Ligand: TL7

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 2 100.0% 6W7OA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR BTK BTK_HUMAN 6W7OA Q06187 396 656 659.0 TL7:60701 Type1.5_Back Inactive DFGin 5.9641 13.0637 BLBplus -130.77, 168.26 53.04, 30.28 -64.21, 121.6 37.17, 91.44 71.98, 4.56 out-out out 14.4625 Saltbr-out 15.2427 HRD-in -75.45, -50.93 78.96, -16.73 out-out-out SNCooo out-out ActLoopNT-out 8.1876 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaao APE10-dihe-out -125.26, 14.94 APE9-dihe-in -73.36, 139.85 APE8-dihe-in -76.55, 60.58 APE8-rot-na 30.86 APE67-dihe-in -64.34, -12.26 -50.1, -48.74 APE12-dist-na 17.1583 APE11-dist-na 18.3158 APE10-dist-na 13.6743 APE9-dist-out 8.8077 None None None XRAY 2.17 0.198 0.24 A 277.0 261.0 0 29 29 0 [[402, 653]] 1.0 6w7o TYR_BTK_HUMAN TYR 6.6e-93 316.7 1.0 258.0 258.0 538 539 540 542 544 430 445 449 518 520 519 521.0 579 567 562 561 560 559 558 557 556 475 Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 6W7OB Q06187 396 658 659.0 TL7:60701 Type1.5_Back Inactive DFGin 5.6958 13.0469 BLBplus -127.43, 170.84 53.49, 29.22 -63.0, 121.63 37.69, 90.95 76.44, -4.99 out-out out 14.4002 Saltbr-out 16.3289 HRD-in -75.03, -53.49 79.63, -12.46 out-out-out SNCooo out-out ActLoopNT-out 8.3144 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaao APE10-dihe-out -125.25, 8.08 APE9-dihe-in -68.1, 141.15 APE8-dihe-in -74.31, 63.69 APE8-rot-na 30.16 APE67-dihe-in -66.96, -10.21 -55.5, -47.35 APE12-dist-na 17.2797 APE11-dist-na 18.9134 APE10-dist-na 14.0197 APE9-dist-out 8.9144 None None None XRAY 2.17 0.198 0.24 B 277.0 263.0 0 29 29 0 [[402, 653]] 1.0 6w7o TYR_BTK_HUMAN TYR 6.6e-93 316.7 1.0 258.0 258.0 538 539 540 542 544 430 445 449 518 520 519 521.0 579 567 562 561 560 559 558 557 556 475 Tyrosine-protein kinase BTK

Ligand: TL7

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 2 100.0% 6W7OA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR BTK BTK_HUMAN 6W7OA Q06187 396 656 659.0 TL7:60701 Type1.5_Back Inactive DFGin 5.9641 13.0637 BLBplus -130.77, 168.26 53.04, 30.28 -64.21, 121.6 37.17, 91.44 71.98, 4.56 out-out out 14.4625 Saltbr-out 15.2427 HRD-in -75.45, -50.93 78.96, -16.73 out-out-out SNCooo out-out ActLoopNT-out 8.1876 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaao APE10-dihe-out -125.26, 14.94 APE9-dihe-in -73.36, 139.85 APE8-dihe-in -76.55, 60.58 APE8-rot-na 30.86 APE67-dihe-in -64.34, -12.26 -50.1, -48.74 APE12-dist-na 17.1583 APE11-dist-na 18.3158 APE10-dist-na 13.6743 APE9-dist-out 8.8077 None None None XRAY 2.17 0.198 0.24 A 277.0 261.0 0 29 29 0 [[402, 653]] 1.0 6w7o Homo sapiens TYR_BTK_HUMAN TYR 6.6e-93 316.7 1.0 258.0 258.0 538 539 540 542 544 430 445 449 518 520 519 521.0 579 567 562 561 560 559 558 557 556 475 Tyrosine-protein kinase BTK
TYR BTK BTK_HUMAN 6W7OB Q06187 396 658 659.0 TL7:60701 Type1.5_Back Inactive DFGin 5.6958 13.0469 BLBplus -127.43, 170.84 53.49, 29.22 -63.0, 121.63 37.69, 90.95 76.44, -4.99 out-out out 14.4002 Saltbr-out 16.3289 HRD-in -75.03, -53.49 79.63, -12.46 out-out-out SNCooo out-out ActLoopNT-out 8.3144 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaao APE10-dihe-out -125.25, 8.08 APE9-dihe-in -68.1, 141.15 APE8-dihe-in -74.31, 63.69 APE8-rot-na 30.16 APE67-dihe-in -66.96, -10.21 -55.5, -47.35 APE12-dist-na 17.2797 APE11-dist-na 18.9134 APE10-dist-na 14.0197 APE9-dist-out 8.9144 None None None XRAY 2.17 0.198 0.24 B 277.0 263.0 0 29 29 0 [[402, 653]] 1.0 6w7o Homo sapiens TYR_BTK_HUMAN TYR 6.6e-93 316.7 1.0 258.0 258.0 538 539 540 542 544 430 445 449 518 520 519 521.0 579 567 562 561 560 559 558 557 556 475 Tyrosine-protein kinase BTK

Ligand: TL7

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name