Ligand: YK0

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 4 100.0% 8V2LA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL IRAK4 IRAK4_HUMAN 8V2LA Q9NWZ3 164 459 460.0 YK0:501 Type1 Inactive DFGin 6.6037 13.4056 BLAminus -121.21, 172.86 64.77, 85.79 -107.22, 18.27 310.33, 96.01 -58.61, -41.96 in-out in 8.0401 Saltbr-out 4.2802 HRD-in -62.46, -51.84 78.02, 3.1 out-in-in SNCoii in-in ActLoopNT-in 2.6112 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -134.97, 166.5 APE9-dihe-na 120.32, -177.29 APE8-dihe-in -108.05, 112.93 APE8-rot-in 310.64 APE67-dihe-in -64.75, -16.58 -36.82, -53.61 APE12-dist-in 9.3452 APE11-dist-in 11.3313 APE10-dist-in 5.8782 APE9-dist-in 3.2645 None TPO342,TPO345,SEP346 TPO342,TPO345,SEP346 XRAY 2.43 0.255 0.302 A 327.0 291.0 5 30 25 5 [[183, 456]] 1.0 8v2l TKL_IRAK4_HUMAN TKL 5.5e-84 287.8 5.0 266.0 262.0 328 329 330 332 334 213 233 237 308 310 309 311.0 369 358 353 352 351 350 349 348 347 263 Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 8V2LB Q9NWZ3 163 459 460.0 YK0:501 Type1 Inactive DFGin 6.6197 13.3492 BLAminus -120.96, 172.67 64.91, 85.77 -106.56, 17.9 310.1, 96.45 -58.62, -41.82 in-out in 7.9848 Saltbr-out 3.8758 HRD-in -62.59, -51.36 77.4, 3.79 out-in-in SNCoii in-in ActLoopNT-in 2.6128 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -134.09, 166.75 APE9-dihe-na 122.3, -175.29 APE8-dihe-in -107.71, 112.62 APE8-rot-in 309.44 APE67-dihe-in -64.15, -17.62 -36.19, -53.73 APE12-dist-in 9.2748 APE11-dist-in 11.2494 APE10-dist-in 5.7935 APE9-dist-in 3.2243 None TPO342,TPO345,SEP346 TPO342,TPO345,SEP346 XRAY 2.43 0.255 0.302 B 327.0 292.0 5 30 25 5 [[183, 456]] 1.0 8v2l TKL_IRAK4_HUMAN TKL 5.5e-84 287.8 5.0 266.0 262.0 328 329 330 332 334 213 233 237 308 310 309 311.0 369 358 353 352 351 350 349 348 347 263 Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 8V2LC Q9NWZ3 164 459 460.0 YK0:501 Type1 Inactive DFGin 6.5519 13.5417 BLAminus -121.25, 173.26 64.05, 86.32 -106.85, 17.63 309.75, 95.82 -58.65, -40.64 in-out in 7.9726 Saltbr-out 3.8686 HRD-in -62.33, -51.39 77.94, 3.4 out-in-in SNCoii in-in ActLoopNT-in 2.607 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -135.03, 167.23 APE9-dihe-na 120.49, -177.04 APE8-dihe-in -107.34, 112.53 APE8-rot-in 310.89 APE67-dihe-in -65.65, -16.07 -36.38, -53.95 APE12-dist-in 9.2763 APE11-dist-in 11.2987 APE10-dist-in 5.8444 APE9-dist-in 3.232 None TPO342,TPO345,SEP346 TPO342,TPO345,SEP346 XRAY 2.43 0.255 0.302 C 327.0 291.0 5 30 25 5 [[183, 456]] 1.0 8v2l TKL_IRAK4_HUMAN TKL 5.5e-84 287.8 5.0 266.0 262.0 328 329 330 332 334 213 233 237 308 310 309 311.0 369 358 353 352 351 350 349 348 347 263 Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 8V2LD Q9NWZ3 164 459 460.0 YK0:501 Type1 Inactive DFGin 6.5695 13.4784 BLAminus -121.17, 172.07 65.62, 86.14 -107.29, 16.86 310.43, 82.27 -58.81, -41.47 in-out in 7.8793 Saltbr-out 3.8558 HRD-in -62.38, -51.53 78.2, 3.12 out-in-in SNCoii in-in ActLoopNT-in 2.6133 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -133.11, 167.04 APE9-dihe-na 120.53, -178.59 APE8-dihe-in -107.42, 112.59 APE8-rot-in 311.17 APE67-dihe-in -65.49, -16.09 -36.28, -53.87 APE12-dist-in 9.5025 APE11-dist-in 11.3431 APE10-dist-in 5.9014 APE9-dist-in 3.2603 None TPO342,TPO345,SEP346 TPO342,TPO345,SEP346 XRAY 2.43 0.255 0.302 D 327.0 291.0 5 30 25 5 [[183, 456]] 1.0 8v2l TKL_IRAK4_HUMAN TKL 5.5e-84 287.8 5.0 266.0 262.0 328 329 330 332 334 213 233 237 308 310 309 311.0 369 358 353 352 351 350 349 348 347 263 Interleukin-1 receptor-associated kinase 4

Ligand: YK0

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 4 100.0% 8V2LA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL IRAK4 IRAK4_HUMAN 8V2LA Q9NWZ3 164 459 460.0 YK0:501 Type1 Inactive DFGin 6.6037 13.4056 BLAminus -121.21, 172.86 64.77, 85.79 -107.22, 18.27 310.33, 96.01 -58.61, -41.96 in-out in 8.0401 Saltbr-out 4.2802 HRD-in -62.46, -51.84 78.02, 3.1 out-in-in SNCoii in-in ActLoopNT-in 2.6112 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -134.97, 166.5 APE9-dihe-na 120.32, -177.29 APE8-dihe-in -108.05, 112.93 APE8-rot-in 310.64 APE67-dihe-in -64.75, -16.58 -36.82, -53.61 APE12-dist-in 9.3452 APE11-dist-in 11.3313 APE10-dist-in 5.8782 APE9-dist-in 3.2645 None TPO342,TPO345,SEP346 TPO342,TPO345,SEP346 XRAY 2.43 0.255 0.302 A 327.0 291.0 5 30 25 5 [[183, 456]] 1.0 8v2l Homo sapiens TKL_IRAK4_HUMAN TKL 5.5e-84 287.8 5.0 266.0 262.0 328 329 330 332 334 213 233 237 308 310 309 311.0 369 358 353 352 351 350 349 348 347 263 Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 8V2LB Q9NWZ3 163 459 460.0 YK0:501 Type1 Inactive DFGin 6.6197 13.3492 BLAminus -120.96, 172.67 64.91, 85.77 -106.56, 17.9 310.1, 96.45 -58.62, -41.82 in-out in 7.9848 Saltbr-out 3.8758 HRD-in -62.59, -51.36 77.4, 3.79 out-in-in SNCoii in-in ActLoopNT-in 2.6128 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -134.09, 166.75 APE9-dihe-na 122.3, -175.29 APE8-dihe-in -107.71, 112.62 APE8-rot-in 309.44 APE67-dihe-in -64.15, -17.62 -36.19, -53.73 APE12-dist-in 9.2748 APE11-dist-in 11.2494 APE10-dist-in 5.7935 APE9-dist-in 3.2243 None TPO342,TPO345,SEP346 TPO342,TPO345,SEP346 XRAY 2.43 0.255 0.302 B 327.0 292.0 5 30 25 5 [[183, 456]] 1.0 8v2l Homo sapiens TKL_IRAK4_HUMAN TKL 5.5e-84 287.8 5.0 266.0 262.0 328 329 330 332 334 213 233 237 308 310 309 311.0 369 358 353 352 351 350 349 348 347 263 Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 8V2LC Q9NWZ3 164 459 460.0 YK0:501 Type1 Inactive DFGin 6.5519 13.5417 BLAminus -121.25, 173.26 64.05, 86.32 -106.85, 17.63 309.75, 95.82 -58.65, -40.64 in-out in 7.9726 Saltbr-out 3.8686 HRD-in -62.33, -51.39 77.94, 3.4 out-in-in SNCoii in-in ActLoopNT-in 2.607 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -135.03, 167.23 APE9-dihe-na 120.49, -177.04 APE8-dihe-in -107.34, 112.53 APE8-rot-in 310.89 APE67-dihe-in -65.65, -16.07 -36.38, -53.95 APE12-dist-in 9.2763 APE11-dist-in 11.2987 APE10-dist-in 5.8444 APE9-dist-in 3.232 None TPO342,TPO345,SEP346 TPO342,TPO345,SEP346 XRAY 2.43 0.255 0.302 C 327.0 291.0 5 30 25 5 [[183, 456]] 1.0 8v2l Homo sapiens TKL_IRAK4_HUMAN TKL 5.5e-84 287.8 5.0 266.0 262.0 328 329 330 332 334 213 233 237 308 310 309 311.0 369 358 353 352 351 350 349 348 347 263 Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 8V2LD Q9NWZ3 164 459 460.0 YK0:501 Type1 Inactive DFGin 6.5695 13.4784 BLAminus -121.17, 172.07 65.62, 86.14 -107.29, 16.86 310.43, 82.27 -58.81, -41.47 in-out in 7.8793 Saltbr-out 3.8558 HRD-in -62.38, -51.53 78.2, 3.12 out-in-in SNCoii in-in ActLoopNT-in 2.6133 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -133.11, 167.04 APE9-dihe-na 120.53, -178.59 APE8-dihe-in -107.42, 112.59 APE8-rot-in 311.17 APE67-dihe-in -65.49, -16.09 -36.28, -53.87 APE12-dist-in 9.5025 APE11-dist-in 11.3431 APE10-dist-in 5.9014 APE9-dist-in 3.2603 None TPO342,TPO345,SEP346 TPO342,TPO345,SEP346 XRAY 2.43 0.255 0.302 D 327.0 291.0 5 30 25 5 [[183, 456]] 1.0 8v2l Homo sapiens TKL_IRAK4_HUMAN TKL 5.5e-84 287.8 5.0 266.0 262.0 328 329 330 332 334 213 233 237 308 310 309 311.0 369 358 353 352 351 350 349 348 347 263 Interleukin-1 receptor-associated kinase 4

Ligand: YK0

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name