Ligand: WTP

Total number of chains: 3
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 3 100.0% 8FE9A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR TNK2 ACK1_HUMAN 7KP6A Q07912 117 391 1038.0 WTP:401 Type1 Inactive DFGin 6.9868 13.0736 ABAminus -120.5, 2.81 -142.4, 134.01 -133.76, 28.84 306.02, 91.7 -68.06, -13.37 in-out in 8.7113 Saltbr-out 4.4386 HRD-in -78.88, -45.58 72.69, 3.73 out-in-in SNCoii in-in ActLoopNT-in 2.8144 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -141.02, 134.34 APE9-dihe-in -120.0, 134.77 APE8-dihe-in -57.68, 136.22 APE8-rot-na 336.49 APE67-dihe-in -65.99, -13.55 -58.92, -37.48 APE12-dist-na 12.2732 APE11-dist-na 7.2822 APE10-dist-na 10.4793 APE9-dist-in 5.5979 None None None XRAY 1.79 0.179 0.203 A 287.0 268.0 7 31 31 0 [[126, 387]] 1.0 7kp6 TYR_TNK2_HUMAN TYR 8.6e-86 293.4 1.0 259.0 259.0 269 270 271 273 275 158 177 181 249 251 250 252.0 312 300 295 294 293 292 291 290 289 206 Activated CDC42 kinase 1
TYR TNK2 ACK1_HUMAN 7KP6B Q07912 117 391 1038.0 WTP:401 Type1 Inactive DFGin 6.9711 13.4096 ABAminus -118.46, 0.28 -140.74, 140.65 -134.73, 29.67 302.28, 95.76 -64.4, -24.8 in-in in 8.4656 Saltbr-in 2.4826 HRD-in -80.63, -45.48 68.06, 5.55 in-in-none SNCiin in-none ActLoopNT-in 2.891 ActLoopCT-none TYR APEdihe_niiai APEdist_aaai APE10-dihe-none 999.0, 149.74 APE9-dihe-in -131.88, 157.91 APE8-dihe-in -71.95, 81.45 APE8-rot-na 27.93 APE67-dihe-in -74.26, -9.58 -63.95, -29.15 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 11.433 APE9-dist-in 6.5464 None None None XRAY 1.79 0.179 0.203 B 287.0 265.0 10 31 27 4 [[126, 387]] 1.0 7kp6 TYR_TNK2_HUMAN TYR 8.6e-86 293.4 1.0 259.0 259.0 269 270 271 273 275 158 177 181 249 251 250 252.0 312 300 295 294 293 292 291 290 289 206 Activated CDC42 kinase 1
TYR TNK2 ACK1_HUMAN 8FE9A Q07912 117 390 1038.0 WTP:401 Type1 Inactive DFGin 7.3704 13.0176 ABAminus -105.28, -25.45 -117.67, 141.58 -139.74, 24.77 304.61, 88.92 -62.34, -21.69 in-in in 9.1793 Saltbr-in 3.598 HRD-in -80.64, -42.58 70.6, 2.92 in-in-in SNCiii in-in ActLoopNT-in 2.9194 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -76.63, 116.01 APE9-dihe-in -111.81, 145.17 APE8-dihe-in -57.08, 126.3 APE8-rot-na 336.42 APE67-dihe-in -51.19, -45.24 -69.67, -25.96 APE12-dist-na 13.2508 APE11-dist-na 7.9549 APE10-dist-na 11.9713 APE9-dist-in 6.328 K161Q None None XRAY 3.2 0.192 0.228 A 287.0 274.0 0 31 31 0 [[126, 387]] 1.0 8fe9 TYR_TNK2_HUMAN TYR 1.7e-85 292.4 1.0 259.0 259.0 269 270 271 273 275 158 177 181 249 251 250 252.0 312 300 295 294 293 292 291 290 289 206 Activated CDC42 kinase 1

Ligand: WTP

Total number of chains: 3
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 3 100.0% 8FE9A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR TNK2 ACK1_HUMAN 7KP6A Q07912 117 391 1038.0 WTP:401 Type1 Inactive DFGin 6.9868 13.0736 ABAminus -120.5, 2.81 -142.4, 134.01 -133.76, 28.84 306.02, 91.7 -68.06, -13.37 in-out in 8.7113 Saltbr-out 4.4386 HRD-in -78.88, -45.58 72.69, 3.73 out-in-in SNCoii in-in ActLoopNT-in 2.8144 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -141.02, 134.34 APE9-dihe-in -120.0, 134.77 APE8-dihe-in -57.68, 136.22 APE8-rot-na 336.49 APE67-dihe-in -65.99, -13.55 -58.92, -37.48 APE12-dist-na 12.2732 APE11-dist-na 7.2822 APE10-dist-na 10.4793 APE9-dist-in 5.5979 None None None XRAY 1.79 0.179 0.203 A 287.0 268.0 7 31 31 0 [[126, 387]] 1.0 7kp6 Homo sapiens TYR_TNK2_HUMAN TYR 8.6e-86 293.4 1.0 259.0 259.0 269 270 271 273 275 158 177 181 249 251 250 252.0 312 300 295 294 293 292 291 290 289 206 Activated CDC42 kinase 1
TYR TNK2 ACK1_HUMAN 7KP6B Q07912 117 391 1038.0 WTP:401 Type1 Inactive DFGin 6.9711 13.4096 ABAminus -118.46, 0.28 -140.74, 140.65 -134.73, 29.67 302.28, 95.76 -64.4, -24.8 in-in in 8.4656 Saltbr-in 2.4826 HRD-in -80.63, -45.48 68.06, 5.55 in-in-none SNCiin in-none ActLoopNT-in 2.891 ActLoopCT-none TYR APEdihe_niiai APEdist_aaai APE10-dihe-none 999.0, 149.74 APE9-dihe-in -131.88, 157.91 APE8-dihe-in -71.95, 81.45 APE8-rot-na 27.93 APE67-dihe-in -74.26, -9.58 -63.95, -29.15 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 11.433 APE9-dist-in 6.5464 None None None XRAY 1.79 0.179 0.203 B 287.0 265.0 10 31 27 4 [[126, 387]] 1.0 7kp6 Homo sapiens TYR_TNK2_HUMAN TYR 8.6e-86 293.4 1.0 259.0 259.0 269 270 271 273 275 158 177 181 249 251 250 252.0 312 300 295 294 293 292 291 290 289 206 Activated CDC42 kinase 1
TYR TNK2 ACK1_HUMAN 8FE9A Q07912 117 390 1038.0 WTP:401 Type1 Inactive DFGin 7.3704 13.0176 ABAminus -105.28, -25.45 -117.67, 141.58 -139.74, 24.77 304.61, 88.92 -62.34, -21.69 in-in in 9.1793 Saltbr-in 3.598 HRD-in -80.64, -42.58 70.6, 2.92 in-in-in SNCiii in-in ActLoopNT-in 2.9194 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -76.63, 116.01 APE9-dihe-in -111.81, 145.17 APE8-dihe-in -57.08, 126.3 APE8-rot-na 336.42 APE67-dihe-in -51.19, -45.24 -69.67, -25.96 APE12-dist-na 13.2508 APE11-dist-na 7.9549 APE10-dist-na 11.9713 APE9-dist-in 6.328 K161Q None None XRAY 3.2 0.192 0.228 A 287.0 274.0 0 31 31 0 [[126, 387]] 1.0 8fe9 Homo sapiens TYR_TNK2_HUMAN TYR 1.7e-85 292.4 1.0 259.0 259.0 269 270 271 273 275 158 177 181 249 251 250 252.0 312 300 295 294 293 292 291 290 289 206 Activated CDC42 kinase 1

Ligand: WTP

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name