Ligand: YT0

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 2 100.0% 8G8OA

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
TYR JAK2-2 JAK2_HUMAN 8G8OA 2.2 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai YT0 Type1 842 - 1130 0 PTR1007,PTR1008 M1073S,F1076T Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 8G8OB 2.2 Inactive DFGin‑ABAminus in-in in-none TYR APEdihe_niiai APEdist_aaai YT0 Type1 843 - 1130 0 PTR1007,PTR1008 M1073S,F1076T Tyrosine-protein kinase JAK2

Ligand: YT0

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 2 100.0% 8G8OA

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
TYR JAK2-2 JAK2_HUMAN 8G8OA 2.2 Inactive DFGin‑ABAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai YT0 Type1 842 - 1130 0 PTR1007,PTR1008 M1073S,F1076T Tyrosine-protein kinase JAK2 Homo sapiens
TYR JAK2-2 JAK2_HUMAN 8G8OB 2.2 Inactive DFGin‑ABAminus in-in in-none TYR APEdihe_niiai APEdist_aaai YT0 Type1 843 - 1130 0 PTR1007,PTR1008 M1073S,F1076T Tyrosine-protein kinase JAK2 Homo sapiens

Ligand: YT0

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative

Download database table as tsv Go to Advanced Page
Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism