JAK2_HUMAN 8G8XA O60674 842 1130 1132.0 YT8:1201 Type1 Inactive DFGin 6.2874 13.6212 ABAminus -128.64, 13.57 -157.75, 139.94 -132.4, 23.74 294.22, 91.25 -59.33, -23.18 in-in in 8.2746 Saltbr-in 2.663 HRD-in -73.44, -46.22 72.51, -9.33 in-in-in SNCiii in-in ActLoopNT-in 2.8018 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -57.22, 138.12 APE9-dihe-in -120.1, 150.86 APE8-dihe-in -76.91, 73.06 APE8-rot-na 33.65 APE67-dihe-in -77.05, 1.87 -66.0, -28.97 APE12-dist-na 13.8908 APE11-dist-na 11.2515 APE10-dist-na 12.3071 APE9-dist-in 7.5894 M1073S,F1076T PTR1007,PTR1008 PTR1007,PTR1008 XRAY 1.97 0.197 0.236 A 318.0 279.0 10 31 31 0 [[545, 807], [849, 1125]] 2.0 8g8x Homo sapiens TYR_JAK2-2_HUMAN TYR 7.8e-87 296.9 1.0 260.0 260.0 993 994 995 997 999 882 898 902 973 975 974 976.0 1036 1024 1019 1018 1017 1016 1015 1014 1013 930 Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 8G8XB O60674 842 1130 1132.0 YT8:1201 Type1 Inactive DFGin 6.3053 13.6248 ABAminus -131.5, 13.18 -154.49, 140.48 -130.41, 26.19 295.07, 93.87 -67.86, -20.04 in-in in 8.3176 Saltbr-in 2.6605 HRD-in -75.4, -49.99 77.29, -20.66 in-in-none SNCiin in-none ActLoopNT-in 2.7801 ActLoopCT-none TYR APEdihe_niiai APEdist_aaai APE10-dihe-none 999.0, 148.7 APE9-dihe-in -121.49, 150.25 APE8-dihe-in -78.15, 75.05 APE8-rot-na 34.71 APE67-dihe-in -78.89, 2.08 -66.22, -28.7 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 12.3945 APE9-dist-in 7.624 M1073S,F1076T PTR1007,PTR1008 PTR1007,PTR1008 XRAY 1.97 0.197 0.236 B 318.0 283.0 6 31 28 3 [[545, 807], [849, 1125]] 2.0 8g8x Homo sapiens TYR_JAK2-2_HUMAN TYR 7.8e-87 296.9 1.0 260.0 260.0 993 994 995 997 999 882 898 902 973 975 974 976.0 1036 1024 1019 1018 1017 1016 1015 1014 1013 930 Tyrosine-protein kinase JAK2

Ligand: YT8

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name