Ligand: YFA

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 4 100.0% 7LTXB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR EGFR EGFR_HUMAN 7LTXA P00533 700 1007 1210.0 ANP:1101,YFA:1103 ATPlike,Type3 Inactive DFGin 5.2481 14.5643 BLBplus -135.35, 163.04 64.03, 33.94 -82.37, 179.4 48.16, 87.26 -162.42, -162.89 out-out out 13.1822 Saltbr-out 10.5993 HRD-in -67.02, -61.48 82.46, -5.8 out-none-out SNCono none-out ActLoopNT-none 999.0 ActLoopCT-out TYR APEdihe_nniai APEdist_aaao APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 124.93 APE8-dihe-in -80.94, 68.72 APE8-rot-na 31.43 APE67-dihe-in -70.18, -9.53 -51.9, -44.48 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-out 8.02 T790M,V948R None None XRAY 2.3 0.187 0.216 A 331.0 292.0 16 30 14 16 [[712, 970]] 1.0 7ltx TYR_EGFR_HUMAN TYR 6.3e-88 300.5 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7LTXB P00533 700 1007 1210.0 ANP:1101,YFA:1103 ATPlike,Type3 Inactive DFGin 5.1967 14.4947 BLBplus -136.17, 169.66 62.42, 34.77 -78.22, 170.05 42.44, 90.17 -152.16, -165.64 out-out out 13.123 Saltbr-out 10.2264 HRD-in -65.63, -61.11 82.51, -6.05 out-out-none SNCoon out-none ActLoopNT-out 9.2387 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 125.13 APE8-dihe-in -82.01, 66.41 APE8-rot-na 31.46 APE67-dihe-in -73.58, -7.26 -49.71, -42.88 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.8286 T790M,V948R None None XRAY 2.3 0.187 0.216 B 331.0 293.0 15 30 15 15 [[712, 970]] 1.0 7ltx TYR_EGFR_HUMAN TYR 6.3e-88 300.5 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7LTXC P00533 700 1007 1210.0 ANP:1101,YFA:1103 ATPlike,Type3 Inactive DFGin 5.1227 14.5107 BLBplus -136.55, 165.71 63.6, 32.17 -87.45, 156.27 46.73, 94.27 148.1, 156.05 out-out out 13.0711 Saltbr-out 10.0756 HRD-in -65.09, -59.89 81.29, -6.26 out-none-none SNConn none-none ActLoopNT-none 999.0 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 124.8 APE8-dihe-in -79.63, 67.92 APE8-rot-na 31.3 APE67-dihe-in -72.94, -5.81 -52.93, -44.7 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.8643 T790M,V948R None None XRAY 2.3 0.187 0.216 C 331.0 292.0 16 30 14 16 [[712, 970]] 1.0 7ltx TYR_EGFR_HUMAN TYR 6.3e-88 300.5 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7LTXD P00533 700 1007 1210.0 ANP:1101,YFA:1103 ATPlike,Type3 Inactive DFGin 5.3456 14.4432 BLBplus -137.08, 165.99 63.56, 34.05 -81.77, 167.16 44.82, 94.68 -177.57, 165.83 out-out out 12.9855 Saltbr-out 10.3401 HRD-in -68.33, -62.57 83.39, -4.99 out-out-none SNCoon out-none ActLoopNT-out 9.4938 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 124.9 APE8-dihe-in -80.86, 67.56 APE8-rot-na 30.12 APE67-dihe-in -73.23, -5.97 -50.49, -42.58 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.9168 T790M,V948R None None XRAY 2.3 0.187 0.216 D 331.0 293.0 15 30 15 15 [[712, 970]] 1.0 7ltx TYR_EGFR_HUMAN TYR 6.3e-88 300.5 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor

Ligand: YFA

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 4 100.0% 7LTXB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR EGFR EGFR_HUMAN 7LTXA P00533 700 1007 1210.0 ANP:1101,YFA:1103 ATPlike,Type3 Inactive DFGin 5.2481 14.5643 BLBplus -135.35, 163.04 64.03, 33.94 -82.37, 179.4 48.16, 87.26 -162.42, -162.89 out-out out 13.1822 Saltbr-out 10.5993 HRD-in -67.02, -61.48 82.46, -5.8 out-none-out SNCono none-out ActLoopNT-none 999.0 ActLoopCT-out TYR APEdihe_nniai APEdist_aaao APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 124.93 APE8-dihe-in -80.94, 68.72 APE8-rot-na 31.43 APE67-dihe-in -70.18, -9.53 -51.9, -44.48 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-out 8.02 T790M,V948R None None XRAY 2.3 0.187 0.216 A 331.0 292.0 16 30 14 16 [[712, 970]] 1.0 7ltx Homo sapiens TYR_EGFR_HUMAN TYR 6.3e-88 300.5 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7LTXB P00533 700 1007 1210.0 ANP:1101,YFA:1103 ATPlike,Type3 Inactive DFGin 5.1967 14.4947 BLBplus -136.17, 169.66 62.42, 34.77 -78.22, 170.05 42.44, 90.17 -152.16, -165.64 out-out out 13.123 Saltbr-out 10.2264 HRD-in -65.63, -61.11 82.51, -6.05 out-out-none SNCoon out-none ActLoopNT-out 9.2387 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 125.13 APE8-dihe-in -82.01, 66.41 APE8-rot-na 31.46 APE67-dihe-in -73.58, -7.26 -49.71, -42.88 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.8286 T790M,V948R None None XRAY 2.3 0.187 0.216 B 331.0 293.0 15 30 15 15 [[712, 970]] 1.0 7ltx Homo sapiens TYR_EGFR_HUMAN TYR 6.3e-88 300.5 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7LTXC P00533 700 1007 1210.0 ANP:1101,YFA:1103 ATPlike,Type3 Inactive DFGin 5.1227 14.5107 BLBplus -136.55, 165.71 63.6, 32.17 -87.45, 156.27 46.73, 94.27 148.1, 156.05 out-out out 13.0711 Saltbr-out 10.0756 HRD-in -65.09, -59.89 81.29, -6.26 out-none-none SNConn none-none ActLoopNT-none 999.0 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 124.8 APE8-dihe-in -79.63, 67.92 APE8-rot-na 31.3 APE67-dihe-in -72.94, -5.81 -52.93, -44.7 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.8643 T790M,V948R None None XRAY 2.3 0.187 0.216 C 331.0 292.0 16 30 14 16 [[712, 970]] 1.0 7ltx Homo sapiens TYR_EGFR_HUMAN TYR 6.3e-88 300.5 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7LTXD P00533 700 1007 1210.0 ANP:1101,YFA:1103 ATPlike,Type3 Inactive DFGin 5.3456 14.4432 BLBplus -137.08, 165.99 63.56, 34.05 -81.77, 167.16 44.82, 94.68 -177.57, 165.83 out-out out 12.9855 Saltbr-out 10.3401 HRD-in -68.33, -62.57 83.39, -4.99 out-out-none SNCoon out-none ActLoopNT-out 9.4938 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 124.9 APE8-dihe-in -80.86, 67.56 APE8-rot-na 30.12 APE67-dihe-in -73.23, -5.97 -50.49, -42.58 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.9168 T790M,V948R None None XRAY 2.3 0.187 0.216 D 331.0 293.0 15 30 15 15 [[712, 970]] 1.0 7ltx Homo sapiens TYR_EGFR_HUMAN TYR 6.3e-88 300.5 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor

Ligand: YFA

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name