Ligand: VZJ

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin None 2 100.0% 7K7OA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR TYK2-1 TYK2_HUMAN 7K7OA P29597 580 867 1187.0 VZJ:901 Type1 Pseudo DFGin 7.3657 12.5647 None -66.43, 170.03 -67.36, 143.81 -70.91, 1.79 25.53, 145.85 78.47, -152.75 in-na in 9.2658 Saltbr-na 999.0 HRD-in -75.49, -66.33 85.17, 12.8 na-out-out SNCaoo out-out ActLoopNT-out 8.1813 ActLoopCT-out TYR APEdihe_oooao APEdist_aaao APE10-dihe-out -57.32, -40.35 APE9-dihe-out -58.15, -35.87 APE8-dihe-out -71.09, -6.29 APE8-rot-na 289.01 APE67-dihe-out -84.78, -2.19 -73.46, 133.77 APE12-dist-na 9.7653 APE11-dist-na 12.0883 APE10-dist-na 16.2662 APE9-dist-out 11.7631 None None None XRAY 2.82 0.181 0.252 A 317.0 257.0 32 24 24 0 [[589, 868], [897, 1171]] 2.0 7k7o TYR_TYK2-1_HUMAN TYR 5.4e-60 208.9 2.0 260.0 259.0 758 759 760 762 764 642 658 662 731 733 732 734.0 796 782 777 776 775 774 773 772 771 688 Non-receptor tyrosine-protein kinase TYK2
TYR TYK2-1 TYK2_HUMAN 7K7OB P29597 580 868 1187.0 VZJ:901 Type1 Pseudo DFGin 7.7233 12.2472 None -71.51, -175.68 -81.24, 151.01 -79.84, 4.8 35.04, 138.85 72.06, -152.96 in-na in 9.264 Saltbr-na 999.0 HRD-in -101.81, -60.3 88.52, -5.44 na-out-out SNCaoo out-out ActLoopNT-out 8.9231 ActLoopCT-out TYR APEdihe_oooao APEdist_aaao APE10-dihe-out -65.95, -43.16 APE9-dihe-out -55.55, -22.53 APE8-dihe-out -85.45, 0.22 APE8-rot-na 226.83 APE67-dihe-out -83.49, -4.03 -76.46, 136.55 APE12-dist-na 9.6282 APE11-dist-na 12.1992 APE10-dist-na 16.2685 APE9-dist-out 11.2834 None None None XRAY 2.82 0.181 0.252 B 317.0 257.0 32 24 24 0 [[589, 868], [897, 1171]] 2.0 7k7o TYR_TYK2-1_HUMAN TYR 5.4e-60 208.9 2.0 260.0 259.0 758 759 760 762 764 642 658 662 731 733 732 734.0 796 782 777 776 775 774 773 772 771 688 Non-receptor tyrosine-protein kinase TYK2

Ligand: VZJ

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin None 2 100.0% 7K7OA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR TYK2-1 TYK2_HUMAN 7K7OA P29597 580 867 1187.0 VZJ:901 Type1 Pseudo DFGin 7.3657 12.5647 None -66.43, 170.03 -67.36, 143.81 -70.91, 1.79 25.53, 145.85 78.47, -152.75 in-na in 9.2658 Saltbr-na 999.0 HRD-in -75.49, -66.33 85.17, 12.8 na-out-out SNCaoo out-out ActLoopNT-out 8.1813 ActLoopCT-out TYR APEdihe_oooao APEdist_aaao APE10-dihe-out -57.32, -40.35 APE9-dihe-out -58.15, -35.87 APE8-dihe-out -71.09, -6.29 APE8-rot-na 289.01 APE67-dihe-out -84.78, -2.19 -73.46, 133.77 APE12-dist-na 9.7653 APE11-dist-na 12.0883 APE10-dist-na 16.2662 APE9-dist-out 11.7631 None None None XRAY 2.82 0.181 0.252 A 317.0 257.0 32 24 24 0 [[589, 868], [897, 1171]] 2.0 7k7o Homo sapiens TYR_TYK2-1_HUMAN TYR 5.4e-60 208.9 2.0 260.0 259.0 758 759 760 762 764 642 658 662 731 733 732 734.0 796 782 777 776 775 774 773 772 771 688 Non-receptor tyrosine-protein kinase TYK2
TYR TYK2-1 TYK2_HUMAN 7K7OB P29597 580 868 1187.0 VZJ:901 Type1 Pseudo DFGin 7.7233 12.2472 None -71.51, -175.68 -81.24, 151.01 -79.84, 4.8 35.04, 138.85 72.06, -152.96 in-na in 9.264 Saltbr-na 999.0 HRD-in -101.81, -60.3 88.52, -5.44 na-out-out SNCaoo out-out ActLoopNT-out 8.9231 ActLoopCT-out TYR APEdihe_oooao APEdist_aaao APE10-dihe-out -65.95, -43.16 APE9-dihe-out -55.55, -22.53 APE8-dihe-out -85.45, 0.22 APE8-rot-na 226.83 APE67-dihe-out -83.49, -4.03 -76.46, 136.55 APE12-dist-na 9.6282 APE11-dist-na 12.1992 APE10-dist-na 16.2685 APE9-dist-out 11.2834 None None None XRAY 2.82 0.181 0.252 B 317.0 257.0 32 24 24 0 [[589, 868], [897, 1171]] 2.0 7k7o Homo sapiens TYR_TYK2-1_HUMAN TYR 5.4e-60 208.9 2.0 260.0 259.0 758 759 760 762 764 642 658 662 731 733 732 734.0 796 782 777 776 775 774 773 772 771 688 Non-receptor tyrosine-protein kinase TYK2

Ligand: VZJ

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name